2,077 research outputs found

    Polarizing Bubble Collisions

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    We predict the polarization of cosmic microwave background (CMB) photons that results from a cosmic bubble collision. The polarization is purely E-mode, symmetric around the axis pointing towards the collision bubble, and has several salient features in its radial dependence that can help distinguish it from a more conventional explanation for unusually cold or hot features in the CMB sky. The anomalous "cold spot" detected by the Wilkinson Microwave Anisotropy Probe (WMAP) satellite is a candidate for a feature produced by such a collision, and the Planck satellite and other proposed surveys will measure the polarization on it in the near future. The detection of such a collision would provide compelling evidence for the string theory landscape.Comment: Published version. 15 pages, 8 figure

    A serum-free media formulation for cultured meat production supports bovine satellite cell differentiation in the absence of serum starvation

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    Cultured meat production requires the robust differentiation of satellite cells into mature muscle fibres without the use of animal-derived components. Current protocols induce myogenic differentiation in vitro through serum starvation, that is, an abrupt reduction in serum concentration. Here we used RNA sequencing to investigate the transcriptomic remodelling of bovine satellite cells during myogenic differentiation induced by serum starvation. We characterized canonical myogenic gene expression, and identified surface receptors upregulated during the early phase of differentiation, including IGF1R, TFRC and LPAR1. Supplementation of ligands to these receptors enabled the formulation of a chemically defined media that induced differentiation in the absence of serum starvation and/or transgene expression. Serum-free myogenic differentiation was of similar extent to that induced by serum starvation, as evaluated by transcriptome analysis, protein expression and the presence of a functional contractile apparatus. Moreover, the serum-free differentiation media supported the fabrication of three-dimensional bioartificial muscle constructs, demonstrating its suitability for cultured beef production.Bovine satellite cells undergoing myogenic differentiation in a chemically defined, serum-free medium are comparable to those undergoing serum starvation-demonstrating the suitability of this formulation for cultured meat production

    Path-flow analysis model for anthropometric, hydrodynamic and biomechanical variables in age-group swimmers

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    The goal of competitive swimming is to travel the event distance as fast as possible. The identification of the parameters that predict swimming performances is one of the main aims of the swimming “science” community

    El profesorado universitario ante el aprendizaje-servicio: variables explicativas

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    Introducción: La metodología del aprendizaje-servicio es una de las más adecuadas para adaptarse a los cambios y a los nuevos retos sociales y educativos en el espacio universitario. Se trata de un enfoque que promueve un aprendizaje de tipo experiencial en el que el protagonismo no está en el profesorado sino en quienes ofrecen y en quienes reciben el servicio. Las razones para proponer esta metodología en las aulas universitarias son muy variadas, y tienen que ver con la mejora de los procesos educativos, la formación ética y ciudadana del alumnado, así como con la mejora de los vínculos existentes entre universidad y sociedad. Concretamente, nuestro objetivo en este trabajo es analizar cuáles son las variables que explican que un profesor universitario introduzca la metodología de aprendizaje-servicio en su quehacer docente. Metodología: Con este propósito, hemos llevado a cabo un estudio con 1903 docentes de 6 universidades españolas a los que se les ha aplicado el “Cuestionario sobre Práctica docente y Actitud del profesorado universitario hacia la Innovación” (CUPAIN). Resultados: Con los datos obtenidos realizamos una regresión logística con la finalidad de estimar la probabilidad de que un profesor universitario utilice o no el aprendizaje servicio según variables sociodemográficas (sexo, edad, tipo de materia, alumnos matriculados, situación administrativa, experiencia, ciclo), la práctica docente, el acuerdo con el compromiso social de la universidad y el interés por prácticas docentes innovadoras; y, posteriormente, un análisis de varianza multivariado (MANOVA) 5 X 2, y una prueba chi-cuadrado. Discusión y conclusiones: El análisis de los datos nos permite concluir que de todas las variables analizadas la que mejor predice el empleo del ApS por parte de los docentes es su acuerdo con el compromiso social de la universidad, de tal forma que la probabilidad de utilizar esta metodología es 3.52 veces mayor que no hacerlo.Introduction: The service-learning methodology is one of the most appropriate to adapt to changes, and new social and educational challenges in the Higher Education environment. This is an approach that promotes an experiential type of learning in which the teaching staff does not play a prominent role, but those who offer and receive the service. There are several reasons for proposing this methodology in the university classrooms, and they have to do with the improvement of the educational processes, students’ ethical and civic education, as well as with the improvement of the existing linkages between university and society. Specifically, our objective in this paper is to analyze which are the variables explaining the introduction of the service-learning methodology by a university professor. Methodology: To this end, a study involving 1903 professors from 6 Spanish universities was carried out. They were administered the “Questionnaire on Teaching Practice and Attitude of University Professors towards Innovation” (CUPAIN). Results: With the data obtained, a logistic regression was performed in order to estimate the probability that a university professor uses service learning according to sociodemographic variables (sex, age, type of subject, students enrolled, administrative situation, experience, cycle), teaching practice, agreement with the social commitment of the university and interest in innovative teaching practices; subsequently, a multivariate analysis of variance (MANOVA) 5 X 2, and a Chi-square test were applied. Discussion and Conclusions: The data analysis allowed us to conclude that, of all the analyzed variables, the one that better predicts the use of SL by the professors is their engagement with the university’s social commitment, in such a way that the probability of using this methodology is 3.52 times higher than not doing it

    Path-flow analysis model for anthropometric, hydrodynamic and biomechanical variables in age-group swimmers

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    The aim of this research was to develop a path-flow analysis model for age-group swimmer’s speed based on anthropomeric, hydrodynamic and biomechanical determinants

    Evolution on Swimming Science Research: content analysis of the “Biomechanics and Medicine in Swimming” Proceedings Books from 1971 to 2006

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    Swimming seems to be one of the sports more studied . More than one decade ago, Clarys (1996) made an content analysis of the research about swimming. However, in these last 13 years several developments happened in the aquatic activities

    Unique Continuation for Schr\"odinger Evolutions, with applications to profiles of concentration and traveling waves

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    We prove unique continuation properties for solutions of the evolution Schr\"odinger equation with time dependent potentials. As an application of our method we also obtain results concerning the possible concentration profiles of blow up solutions and the possible profiles of the traveling waves solutions of semi-linear Schr\"odinger equations.Comment: 23 page

    Radiative Mechanism to Light Fermion Masses in the MSSM

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    In a previous work we have showed that the Z2{\cal Z}_{2}^{\prime} Symmetry, imply that the light fermions, the electron and the quarks, u,du,d and ss, get their masses only at one loop level. Here, we considere the more general hypothesis for flavour mixing in the sfermion sector in the MSSM. Then, we present our results to the masses of these light fermions and as a final result we can explain why the ss quark is heavier than the u,du,d quarks. This mechanism is in agrement with the experimental constraint on the sfermion's masses values.Comment: 22 pages, 8 figures, TeX mistakes corrected, accepted for publication in JHE
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