19 research outputs found
Vitamin B6 and riboflavin, their metabolic interaction and relationship with MTHFR genotype, in adults aged 18-102 years
Public involvement in the governance of population-level biomedical research: unresolved questions and future directions.
Population-level biomedical research offers new opportunities to improve population health, but also raises new challenges to traditional systems of research governance and ethical oversight. Partly in response to these challenges, various models of public involvement in research are being introduced. Yet, the ways in which public involvement should meet governance challenges are not well understood. We conducted a qualitative study with 36 experts and stakeholders using the World Café method to identify key governance challenges and explore how public involvement can meet these challenges. This brief report discusses four cross-cutting themes from the study: the need to move beyond individual consent; issues in benefit and data sharing; the challenge of delineating and understanding publics; and the goal of clarifying justifications for public involvement. The report aims to provide a starting point for making sense of the relationship between public involvement and the governance of population-level biomedical research, showing connections, potential solutions and issues arising at their intersection. We suggest that, in population-level biomedical research, there is a pressing need for a shift away from conventional governance frameworks focused on the individual and towards a focus on collectives, as well as to foreground ethical issues around social justice and develop ways to address cultural diversity, value pluralism and competing stakeholder interests. There are many unresolved questions around how this shift could be realised, but these unresolved questions should form the basis for developing justificatory accounts and frameworks for suitable collective models of public involvement in population-level biomedical research governance
Inside the university technology transfer office: mission statement analysis
The focus of our paper is to qualitatively explore the mission statements components of university TTOs using Pearce and Davidâs (Acad Manag Exec 1(2):109â115, 1987) eight components. Mission statements are the organizationâs central defining purpose and focus. In essence an organizationsâ raison dâetre. Given the growing importance of the role TTOs now play, understanding components of mission statements is timely, particularly during the first phase of TTO developments. To provide insights concerning these issues our study is set in the Republic of Ireland, which has one of the top performing university and public research organization technology transfer system within the European Union. Using Pearce and David (1987) well established eight mission statement components we analyzed seven Irish university TTO mission statements. We also conducted quantitative analysis on the number of mission statement components and selected variables. We found that university TTO mission statements focused primarily on two mission componentsâtarget customers and markets and principal services. From our quantitative analysis we found moderate positive correlations between patents granted and number of mission statement components. Furthermore we found there was a positive correlation between grants granted outside of Ireland and the number of mission components. Our results, albeit they are tempered by a small sample of data, have pertinent implications for TTOs
Case-based User Profiling in a Personal Travel Assistant
this paper we present an architecture for a Personal Travel Assistant (PTA). We focus on the ability of this PTA to elaborate a user's travel requirements and evaluate offers. These decisions are based on a User Profile that has the interesting characteristic that it adopts a lazy policy on learning from a user's past behavior