Guide of principles in main dog and cat skin’s afections topical aplications

The report is an attempt to remember of the updated general principles in the main dermatologic affects topical applications’ in in dog and cat. Initially are presented: general principles about drug topic formulation’s application, with the describing of skin’s anatomical bases and functions, active substance’s physic-chemicalproprieties, factors that affects transdermal passage, methods of transdermal amplification. Also are presented: characteristics of dog and cat’s skin, skin’s specific vascularisation, ecology and histochemy. In the last chapter are presented the main known dermatologic entities in dog and cat

A language for the integration of web sources

This is an electronic version of the paper presented at the IADIS International Conference WWW / INTERNET 2006, held in Murcia on 2006This paper presents a language for the creation of data sources in mediation systems through navigation in web sites. The general idea of the language is to “thread together,” so to speak, existing systems that parse and analyze single web pages into a navigation procedure spanning several pages of a web site, pages from different web sites, or web pages and other data repositories

The effect of glucosamine, chondroitin and harpagophytum procumbens on femoral hyaline cartilage thickness in patients with knee osteoarthritis– An MRI versus ultrasonography study

Background: the evaluation of cartilage thickness has become possible with new techniques such as musculoskeletal ultrasonography (US) and magnetic resonance imagining (MRI), making the evaluation of the treatment response and the progression of the disease more accurate. Objective: to evaluate the efficacy of a Symptomatic Slow Acting Drug for Osteoarthritis using both US and MRI for measuring cartilage thickness at baseline and after 1 year. Methods: The study included the clinical evaluation of 20 patients at baseline, at 6 and 12 months as well as imaging exams (US and MRI) at baseline and after 1 year. Measurements were performed in both knees, in lateral and medial condyles, and in the intercondylar area. After the baseline visit, patients underwent a SYSADOA treatment which included Harpagophytum procumbens (HPc) administered on a daily basis, in a specific regimen. Results and discussions: The US examination permitted the detailed evaluation of the femoral hyaline cartilage thickness, with statistically significant differences before and after treatment at the level of the medial compartment, both in the dominant (1.59±0.49 vs. 1.68±0.49, p=0.0013) and non-dominant knee (1.73±0.53 vs. 1.79±0.52, p=0.0106). The US and the MRI correlated well (r=0.63) and showed no radiographic progression in knee osteoarthritis after one year of treatment with specific SYSADOA. Moreover, the US showed improvement in the cartilage thickness of the medial compartment. Conclusions: The combination with HPc could increase the delay in the radiographic progression of the knee osteoarthritis, with improvement of femoral hyaline cartilage thickness in the medial and lateral compartment. The US might be an important tool in OA evaluation and monitoring

Молочное питание и ее связь с состоянием здоровья грудных детей, госпитализированных в больнице уезда Дробета Турну-Северин (частный случай)

Universitatea de Medicină şi Farmacie Victor Babeş, Timişoara, Disciplina Igiena, Spitalul Judeţean Drobeta Turnu-Severin, secţia Pediatrie, Conferința știinţifico-practică naţionale cu participare internaţională ”Probleme actuale ale prevenirii și controlului bolilor netransmisibile” Chișinău, 18-20 iunie 2015In the performed case-study at the Paediatric Department of the Turnu-Severin County Hospital, along april-october 2014 we aimed at investigating development, the used milk formulas and diagnosed patholgy at admission in hospital of the 65 infants (44.4% boys and 55.6% girls, aged 0-1 year), and the relation between milk formulas and diagnosed diseases. An increased frequency of cow milk administration (26.3%), an increased frequency of anaemia (55.4%) and a possible relation cow milk consumption – anaemia (χ2 =29.28, S=0.004) were registered. В отделении педиатрии больницы уезда ТурнуСеверин, в апреле-октябре месяцы 2014 г., проводили исследование взаимосвязи вида молока, использованного в питании 65 грудных детей (44,4% мальчиков и 5015,6% девочек в возрасте 0-1 год), и диагносцированной патологией. Зарегистрировано частое использование в питании детей коровьего молока (26,3%), высокая частота анемий (55.4%) и определенная взаимосвязь между питанием детей коровьим молоком и анемиями (χ2 =29.28, S=0.004)

Nitrite binding to globins: linkage isomerism, EPR silence and reductive chemistry

The nitrite adducts of globins can potentially bind via O- or N- linkage to the heme iron. We have used EPR (electron paramagnetic resonance) and DFT (density functional theory) to explore these binding modes to myoglobin and hemoglobin. We demonstrate that the nitrite adducts of both globins have detectable EPR signals; we provide an explanation for the difficulty in detecting these EPR features, based on uniaxial state considerations. The EPR and DFT data show that both nitrite linkage isomers can be present at the same time and that the two isomers are readily interconvertible in solution. The millisecond-scale process of nitrite reduction by Hb is investigated in search of the elusive Fe(II)-nitrite adduct