11 research outputs found

    A deep-learning model to continuously predict severe acute kidney injury based on urine output changes in critically ill patients

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    BACKGROUND: Acute Kidney Injury (AKI), a frequentcomplication of pateints in theIntensive Care Unit (ICU), is associated with a high mortality rate. Early prediction of AKI is essential in order to trigger the use of preventive careactions.METHODS: The aim of this study was to ascertain the accuracy of two mathematical analysis models in obtaining a predictive score for AKI development. A deep learning model based on a urine output trends was compared with a logistic regression analysis for AKI prediction in stages 2 and 3 (defined as the simultaneous increase of serum creatinine and decrease of urine output, according to the Acute Kidney Injury Network (AKIN) guidelines). Two retrospective datasets including 35,573 ICU patients were analyzed. Urine output data were used to train and test the logistic regression and the deep learning model.RESULTS: The deep learning model definedan area under the curve (AUC) of 0.89 (±0.01), sensitivity=0.8 and specificity=0.84, which was higher than the logistic regression analysis. The deep learning model was able to predict 88% of AKI cases more than 12h before their onset: for every 6 patients identified as being at risk of AKI by the deep learning model, 5 experienced the event. On the contrary, for every 12 patients not considered to be at risk by the model, 2 developed AKI.CONCLUSION: In conclusion, by using urine output trends, deep learning analysis was able to predict AKI episodes more than 12h in advance, and with a higher accuracy than the classical urine output thresholds. We suggest that this algorithm could be integrated inthe ICU setting to better manage, and potentially prevent, AKI episodes

    Investigating the kinematics of the unstable slope of BarberĂ  de la Conca (Catalonia, Spain) and the effects on the exposed facilities by GBSAR and multi-source conventional monitoring

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    The paper presents a multi-source approach tailored for the analysis of ground movements affecting the village of BarberĂ  de la Conca (Tarragona, Catalonia, Spain), where cracks on the ground and damage of different severity to structures and infrastructure was recorded. For this purpose, monitoring of ground displacements performed by topographic survey, geotechnical monitoring and remote sensing techniques (ground-based synthetic aperture radar, GBSAR) are combined with multi-temporal damage surveys and monitoring of cracks (crackmeters) to get an insight into the kinematics of the urban slope. The obtained results highlight the correspondence between the monitoring data and the effects on the exposed facilities induced by ground displacements, which seem to occur predominantly in the horizontal plane with diverging directions (northward and southward) from the main ground fracture crossing the centre of the village. The case study stands as a further contribution to fostering this kind of integrated approaches that via cross-validations can improve data reliability as well as enrich datasets for slope instability recognition and analysis, which are crucial to plan risk mitigation works
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