Single-Ion Magnets Based on Mononuclear Cobalt(II) Complexes with Sulfadiazine

The already reported monomeric complex Co(SDZ)2bpy (1) and the new ternary complex Co(SDZ)2(6MQ)2 (2) (SDZ = sulfadiazine, bpy = 2,2′‐bipyridine, and 6MQ = 6‐methoxyquinoline) have been synthesized in order to study their magnetic properties. X‐ray diffraction studies indicate that in both compounds the SDZ acts as a bidentate ligand coordinating through the sulfonamide and the pyrimidine N atoms giving rise to a CoN6 coordination sphere. The complexes have been characterized based on elemental analyses, FTIR, UV/Vis spectroscopy, and thermogravimetric analysis (TGA, only for 2). Compounds 1 and 2 have been characterized magnetically, and they show slow relaxation of the magnetization below 9 and 6 K, respectively.Centro de Química InorgánicaInstituto de Física La Plat

Crystal structure, physicochemical properties, Hirshfeld surface analysis and antibacterial activity assays of transition metal complexes of 6-methoxyquinoline

Five monomeric complexes of Co(ii), Cu(ii), Ni(ii), Zn(ii) and Ag(i) with 6-methoxyquinoline (6-MeOQ) as ligand have been prepared, and their crystal structures have been determined by single X-ray diffractions. The Cu(ii), Ni(ii) and Zn(ii) complexes are formulated as M(6-MeOQ) 2 Cl 2 , completing MN 2 Cl 2 coordination spheres. On the other hand, Co(ii) and Ag(i) compounds are ionic with formulae [Ag(6-MeOQ) 2 ] + NO 3 - and H(6-MeOQ) + [Co(6-MeOQ)Cl 3 ] - (where H(6-MeOQ) + is the protonated ligand). Hirshfeld surface analysis was employed to study the intermolecular interactions in the crystal lattices and from these studies it was found that π-stacking contacts play an important role. Besides, the complexes have been characterized by FTIR, UV-visible and emission spectroscopies. The singlet oxygen production and fluorescence quantum yields were measured for all the complexes employing steady-state methodologies. Finally, the antibacterial activity of the complexes was screened against both Gram-positive and Gram-negative bacteria.Fil: Villa Perez, Cristian. Facultad de Ciencias Exactas, Universidad Nacional de la Plata; ArgentinaFil: Ortega, I.C.. Universidad Nacional de Colombia; ColombiaFil: Vélez Macías, Andrea. Universidad Nacional de Colombia; ColombiaFil: Payán, A. M.. Universidad Nacional de Colombia; ColombiaFil: Echeverría, Gustavo Alberto. Facultad de Ciencias Exactas, Universidad Nacional de la Plata; ArgentinaFil: Soria, Delia Beatriz. Facultad de Ciencias Exactas, Universidad Nacional de la Plata; ArgentinaFil: Valencia Uribe, Gloria Cristina. Universidad Nacional de Colombia; Colombi

Crystal structure, physicochemical properties, Hirshfeld surface analysis and antibacterial activity assays of transition metal complexes of 6-methoxyquinoline

Five monomeric complexes of Co(ii), Cu(ii), Ni(ii), Zn(ii) and Ag(i) with 6-methoxyquinoline (6-MeOQ) as ligand have been prepared, and their crystal structures have been determined by single X-ray diffractions. The Cu(ii), Ni(ii) and Zn(ii) complexes are formulated as M(6-MeOQ) 2 Cl 2 , completing MN 2 Cl 2 coordination spheres. On the other hand, Co(ii) and Ag(i) compounds are ionic with formulae [Ag(6-MeOQ) 2 ] + NO 3 - and H(6-MeOQ) + [Co(6-MeOQ)Cl 3 ] - (where H(6-MeOQ) + is the protonated ligand). Hirshfeld surface analysis was employed to study the intermolecular interactions in the crystal lattices and from these studies it was found that π-stacking contacts play an important role. Besides, the complexes have been characterized by FTIR, UV-visible and emission spectroscopies. The singlet oxygen production and fluorescence quantum yields were measured for all the complexes employing steady-state methodologies. Finally, the antibacterial activity of the complexes was screened against both Gram-positive and Gram-negative bacteria.Centro de Química InorgánicaInstituto de Física La Plat

