14 research outputs found

    SEOM Clinical Guideline for the diagnosis and treatment of esophageal cancer (2016)

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    Esophageal cancer (EC) is an aggressive tumor that represents the 6th most common cause of cancer death worldwide. The estimated incidence in Spain is 2090 cases/year. Two main pathological subtypes exist, squamous cell carcinoma and adenocarcinoma. The main differences between them are localization and underlying factors which are the principal cause of the recent incidence changes observed in west countries. Staging techniques and treatment options which combine surgery, chemotherapy and radiotherapy, reflected the high complexity of the EC management. An undeniably multidisciplinary approach is, therefore, required. In this guide, we review the status of current diagnosis and treatment, define evidence and propose recommendations

    SEOM clinical guideline for the diagnosis and treatment of gastric cancer (GC) and gastroesophageal junction adenocarcinoma (GEJA) (2019)

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    Gastric cancer (GC) is the fifth most common cancer worldwide with a varied geographic distribution and an aggressive behavior. In Spain, it represents the sixth cause of cancer death. In Western countries, the incidence is decreasing slightly, with an increase in gastroesophageal junction adenocarcinoma (GEJA), a different entity that we separate specifically in the guideline. Molecular biology advances have been done recently, but do not yet lead to the choice in treatment approach except in advanced disease with overexpression of HER2. Endoscopic resection in very early stage, perioperative chemotherapy in locally advanced tumors and preliminary immune therapy resulting in advanced disease are the main treatment innovations in the GC/GEJA treatment. We describe the different evidences and recommendations following the statements of the American College of Physicians

    Bio-analytical Assay Methods used in Therapeutic Drug Monitoring of Antiretroviral Drugs-A Review

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    Search for excited quarks in the y+jet final state in proton-proton collisions at s=8 TeV

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    A search for excited quarks decaying into the γ+jet final state is presented. The analysis is based on data corresponding to an integrated luminosity of 19.7 fb −1 collected by the CMS experiment in proton–proton collisions at s=8 TeV at the LHC. Events with photons and jets with high transverse momenta are selected and the γ+jet invariant mass distribution is studied to search for a resonance peak. The 95% confidence level upper limits on the product of cross section and branching fraction are evaluated as a function of the excited quark mass. Limits on excited quarks are presented as a function of their mass and coupling strength; masses below 3.5 TeV are excluded at 95% confidence level for unit couplings to their standard model partners

    Search for new physics in events with same-sign dileptons and jets in pp collisions at root s = 8 TeV (vol 01, pg 163, 2014)

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    Made available in DSpace on 2015-06-25T12:55:21Z (GMT). No. of bitstreams: 0 Previous issue date: 2015Made available in DSpace on 2015-11-26T15:18:27Z (GMT). No. of bitstreams: 2 2-s2.0-84921407514.pdf: 236271 bytes, checksum: e9b67a8637560201105108af720ed1ff (MD5) 2-s2.0-84921407514.pdf.txt: 43801 bytes, checksum: a87aa49408e3fa7bb288c13764b65c79 (MD5) Previous issue date: 20152015111

    Search for the associated production of the Higgs boson with a top-quark pair

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    2014
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