A theory-based approach to understanding condom errors and problems reported by men attending an STI clinic

The official published version can be accessed from the link below - Copyright @ 2008 Springer VerlagWe employed the information–motivation–behavioral skills (IMB) model to guide an investigation of correlates for correct condom use among 278 adult (18–35 years old) male clients attending a sexually transmitted infection (STI) clinic. An anonymous questionnaire aided by a CD-recording of the questions was administered. Linear Structural Relations Program was used to conduct path analyses of the hypothesized IMB model. Parameter estimates showed that while information did not directly affect behavioral skills, it did have a direct (negative) effect on condom use errors. Motivation had a significant direct (positive) effect on behavioral skills and a significant indirect (positive) effect on condom use errors through behavioral skills. Behavioral skills had a direct (negative) effect on condom use errors. Among men attending a public STI clinic, these findings suggest brief, clinic-based, safer sex programs for men who have sex with women should incorporate activities to convey correct condom use information, instill motivation to use condoms correctly, and directly enhance men’s behavioral skills for correct use of condoms

Concerted reductive coupling of an alkyl chloride at Pt(IV)

Oxidation of a doubly cyclometallated platinum(II) complex results in two isomeric platinum(IV) complexes. Whereas the trans isomer is robust, being manipulable in air at room temperature, the cis isomer decomposes at −20 °C and above. Reductive coupling of an alkyl chloride at the cis isomer gives a new species which can be reoxidised. The independence of this coupling on additional halide rules out the reverse of an SN2 reaction, leaving a concerted process as the only sensible reaction pathway

Southwest Research Institute assistance to NASA in biomedical areas of the technology utilization program Final report, 1 Nov. 1967 - 30 Nov. 1968

Southwest Research Institute activities in technology utilization program in biomedical areas, Nov. 1967 - Nov. 196

Satellite Temperature Monitoring and Prediction System

This system used data from the Geostationary Operational Environmental Satellite (GOES) to derive and display surface temperature distributions throughout peninsular Florida on cold nights. These distributions, in conjunction with ground meteorological data, provide inputs to mathematical models which predict temperature distributions up to 10 hours in advance. This system is being developed by scientists at the University of Florida Institute of Food and Agricultural Sciences (IFAS) in cooperation with and sponsored by the National Aeronautics and Space Administration (NASA), Kennedy Space Center (KSC) supported by the National Oceanic and Atmospheric Administration (NOAA), National Weather Service (NWS). The system has been installed in the NWS facility at Ruskin, Florida, and has been operated in an experimental mode by NWS forecasters for the past three winters. The primary purpose of the system is to provide a tool for use by NWS weather forecasters to permit more timely more complete and more accurate temperature data for use by agricultural interests on nights when their crops are threatened by a cold wave. This better information can result in more timely decisions in the use of frost protection techniques thus deriving substantial benefits in terms of cost savings and crops protected and salvaged

A three-dimensional current meter for estuarine applications

A curr ent meter that is capable of measuring the high-frequency fluctuations of the three-dimensional velocity vector has been developed. The meter works on a doppler-shift principle. At high velocities, the meter has been shown to have an accuracy of better than 3%

Deformation of vortex patches by boundaries

The deformation of two-dimensional vortex patches in the vicinity of fluid boundaries is investigated. The presence of a boundary causes an initially circular patch of uniform vorticity to deform. Sufficiently far away from the boundary, the deformed shape is well approximated by an ellipse. This leading order elliptical deformation is investigated via the elliptic moment model of Melander, Zabusky & Styczek [M. V. Melander, N. J. Zabusky & A. S. Styczek, J. Fluid. Mech., 167, 95 (1986)]. When the boundary is straight, the centre of the elliptic patch remains at a constant distance from the boundary, and the motion is integrable. Furthermore, since the straining flow acting on the patch is constant in time, the problem is that of an elliptic vortex patch in constant strain, which was analysed by Kida [S. Kida, J. Phys. Soc. Japan, 50, 3517 (1981)]. For more complicated boundary shapes, such as a square corner, the motion is no longer integrable. Instead, there is an adiabatic invariant for the motion. This adiabatic invariant arises due to the separation in times scales between the relatively rapid time scale associated with the rotation of the patch and the slower time scale associated with the self-advection of the patch along the boundary. The interaction of a vortex patch with a circular island is also considered. Without a background flow, conservation of angular impulse implies that the motion is again integrable. The addition of an irrotational flow past the island can drive the patch towards the boundary, leading to the possibility of large deformations and breakup.Comment: 19 pages, 16 figure

