Breakdown of anomalous channeling with ion energy for accurate strain determination in gan-based heterostructures

The influence of the beam energy on the determination of strain state with ion channeling in GaN-based heterostructures (HSs) is addressed. Experimental results show that anomalous channeling may hinder an accurate analysis due to the steering effects at the HS interface, which are more intense at lower ion energies. The experimental angular scans have been well reproduced by Monte Carlo simulations, correlating the steering effects with the close encounter probability at the interface. Consequently, limitations in the determination of the strain state by ion channeling can be overcome by selecting the adequate beam energy

Results of sardine daily egg production off the northern coast of Spain for April 2008.

This document presents the results of the SAREVA0408 ichthyoplankton survey conducted by IEO (Instituto Español de Oceanografía). This survey was carried out on board R/V Cornide de Saavedra during April 2008. The covered area was the North and North-western Iberian Peninsula waters and the inner part of the Bay of Biscay (from 42°N to 45°N).The present paper includes data on sardine (Sardina pilchardus) egg distribution and abundance from the SAREVA0408 survey, as well as the estimation of daily egg production (DEPM) for sardine in the North Spanish Atlantic, Cantabrian waters and south of the Bay of Biscay

Preliminary results of sardine daily egg production off the northern coast of Spain in April 2008.

This document presents the results of the SAREVA0408 ichthyoplankton survey conducted by IEO (Instituto Español de Oceanografía). This survey was carried out on board R/V Cornide de Saavedra for April 2008. The covered area was the North and North-western Iberian Peninsula waters and the inner part of the Bay of Biscay (from 42°N to 45°N).The present paper includes data on sardine (Sardina pilchardus) egg distribution and abundance from the SAREVA0408 survey, as well as the estimation of daily egg production (DEPM) for sardine in the north Spanish Atlantic, Cantabrian waters and south of the Bay of Biscay

SysGpr: System of Generation of Pseudo-realistic Synthetic Signals

[EN] Signals obtained from sensors are widely used in different scientific fields. However, the resources to obtain the data are not always available due to structural constraints, physical, economic, environmental, and data collection failures, etc. It is in this scenario that the generation of synthetic data is established. The generation of synthetic data has several benefits, such as, reducing waiting times compared to the long periods required by some sensors to obtain large volumes of samples. In addition, the generated data can be as robust as users need it to be. For this reason, this paper presents a pseudo-realistic synthetic signal generation system for use in the validation of methods and design of experiments. The proposed signal generation method makes use of statistical models and the gradient of the signal to generate new data. The developed system is open for the public, available as a web tool.[ES] Las señales obtenidas desde sensores son ampliamente utilizadas en diferentes campos científicos. Sin embargo, no siempre se dispone de los recursos necesarios para obtener dichos datos, debido a limitaciones estructurales, físicas, económicas, ambientales, fallos en la recolección de los datos, etc. Es en este escenario limitante, donde se erige la generación de datos sintéticos. La generación de datos sintéticos tiene la característica de reducir tiempos de espera frente a los largos periodos temporales que necesitan algunos sensores para obtener grandes volúmenes de muestras. Además, los datos generados pueden llegar a ser todo lo robustos que los usuarios necesiten. Por ello este trabajo presenta un sistema de generación de señales sintéticas con carácter pseudo-realista para su uso aplicado a la validación de métodos y diseño de experimentos. El método de la generación de señales propuesto, hace uso de modelos estadísticos y el comportamiento del gradiente de la señal para ir generando nuevos datos. El sistema desarrollado se encuentra disponible públicamente como herramienta web.Este trabajo ha sido parcialmente financiado mediante el proyecto DPI2013-47347-C2-2-R.León, F.; Rodríguez-Lozano, FJ.; Cubero-Fernández, A.; Palomares, JM.; Olivares., J. (2019). SysGpr: Sistema de generación de señales sintéticas pseudo-realistas. Revista Iberoamericana de Automática e Informática. 16(3):369-379. https://doi.org/10.4995/riai.2019.10025SWORD36937916

Genetic inactivation and pharmacological blockade of sigma-1 receptors prevent paclitaxel-induced sensory-nerve mitochondrial abnormalities and neuropathic pain in mice

Background Paclitaxel, a widely-used antineoplastic drug, produces a painful peripheral neuropathy that in rodents is associated with peripheral-nerve mitochondrial alterations. The sigma-1 receptor (σ1R) is a ligand-regulated molecular chaperone involved in mitochondrial calcium homeostasis and pain hypersensitivity. This receptor plays a key role in paclitaxel-induced neuropathic pain, but it is not known whether it also modulates mitochondrial abnormalities. In this study, we used a mouse model of paclitaxel-induced neuropathic pain to test the involvement of the σ1R in the mitochondrial abnormalities associated with paclitaxel, by using genetic (σ1R knockout mice) and pharmacological (σ1R antagonist) approaches.Results Paclitaxel administration to wild-type (WT) mice produced cold- and mechanical-allodynia, and an increase in the frequency of swollen and vacuolated mitochondria in myelinated A-fibers, but not in C-fibers, of the saphenous nerve. Behavioral and mitochondrial alterations were marked at 10 days after paclitaxel-administration and had resolved at day 28. In contrast, paclitaxel treatment did not induce allodynia or mitochondrial abnormalities in σ1R knockout mice. Moreover, the prophylactic treatment of WT mice with BD-1063 also prevented the neuropathic pain and mitochondrial abnormalities induced by paclitaxel.Conclusions These results suggest that activation of the σ1R is necessary for development of the sensory nerve mitochondrial damage and neuropathic pain produced by paclitaxel. Therefore, σ1R antagonists might have therapeutic value for the prevention of paclitaxel-induced neuropathy.This study was partially supported by grant P11-CTS-7649 and grant CTS-109 from Junta de Andalucía, FEDER funds, a grant from Esteve, and a grant from the Centro para el Desarrollo Tecnológico Industrial (NeoGenius Pharma project). F. R. Nieto was supported by a FPU grant from the Spanish Ministerio de Educación y Ciencia (MEC) and C. M. Cendán by the Research Program of the University of Granada