Lost in translation? Reflexiones sobre la puesta en marcha de programas bilingües en grados de informática

Bien sea por una política institucional de internacionalización, o bien por proporcionar una oferta educativa adecuada a los estudiantes que han cursado gran parte de sus estudios en inglés, las instituciones de educación superior nacionales se han enfrentado a la implantación de enseñanzas bilingües dentro de sus programas de grado o máster (o están en ello). Sin embargo, la puesta en marcha de estos programas presenta riesgos y problemas que van mucho más allá de la mera traducción de contenidos al inglés. En este artículo, los autores presentan una serie de reflexiones y algunas estrategias derivadas de los resultados parciales de un proyecto de innovación relacionada con la adaptación de asignaturas al inglés dentro de un grado de informática.Due to the implementation of an internationalization policy or just providing their home students (who might have been using English in their previous studies) with a proper education, national higher education institutions are dealing with the introduction of bilingual education in their undergraduate and postgraduate levels. However, the implementation of these foreign language educational programs entail risks and problems which go beyond the simple translation of teaching materials into English. In this paper, the authors present a series of reflections and some recommended strategies as a result of the preliminary findings of an innovation project related to the adaptation of subjects to English in a Computer Science degree

Ecological networks: delving into the architecture of biodiversity

In recent years, the analysis of interaction networks has grownpopular as a framework to explore ecological processes and the relationships between community structure and its functioning. The field has rapidly grown from its infancy to a vibrant youth, as reflected in the variety and quality of the discussions held at the first international symposium on Ecological Networks in Coimbra—Portugal (23–25 October 2013). The meeting gathered 170 scientists from 22 countries, who presented data from a broad geographical range, and covering all stages of network analyses, from sampling strategies to effective ways of communicating results, presenting new analytical tools, incorporation of temporal and spatial dynamics, new applications and visualization tools.1 During the meeting it became evident that while many of the caveats diagnosed in early network studies are successfully being tackled, new challenges arise, attesting to the health of the discipline.This work was financially supported by the Marie Curie Career Integration grant no. 2012-321794-SEEDS

IL28B gene polymorphism rs12979860, but not rs8099917, contributes to the occurrence of chronic HCV infection in uruguayan patients

Background: Host single-nucleotide polymorphisms (SNPs) near the interleukin 28B (IL28B) locus are associated with sustained virological response to antiviral therapy and with spontaneous Hepatitis C Virus (HCV) clearance. Prevalence of these SNPs varies depending on ethnicity. The impact of IL28B SNPs in HCV-infected patients is currently unknown in Uruguay. Therefore, the aim of this study was to evaluate and compare the distribution of polymorphisms in the IL28B gene (rs12979860 and rs8099917) among HCV-infected patients and healthy individuals in Uruguay and thus assess their possible association with the establishment of HCV infection. Methods: DNA was recovered from 92 non-infected individuals and 78 HCV-infected patients and SNPs were determined by RFLP and allelic discrimination by real-time PCR. Results: The distribution of rs12979860 genotypes for the infected population was 29.5%-CC, 47.4%-CT and 23.1%-TT and for the control group 45.7,% 42.4% and 11.9,% respectively. Prevalence in both infected and uninfected individuals is similar to that reported in other countries with admixed populations. The distribution of rs8099917 genotypes for the infected population was 57.7%-TT, 27.2%-TG and 14.1%-GG and for the control group 60.9,% 33.7% and 5.4,% respectively. The comparison of rs12979860 genotype distribution between the two populations evidenced a higher prevalence of the favourable genotype (CC) in the uninfected control group (p < 0.05). Additionally, results generated using logistic regression analysis show that individuals carrying rs12979860-TT or CT genotypes have a higher likelihood of developing chronic hepatitis upon infection with HCV, when compared to CC carriers, considering rs8099917 genotype as constant. Conclusion: Patients with HCV infection have a statistically significant lower prevalence of the favourable rs12979860 genotype when compared to uninfected individuals; therefore we can establish that only IL28B rs12979860-CT and TT genotypes seem to contribute to the occurrence of chronic HCV infection in the cohort of Uruguayan population studied. Considering that a trend towards a higher frequency of "good" response genotypes was observed in responder patients, we believe that IL28B rs12979860 genotyping could be a useful tool for predicting different therapies outcome, including in the DAA era

