Safe and private pedestrian detection by a low-cost fiber-optic specklegram

Surveillance is becoming more and more important in the recent years. In many cities, cameras have been set to look after parks, streets, roads, facilities and so on, however this fact is rising concerns about privacy. In this work, an alternative surveillance method which gather at once security and privacy has been propose and tested. Based on fiber optic specklegram technology; a system consisting of a fiber optic, a coherent light source and a photodetector has been placed under a carpet for detecting people walking over it and its accuracy, regarding measuring the steps, have been measured. Results suggest that using low exposed geometries along the carpet and basic processing methods, it is possible to detect with more than 95% of accuracy the number of steps done by the person walking over the carpet.This work has been supported by the projects TEC2013-47264-C2-1-R and TEC2016-76021-C2-2-R of the Spanish government and by a Parliament of Cantabria postdoc grant

Machine learning for turning optical Fiber Specklegram Sensor into a spatially-resolved sensing system. Proof of concept

Fiber Specklegram Sensors (FSSs) are highly sensitive to external perturbations, however, trying to locate perturbation's position remains as a barely addressed study. In this work, a system able to classify perturbations according to the place they have been caused along a multimode optical fiber has been designed. As proof of concept, a multimode optical fiber has been perturbated in different points, recording the videos of the perturbations in the speckle pattern, processing these videos, training with them a machine learning algorithm, and classifying further perturbations based on the spatial locations they were generated. The results show classifications up to 99% when the system has to categorize among three different locations lowering to 71% when the locations rise to ten.This work was supported by the Spanish Government through the Ministry of Economy and Competitiveness project TEC2016-76021-C2-2-R (AEI/FEDER, UE)

Low-cost fiber specklegram sensor for noncontact continuous patient monitoring

Different low-cost approaches based on fiber specklegram sensors are employed to measure the physiological activity of patients lying in bed. This study is conducted over 20 volunteers to measure the movement and heart rate (HR) using two different sensor designs placed at two different bed locations. Three different processing methods are developed and tested in order to extract useful information from the measured data. The results suggest that a stretched fiber optic configuration under the head of the person lying in bed is the optimal configuration to detect HR and motion, nonetheless the other tested possibilities also exhibit remarkably good performances. On the other hand, the three proposed processing methods also achieve a good precision in the HR detection. The sensor implementation is simple, not requiring any special conditions, and it provides robust performance. This leads to the conclusion that fiber specklegram technology is a feasible method to be used in real situations for heartbeat and movement monitoring.This work has been supported by the Spanish Government through the Ministry of Economy and Competitiveness projects TEC2013-47264-C2-1-R and TEC2016-76021-C2-2-R

Sleep monitoring by a specklegram fiber optic sensor

Sleep monitoring is becoming more and more popular. This is due to the considerably large number of pathologies and illness related to sleep disorders.In this work a long-termmonitoring system based on a fiber-optic specklegram sensor is presented. The system has been tested under real scenarios and compared with a commercial wrist-based actigrapher. The results suggest that our sensor is highly accurate on detecting movements and can be far more precise than traditional wrist-based actigraphers.This work has beensupported by the Spanish Government through the Ministry of Economy and Competitiveness projects TEC2013-47264-C2-1-R and TEC2016-76021-C2-2-R (AEI/FEDER, UE)

Dispositivo de detección de actividad/inactividad fisiológica basado en fibra óptica

Dispositivo de detección de actividad/inactividad fisiológica configurado para permitir la detección de los estados de actividad o inactividad fisiológica de personas, de forma no intrusiva y sin contacto directo, basado en la detección de movimientos y vibraciones utilizando la medida de los cambios en el patrón Speckle producido en una fibra óptica multi-modo cuando se conduce por su interior luz coherente, que comprende: al menos una fibra óptica multi-modo como elemento de transducción, unida a una fuente de luz coherente y a un detector óptico; un bloque de procesado conectado al detector óptico, configurado para implementar el método de procesado necesario para emitir una decisión; elementos de conexionado configurados para conectar/desconectar la fibra óptica multi-modo a/del detector óptico y a/de la fuente de luz coherente. Un método de procesado configurado para detectar los estados de actividad o inactividad fisiológica de personas, utilizando el dispositivo definido.Solicitud: 201600626 (22.07.2016)Nº Pub. de Solicitud: ES2610181A1 (26.04.2017)Nº de Patente: ES2610181B2 (27.03.2018

Immunohistochemical detection of p53 and pp53 Ser392 in canine hemangiomas and hemangiosarcomas located in the skin