A Natural Plasmid Uniquely Encodes Two Biosynthetic Pathways Creating a Potent Anti-MRSA Antibiotic

Background Understanding how complex antibiotics are synthesised by their producer bacteria is essential for creation of new families of bioactive compounds. Thiomarinols, produced by marine bacteria belonging to the genus Pseudoalteromonas, are hybrids of two independently active species: the pseudomonic acid mixture, mupirocin, which is used clinically against MRSA, and the pyrrothine core of holomycin. Methodology/Principal Findings High throughput DNA sequencing of the complete genome of the producer bacterium revealed a novel 97 kb plasmid, pTML1, consisting almost entirely of two distinct gene clusters. Targeted gene knockouts confirmed the role of these clusters in biosynthesis of the two separate components, pseudomonic acid and the pyrrothine, and identified a putative amide synthetase that joins them together. Feeding mupirocin to a mutant unable to make the endogenous pseudomonic acid created a novel hybrid with the pyrrothine via “mutasynthesis” that allows inhibition of mupirocin-resistant isoleucyl-tRNA synthetase, the mupirocin target. A mutant defective in pyrrothine biosynthesis was also able to incorporate alternative amine substrates. Conclusions/Significance Plasmid pTML1 provides a paradigm for combining independent antibiotic biosynthetic pathways or using mutasynthesis to develop a new family of hybrid derivatives that may extend the effective use of mupirocin against MRSA

Adapting SAM for CDF

The CDF and D0 experiments probe the high-energy frontier and as they do so have accumulated hundreds of Terabytes of data on the way to petabytes of data over the next two years. The experiments have made a commitment to use the developing Grid based on the SAM system to handle these data. The D0 SAM has been extended for use in CDF as common patterns of design emerged to meet the similar requirements of these experiments. The process by which the merger was achieved is explained with particular emphasis on lessons learned concerning the database design patterns plus realization of the use cases.Comment: Talk from the 2003 Computing in High Energy and Nuclear Physics (CHEP03), La Jolla, Ca, USA, March 2003, 4 pages, pdf format, TUAT00

The State of Self-Organized Criticality of the Sun During the Last 3 Solar Cycles. I. Observations

We analyze the occurrence frequency distributions of peak fluxes $P$, total fluxes $E$, and durations $T$ of solar flares over the last three solar cycles (during 1980--2010) from hard X-ray data of HXRBS/SMM, BATSE/CGRO, and RHESSI. From the synthesized data we find powerlaw slopes with mean values of $\alpha_P=1.72\pm0.08$ for the peak flux, $\alpha_E=1.60\pm0.14$ for the total flux, and $\alpha_T=1.98\pm0.35$ for flare durations. We find a systematic anti-correlation of the powerlaw slope of peak fluxes as a function of the solar cycle, varying with an approximate sinusoidal variation $\alpha_P(t)=\alpha_0+\Delta \alpha \cos{[2\pi (t-t_0)/T_{cycle}]}$, with a mean of $\alpha_0=1.73$, a variation of $\Delta \alpha =0.14$, a solar cycle period $T_{cycle}=12.6$ yrs, and a cycle minimum time $t_0=1984.1$. The powerlaw slope is flattest during the maximum of a solar cycle, which indicates a higher magnetic complexity of the solar corona that leads to an overproportional rate of powerful flares.Comment: subm. to Solar Physic