Análisis de la interacción Mar-Tierra como base de la gestión de zonas costeras: estudio comparativo entre Argentina y Uruguay

La tierra y el mar están inherentemente conectados a través de múltiples y complejas interacciones socioecológicas que influyen en el sustento y bienestar de las personas. Mediante una aproximación metodológica interdisciplinaria y el análisis de un caso regional comparativo entre la costa Sur de Mar del Plata (Argentina) y la costa Oeste de Montevideo (Uruguay), se plantean la identificación de usos terrestres y marinos con implicancias mutuas, registrar estas interacciones analizando su grado de compatibilidad y, comparar analíticamente los resultados. Ambas áreas de estudio presentaron similares usos y actividades T- M, así como la proporción de interacciones positivas y conflictivas. El análisis de los aspectos comunes permitió identificar que los conflictos medios se relacionan con la coexistencia espacial y temporal de usos y actividades costero-marinas. Las diferencias, se manifestaron por actividades desarrolladas en un área y no en otra, por la modalidad y tipología de desarrollo o porque no se registraron temporal y espacialmente interacciones comunes. La investigación aportó a la construcción de consensos conceptuales y metodológicos sobre las interacciones T-M-T. Estas fueron aplicadas respectivamente en tierra y en el mar, en ambos estudios de casos piloto.Land and sea are inherently connected through multiple and complex socioecological interactions that influence people's livelihoods and well-being. Through an interdisciplinary methodological approach and the analysis of a comparative regional case between the south coast of Mar del Plata (Argentina) and the west coast of Montevideo (Uruguay), the aim is to identify land and marine uses with mutual implications, to record these interactions by analyzing their degree of compatibility, and to analytically compare the results. Both study areas presented similar uses and T-M activities, as well as the proportion of positive and conflicting interactions. The analysis of the common aspects allowed us to identify that the average conflicts are related to the spatial and temporal coexistence of coastal-marine uses and activities. The differences were manifested by activities developed in one area and not in another, by the modality and typology of development or because common interactions were not recorded temporally and spatially. The research contributed to the construction of conceptual and methodological consensus on T-M-T interactions. These were applied respectively on land and at sea, in both pilot case studies.Fil: Echeverría, Luciana. Universidad de la República; UruguayFil: Verón, Eleonora Marta. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Mar del Plata; ArgentinaFil: Medina, Mercedes. Universidad de la República; UruguayFil: Socrate, Juliana. Universidad Nacional de Mar del Plata. Facultad de Humanidades. Departamento de Geografía. Centro de Investigaciones Geográficas Socio-ambientales; ArgentinaFil: Sanchez, M. Victoria. Universidad de la República; UruguayFil: Garcia, Monica Cristina. Universidad Nacional de Mar del Plata. Facultad de Humanidades. Departamento de Geografía. Centro de Investigaciones Geográficas Socio-ambientales; ArgentinaFil: Fernandez, Melisa. Universidad de la República; UruguayFil: Pérez Brum, William. Universidad de la República; UruguayFil: Camiolo, Martina Daniela. Universidad Nacional de Mar del Plata. Facultad de Humanidades; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Mar del Plata; ArgentinaFil: Vallvé, Elena. Universidad de la República; UruguayFil: Jaureguizar, Andrés Javier. Provincia de Buenos Aires. Gobernación. Comisión de Investigaciones Científicas; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Caporale, Marcela. Universidad de la República; UruguayFil: Machain, Tiago. Universidad de la República; Urugua