[EN] Background: p53 protein is essential for the regulation of cell proliferation. Aberrant accumulation of it usually occurs in cutaneous malignancies. Mutant p53 is detected by immunohistochemistry because it is more stable than the wild-type p53. However, post-translational modifications of p53 in response to ultraviolet radiation are important mechanisms of wild-type p53 stabilization, leading to positive staining in the absence of mutation. The aims were: 1) to analyze the immunohistochemical expression of p53 and phospho-p53 Serine392 in canine skin endothelial tumours; and 2) to determine if any relationship exists between p53 and phospho-p53 Serine392 overexpression and cell proliferation. Results: p53 and phospho-p53 Serine392 immunolabeling was examined in 40 canine cutaneous endothelial tumours (13 hemangiomas and 27 hemangiosarcomas). Their expression was associated with tumour size, hemangiosarcoma stage (dermal versus hypodermal), histological diagnosis and proliferative activity (mitotic count and Ki-67 index). Statistical analysis revealed a significant increase of p53 immunoreactivity in hemangiosarcomas (median, 74.61%; interquartile range [IQR], 66.97-82.98%) versus hemangiomas (median, 0%; IQR, 0-20.91%) (p <.001) and in well-differentiated hemangiosarcomas (median, 82.40%; IQR, 66.49-83.17%) versus hemangiomas (p =.002). Phospho-p53 Serine392 immunoreactivity was significantly higher in hemangiosarcomas (median, 53.80%; IQR, 0-69.50%) than in hemangiomas (median, 0%; IQR, 0.0%) (p <.001). Positive correlation of the overexpression of p53 and phospho-p53 Serine392 with mitotic count and Ki-67 index was found in the cutaneous vascular tumours (p <.001). The Ki-67 index of the hemangiomas (median, 0.50%; IQR, 0-2.80%) was significantly lower than that of the hemangiosarcomas (median, 34.85%; IQR, 23.88-42.33%) (p <.001), and that specifically of well-differentiated hemangiosarcomas (median, 24.60%; IQR, 15.45-39.35%) (p =.001). Immunolabeling of 18 visceral hemangiosarcomas showed that the p53 (median, 41.59%; IQR, 26.89-64.87%) and phospho-p53 Serine392 (median, 0%; IQR, 0-22.53%) indexes were significantly lower than those of skin (p =.001; p =.006, respectively). Conclusions: The p53 and phospho-p53 Serine392overexpression together with high proliferative activity in hemangiosarcomas versus hemangiomas indicated that p53 might play a role in the acquisition of malignant phenotypes in cutaneous endothelial neoplasms in dogs. The Ki-67 index may be useful in distinguishing canine well-differentiated hemangiosarcomas from hemangiomasS

Desafíos actuales de la educación superior

El presente libro corresponde al trabajo investigativo realizado por sus autores frente a los desafíos que enfrenta y enfrentará la educación en tiempos actuales (provisional)

POF-based specklegram sensor for continuous patient monitoring

In this work, different schemes to detect vital signs of bedding patients are proposed and experimentally verified. Employing speckle in multimode polymer optical fibers as sensing element, the fiber is placed under the bed linen to collect the small movements provoked by the patient. This kind of sensor takes advantage of the remarkably high sensitivity exhibited by fiber specklegram sensors. Based on a proper sizing of the employed multimode fiber, it can be placed in different locations trying to favour the detection of heart beating or movement. When the patient does not exhibit any conscious movement (e.g. while he is sleeping) its heart rate can be measured.This work has been supported by the project TEC2013-47264-C2-1-R of the Spanish Government and by a Parliament of Cantabria postdoc grant

Deep Underground Neutrino Experiment (DUNE) Near Detector Conceptual Design Report

International audienceThe Deep Underground Neutrino Experiment (DUNE) is an international, world-class experiment aimed at exploring fundamental questions about the universe that are at the forefront of astrophysics and particle physics research. DUNE will study questions pertaining to the preponderance of matter over antimatter in the early universe, the dynamics of supernovae, the subtleties of neutrino interaction physics, and a number of beyond the Standard Model topics accessible in a powerful neutrino beam. A critical component of the DUNE physics program involves the study of changes in a powerful beam of neutrinos, i.e., neutrino oscillations, as the neutrinos propagate a long distance. The experiment consists of a near detector, sited close to the source of the beam, and a far detector, sited along the beam at a large distance. This document, the DUNE Near Detector Conceptual Design Report (CDR), describes the design of the DUNE near detector and the science program that drives the design and technology choices. The goals and requirements underlying the design, along with projected performance are given. It serves as a starting point for a more detailed design that will be described in future documents

Deep Underground Neutrino Experiment (DUNE), Far Detector Technical Design Report, Volume I Introduction to DUNE

International audienceThe preponderance of matter over antimatter in the early universe, the dynamics of the supernovae that produced the heavy elements necessary for life, and whether protons eventually decay—these mysteries at the forefront of particle physics and astrophysics are key to understanding the early evolution of our universe, its current state, and its eventual fate. The Deep Underground Neutrino Experiment (DUNE) is an international world-class experiment dedicated to addressing these questions as it searches for leptonic charge-parity symmetry violation, stands ready to capture supernova neutrino bursts, and seeks to observe nucleon decay as a signature of a grand unified theory underlying the standard model. The DUNE far detector technical design report (TDR) describes the DUNE physics program and the technical designs of the single- and dual-phase DUNE liquid argon TPC far detector modules. This TDR is intended to justify the technical choices for the far detector that flow down from the high-level physics goals through requirements at all levels of the Project. Volume I contains an executive summary that introduces the DUNE science program, the far detector and the strategy for its modular designs, and the organization and management of the Project. The remainder of Volume I provides more detail on the science program that drives the choice of detector technologies and on the technologies themselves. It also introduces the designs for the DUNE near detector and the DUNE computing model, for which DUNE is planning design reports. Volume II of this TDR describes DUNE's physics program in detail. Volume III describes the technical coordination required for the far detector design, construction, installation, and integration, and its organizational structure. Volume IV describes the single-phase far detector technology. A planned Volume V will describe the dual-phase technology