Improving Psychological Trauma Awareness for Culturally Responsive Care: A DNP Project

Racism and racial discrimination occur in a variety of forms (Kendi, 2017). Both can contribute to poor mental health outcomes in the United States (Alvarez, Liang, & Neville, 2016; Comas-Diaz, Hall, & Neville, 2019; Levy, 2019; Malott & Schaefle, 2015; Williams, Lawrence, Davis, & Vu, 2019). These social conditions have been identified as chronic stressors that can illicit trauma symptoms, result in post-traumatic stress disorder (PTSD), and contribute to increased suicidality (French et al., 2020). Providers should understand the ramifications of the psychological trauma that can occur and endeavor to deliver evidence-based solutions. This doctoral project was designed to develop, implement, and evaluate a Trauma-Informed Care Program to improve provider awareness, knowledge, and confidence. Using the modified Trauma Informed System Change Instrument (TISCI), a significant improvement was seen in these areas, even among providers who had some previous understanding of trauma-informed care. Utilization of a trauma-informed care model allows for successful provision of culturally responsive, trauma-informed health care for patients who have experienced racism and racial discrimination

A Study on the Impact of Climate Variability/Change on Water Resources in the Philippines

This paper presents an effort toward a better understanding of the potential impact of climate variability and change on the hydrology and water resources in the Philippines. Impacts of extreme events such as droughts are discussed. A preliminary study on the variability of inflow in relation to rainfall at the major dams in Luzon and the natural water reservoir of Lake Lanao is presented. Areas for future study are also mentioned.watershed

A Study on the Impact of Climate Variability/Change on Water Resources in the Philippines

This paper presents an effort toward a better understanding of the potential impact of climate variability and change on the hydrology and water resources in the Philippines. Impacts of extreme events such as droughts are discussed. A preliminary study on the variability of inflow in relation to rainfall at the major dams in Luzon and the natural water reservoir of Lake Lanao is presented. Areas for future study are also mentioned.watershed

On-line Solid Phase Extraction Coupled With Liquid Chromatography Tandem Mass Spectrometry For The Determination Of Codeine In Human Plasma

A specific LC-MS/MS method was developed and validated for automated determination of codeine in human plasma, using on-line solid phase extraction (SPE) system coupled with positive ion electrospray ionization tandem mass spectrometry. The method allowed plasma direct injection onto cartridge without sample pre-treatment. Total analysis time per run was 3 min, allowing high-throughput for codeine determination. SPE on-line along a monolithic column (Chromolith Performance RP-18e, 100 mm x 4.6 mm) demonstrated to be highly effective in terms of backpressure, separation speed and peak asymmetry. Calibration curves range was linear 5.0-200 ng mL(-1). Method showed an excellent intra-day and inter-day precision ranged from 2.34 to 7.25% (CV%) as well as great intra-day and inter-day accuracy, ranging from 97.64 to 110% (RE%). SPE-LC-MS/MS method provided selectivity, accuracy, precision, fastness and high-throughput to assess codeine pharmacokinetics in human plasma samples.401252

Antioxidant Capacity and Antimicrobial Activity of Commercial Samples of Guava Leaves (\u3cem\u3ePsidium guajava\u3c/em\u3e)

Psidium guajava is a small tree native to South and Central America. Guava leaves have traditionally been used for treating different illnesses. These benefits can be attributed to phenolics and flavonoids produced by guava. The chemical composition of guava leaf extracts was correlated with biological activity. Total phenolics, total flavonoids, ABTS/DPPH, TZM-bl, plaque reduction, XTT, spectrophotometric and Kirby-Bauer assays were used to test phenols, flavonoids, antioxidant properties, antiviral activity, cytotoxicity, and antibacterial activity, respectively. The median cytotoxicity concentration and half-maximal effective concentration values were obtained in order to determine antiviral selectivity against human immunodeficiency virus type 1 and herpes simplex virus type 1. Antibacterial activity against Escherichia coli and Bacillus subtilis were evaluated using a spectrophotometric assay and Kirby-Bauer test. The guava leaf extracts had a high phenol (0.8 to 2.1 GAE mg/mL) and flavonoid (62.7 to 182.1 Rutin Eq mg/g DW) content that correlated with high antioxidant capacity and selective antiviral activity (therapeutic index values above 10). Results of antibacterial tests indicated that the extracts have activity against gram-negative and gram-positive bacteria