A calculus for distrust and mistrust

Properties of trust are becoming widely studied in several applications within the computational domain. On the contrary, negative trust attribution is less well-defined and related issues are yet to be approached and resolved. We present a natural deduction calculus for trust protocols and its negative forms, distrust and mistrust. The calculus deals efficiently with forms of trust transitivity and negative trust multiplication and we briefly illustrate some possible applications

Successful Xenografts of Second Trimester Human Fetal Brain and Retinal Tissue in the Anterior Chamber of the Eye of Adult Immunosuppressed Rats

Successful xenografting of first trimester human fetal CNS tissue and retina has been reported in the literature. We wished to test the feasibility ofusing the anterior chamber ofthe rat eye to support the development of more mature human fetal xenografts. Here we report on the successful outcome of human brain and retinal transplants. Adult host rats immunosuppressed with cyclosporin A accepted these xenografts and supported their further development. Periodic examination of the host eyes using a direct ophthalmoscope or an ophthalmic slit lamp permitted direct visual monitoring of the health and growth of the transplants. Histologically it was possible to identify neuronal, macroglial, and microglial (macrophage) cell types within the grafts. Mitotic activity and histogenetic differentiation took place. Blood vessels filled with hematic cells were commonly present within the grafts. The walls of these vessels prevented the leakageofhorseradish peroxidase, suggesting the presence of a functional brain-blood barrier in the graft. These results indicate that it is possible to use a small animal model to study normal and pathological phenomena oniate fetal human neural tissues. Our group has already taken advantage of the model to achieve HIV infectivity offetal human brain outside the human body

Profile of Alumni from the Class of 1992, part two: Reflections on the Western Experience

Results of the survey of 1992 Western graduates conducted in 1996

Sensationalism made real : the role of realism in the production of sensational affect

Like all complicated relationships, that between realism and sensationalism has been subject to a good deal of rumour and speculation. In what might be described as the pair's first critical encounter – in an 1852 joint review of W. M. Thackeray's The History of Henry Esmond and Wilkie Collins's proto-sensation novel Basil – a critic for Bentley's Miscellany intimates that a partnership between two such different forms is anything but likely. “We have,” he explains, “put these two books ‘over against’ each other, to use one of Mr. Thackeray's favourite Queen-Anne-isms, because they have no kind of family resemblance. They are, indeed, as unlike each other as any two books can be. They constitute a kind of literary antithesis” (“Esmond” 576). The inherently contradictory nature of this originary “over against” gesture – conflating proximity and distance, contiguity and difference – sets the keynote for subsequent discussions, contemporaneous and current, of a generic relationship that continues to attract and elude definition