Anti-inflammatory and regenerative effects of MKARE® Eggshell Membrane: An in vitro osteoarthritis model and placebo-controlled clinical study

[EN]MKARE®, a 100% natural ingredient derived from fresh eggshell membrane (ESM), has a rich composition in bioactive compounds like collagen, hyaluronic acid, and elastin. These components are beneficial for managing osteoarthritis (OA) due to their anti-inflammatory and regenerative properties. Highlighting the significance of freshness, our research has shown that the effectiveness of MKARE® is higher than that of other commercial products based on ESM that have been stored for several days at room temperature, losing their bioactive compounds. This study explores the MKARE® anti-inflammatory capacity through an in vitro and clinical analyses, demonstrating its ability to alleviate OA symptoms and improve joint health. This underscores the crucial role of freshness in optimizing the therapeutic benefits.S

Characterising the spawning habitats of sardine from the northern coast of Spain in april 2008

This document presents the results of the analysis from sardine (Sardina pilchardus) egg densities in relation to environmental (temperature, salinity) and geographic (longitude, depth) variables. Data were obtained from the SAREVA0408 ichthyoplankton survey conducted by IEO (Instituto Español de Oceanografía) in April 2008. Quotient analysis, temperature-salinity plots and time distribution for eggs per stage of development, were employed to study spawning habitat of the sardine off north Spanish Atlantic, Cantabrian waters and south of the Bay of Biscay

Precise measurement of near-barrier He 8 + Pb 208 elastic scattering: Comparison with He 6

et al.Dramatic differences in the elastic scattering of the neutron rich nuclei He6 and He8 are found when new high quality data for the He8+Pb208 system are compared with previously published He6+Pb208 data at the same laboratory frame incident energy. The new He8 data are of the same level of detail as for stable beams. When comparing them with those previously obtained for He6+Pb208 at the same energy, it is possible to determine from the data alone that He6 has a much longer range absorption than He8. However, both nuclei show significant absorption beyond their strong absorption radii. While it has been known for a long time that elastic scattering at energies around the barrier only determines the optical potential over a small distance in radial space, typically ±0.5 fm or so, both the He6 and the He8 imaginary potentials obtained from various optical model fits to these data are the same over a much wider range of ±1.5 fm. ©2016 American Physical SocietyThis work was supported in part by Grant No. FPA2010-22131- C02-01 (FINURA) and Grant No. FPA2013-47327-C2-1-R from the Spanish Ministry of Economy and Competitiveness, UNAM-PAPIIT IA101616 (Mexico), Grant No. N202 033637 from the Ministry of Science and Higher Education of Poland, and Contract No. EUI2009-04163 (EUROGENESIS) from the European Science Foundation.Peer Reviewe

Scattering of the halo nucleus 11Li and its core 9Li on 208Pb at energies around the Coulomb barrier

The first measurement of the elastic scattering of the halo nucleus 11Li and its core 9Li on 208Pb at energies around the Coulomb barrier is presented. The 11Li reaction showed a large cross section for the breakup channel, even at energies well below the barrier. The analysis of the 11Li + 208Pb scattering data in terms of the continuum-discretized coupled-channel calculations indicates that the effect of the coupling to the breakup channels produces a strong suppression of the elastic cross section at energies above and below the barrier. This effect is mainly due to the strong Coulomb coupling to the dipole states in the low-lying continuum of 11Li

Reaction of the halo nucleus be on heavy targets at energies around the coulomb barrier

Presented at the XXXIII Mazurian Lakes Conference on Physics, Piaski, Poland, September 1–7, 2013.-- et al.New data for the reaction 11Be on 197Au at E lab = 31:9 MeV are presented. The angular distributions of the inelastically scattered 11Be and the 10Be fragments coming from the 11Be dissociation have been extracted and compared with semiclassical and coupled-channels calculations in an angular range θlab = 13deg;-46deg; for the detected Be fragment.This work was supported by the Spanish Government under the projects FPA2009-07387, FPA2009-07653, FPA2009-08848, FPA2012-32443 and Consolider CPAN CSD2007-00042; the Helmholtz Association (HGT) through the Nuclear Astrophysics Virtual Institute (VH-VI-417); ATI Sistemas; a Natural Sciences and Engineering Research Council of Canada grant. TRIUMF receives federal funding via a contribution agreement through the National Research Council of Canada.Peer Reviewe