18,767 research outputs found
Dots and Acute Accent Shapes in the DobrejŔo Gospel
This paper examines the distribution of three types of sporadic and infrequent diacritics in the DobrejÅ”o Gospel and their functions: a dot or acute-accent shape over a liquid consonant letter in OCS trŃt/trŃt formations, and, more rarely, over other consonant letters in clusters; a single or multiple acute-accent shape over the letter Š» or Š½ in certain words; and a titlo over unabbreviated words containing OCS trŃt/trŃt formations
Forest Stand Structure and Primary Production in relation to Ecosystem Development, Disturbance, and Canopy Composition
Temperate forests are complex ecosystems that sequester carbon (C) in biomass. C storage is related to ecosystem-scale forest structure, changing over succession, disturbance, and with community composition. We quantified ecosystem biological and physical structure in two forest chronosequences varying in disturbance intensity, and three late successional functional types to examine how multiple structural expressions relate to ecosystem C cycling. We quantified C cycling as wood net primary production (NPP), ecosystem structure as Simpsonās Index, and physical structure as leaf quantity (LAI) and arrangement (rugosity), examining how wood NPP-structure relates to light distribution and use-efficiency. Relationships between structural attributes of biodiversity, LAI, and rugosity differed. Development of rugosity was conserved regardless of disturbance and composition, suggesting optimization of vegetation arrangement over succession. LAI and rugosity showed significant positive productivity trends over succession, particularly within deciduous broadleaf forests, suggesting these measures of structure contain complementary, not redundant, information related to C cycling
Citizens at the Center: A New Approach to Civic Engagement
Offers specific recommendations for giving citizens the tools they need to identify problems and develop solutions in their communities -- and warns against top-down solutions that require people to "plug into" existing programs or campaigns
Little Things That Count: A Call for Organizational Research on Microbusinesses
The purpose of this Incubator is to encourage organizational researchers to attend to the most common type of business in the United Statesāthe microbusiness. After defining and describing these businesses, we propose research questions on defining and managing performance, organizational citizenship, and workāfamily conflict in this novel business setting
Optimization of electron microscopy for human brains with long-term fixation and fixed-frozen sections.
BackgroundAbnormal connectivity across brain regions underlies many neurological disorders including multiple sclerosis, schizophrenia and autism, possibly due to atypical axonal organization within white matter. Attempts at investigating axonal organization on post-mortem human brains have been hindered by the availability of high-quality, morphologically preserved tissue, particularly for neurodevelopmental disorders such as autism. Brains are generally stored in a fixative for long periods of time (often greater than 10 years) and in many cases, already frozen and sectioned on a microtome for histology and immunohistochemistry. Here we present a method to assess the quality and quantity of axons from long-term fixed and frozen-sectioned human brain samples to demonstrate their use for electron microscopy (EM) measures of axonal ultrastructure.ResultsSix samples were collected from white matter below the superior temporal cortex of three typically developing human brains and prepared for EM analyses. Five samples were stored in fixative for over 10 years, two of which were also flash frozen and sectioned on a freezing microtome, and one additional case was fixed for 3 years and sectioned on a freezing microtome. In all six samples, ultrastructural qualitative and quantitative analyses demonstrate that myelinated axons can be identified and counted on the EM images. Although axon density differed between brains, axonal ultrastructure and density was well preserved and did not differ within cases for fixed and frozen tissue. There was no significant difference between cases in axon myelin sheath thickness (g-ratio) or axon diameter; approximately 70% of axons were in the small (0.25 Ī¼m) to medium (0.75 Ī¼m) range. Axon diameter and g-ratio were positively correlated, indicating that larger axons may have thinner myelin sheaths.ConclusionThe current study demonstrates that long term formalin fixed and frozen-sectioned human brain tissue can be used for ultrastructural analyses. Axon integrity is well preserved and can be quantified using the methods presented here. The ability to carry out EM on frozen sections allows for investigation of axonal organization in conjunction with other cellular and histological methods, such as immunohistochemistry and stereology, within the same brain and even within the same frozen cut section
Trends in the Social [Ir]responsibility of American Multinational Corporations: Increased Power, Diminished Accountability
The purpose of this invited essay is to assess the future of the CSR performance of American multinationals in light of several ongoing trends. These trends include companiesā voluntary CSR programs and the global self-regulatory standards for responsible company activities that are developing in almost every industry. Moreover, the decade-long project at the United Nations to identify multinational companiesā responsibilities with respect to international human rights, ultimately spearheaded by Special Representative John Ruggie, has for the first time established global expectations of responsible corporate activity. At the same time, however, legal developments in the United States may be trending in the opposite direction, toward increased power and diminished accountability for corporations. Two legal developments that highlight this counter-trend will frame this discussion. The first, the Supreme Courtās decision in Citizens United v. Federal Election Commission, 558 U.S. 310 (2010) recognizes a constitutional right for corporations to give financial support to a wide range of electioneering activities, including by using corporate funds to pay for and broadcast advertisements for specific candidates for office. The effect is to allow American companies to further consolidate their already substantial political power. The second, the opinion by the U.S. Court of Appeals for the Second Circuit in Kiobel v. Royal Dutch Petroleum, 621 F.3d 111 (2d Cir. 2010), rehāg en banc denied, 642 F.3d 379 (2011), affād, 569 U.S. __ , 133 S. Ct.1659(Apr. 17, 2013), denied the possibility of corporate liability under the Alien Tort Statute for Royal Dutch Shellās employeesā alleged violations of Nigerian community membersā international human rights. A 2-1 majority held instead that violations of international law could only be asserted against natural persons or nations. The Supreme Court granted certiorari and in a decision handed down on April 17, 2013, the Court unanimously affirmed the judgment of the Second Circuit. The five-Justice opinion of the Court held that the ATS cannot be used to redress violations of the law of nations that occur outside the territory of the United States, except in exceptional circumstances not found in Kiobel. Neither the majority opinion nor the concurrence addressed the corporate liability issue, which means that the Second Circuitās ruling on that issue remains the law of the Second Circuit ā an important outcome, given the significance of the Second Circuit as a venue for ATS cases. Taken together, the overall effect of the Second Circuitās rejection of corporate liability for human rights violations and the Supreme Courtās rejection of exterritorial application of the ATS to any defendant, corporate or otherwise, is the substantial evisceration of companiesā legal accountability for international human rights violations under the ATS. On a theoretical level, these decisions send mixed messages about corporate personhood and identity. But on a practical level, the two decisions work in unfortunate concert to increase the already considerable political power of U.S. corporations at home, even as they reduce the risk of legal accountability for their actions abroad. By doing so, they shrink the shadow of the law ā the threat of hard legal regulation ā that has been an important incentive to the adoption of voluntary, soft-law CSR standards. Thus, these legal developments, though ostensibly unrelated to the voluntary pursuit of CSR activity, may in fact act as a disincentive to that activity
Bayesian Inference of Arrival Rate and Substitution Behavior from Sales Transaction Data with Stockouts
When an item goes out of stock, sales transaction data no longer reflect the
original customer demand, since some customers leave with no purchase while
others substitute alternative products for the one that was out of stock. Here
we develop a Bayesian hierarchical model for inferring the underlying customer
arrival rate and choice model from sales transaction data and the corresponding
stock levels. The model uses a nonhomogeneous Poisson process to allow the
arrival rate to vary throughout the day, and allows for a variety of choice
models. Model parameters are inferred using a stochastic gradient MCMC
algorithm that can scale to large transaction databases. We fit the model to
data from a local bakery and show that it is able to make accurate
out-of-sample predictions, and to provide actionable insight into lost cookie
sales
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