359 research outputs found

    The effect of selected academic development programmes on the academic performance of academic development students at a South African university : an empirical study.

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    Includes abstract.Includes bibliographical references.The case studies that make up this thesis cover the three largest academic development programmes at the University of Cape Town. A variety of statistical methods are used to estimate the effect of educational interventions in selected first- and second-year academic development courses on the academic performance of academic development students in these courses and through to graduation, relative to mainstream students. In general, research in this area in South Africa and internationally has been characterised by small sample sizes and a lack of statistical rigour. Few studies control for the range of independent variables that can affect students’ academic performance, in addition to the academic development programme or course, and the great majority ignore the sampleselection problem that arises in the selection of students for academic development and mainstream programmes. The theoretical rationale underpinning this thesis is informed by the postpositivist and evidence-based approaches to empirical investigation. Demographic, academic and other data for some 9000 students for the years 1999?2005 was obtained from the university’s data base and academic departments. Statistical techniques including multivariate analysis and propensity score matching are used in an attempt to finesse the problems associated with the use of non-experimental data as students are selected into different courses and programmes

    Confronting an identity crisis - how to "brand" systems engineering

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    Systems Engineering is not a new discipline; the term has been in use since World War II. Yet, while there has been no shortage of definitions of the term over the years (not all of which are consistent), there is little consensus on the scope of Systems Engineering. This is particularly true in relation to other overlapping disciplines such as System Dynamics, Operations Research, Industrial Engineering, Project Management, Soft Systems Methodology, Specialist Engineering, and Control Theory, which share many of the origins and techniques of Systems Engineering. This paper presents a landscape of disciplines and suggests that INCOSE should “brand” Systems Engineering strategically, defining explicitly its position within this landscape including its points of parity (overlaps) and points of difference with other disciplines. Actively branding Systems Engineering will broaden its appeal and attract more interest from stakeholders outside the current Systems Engineering community. INCOSE’s “market share” relative to its biggest systems competitor—Project Management—is falling, so even though INCOSE membership is rising, more needs to be done to promote the profession

    The Beijing Summer Olympic Games: Decisions from the CAS and IOC

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    This article reviews the Beijing Olympic Games cases heard by the Court of Arbitration for Sport (CAS) Appeal Division before and after the Olympic Games and the Ad-hoc Division (AHD) in Beijing, together with pertinent IOC Executive Board doping and disciplinary decisions. The discussion is in chronological order dealing first with Olympic-related cases that were heard by the ordinary and appeal divisions in Lausanne prior to the AHD taking jurisdiction of Olympic matters. Those cases are followed by appeals heard by the appeal division while the AHD took jurisdiction over Olympic matters in Beijing. A discussion of the decisions made by the AHD and IOC during the pre-games lead-up to the opening ceremonies then follows, after which attention is turned to those cases that arose during the Olympic Games and were disposed of by the AHD and IOC at the Games. Finally, the appeals made to the CAS after the close of the 2008 Beijing Olympic Summer Games but related thereto will be reviewed

    Neural Coding of Movement Direction in the Healthy Human Brain

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    Neurophysiological studies in monkeys show that activity of neurons in primary cortex (M1), pre-motor cortex (PMC), and cerebellum varies systematically with the direction of reaching movements. These neurons exhibit preferred direction tuning, where the level of neural activity is highest when movements are made in the preferred direction (PD), and gets progressively lower as movements are made at increasing degrees of offset from the PD. Using a functional magnetic resonance imaging adaptation (fMRI-A) paradigm, we show that PD coding does exist in regions of the human motor system that are homologous to those observed in non-human primates. Consistent with predictions of the PD model, we show adaptation (i.e., a lower level) of the blood oxygen level dependent (BOLD) time-course signal in M1, PMC, SMA, and cerebellum when consecutive wrist movements were made in the same direction (0° offset) relative to movements offset by 90° or 180°. The BOLD signal in dorsolateral prefrontal cortex adapted equally in all movement offset conditions, mitigating against the possibility that the present results are the consequence of differential task complexity or attention to action in each movement offset condition

    Validation of key behaviourally based mental health diagnoses in administrative data: suicide attempt, alcohol abuse, illicit drug abuse and tobacco use

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    <p>Abstract</p> <p>Background</p> <p>Observational research frequently uses administrative codes for mental health or substance use diagnoses and for important behaviours such as suicide attempts. We sought to validate codes (<it>International Classification of Diseases, 9<sup>th </sup>edition, clinical modification </it>diagnostic and E-codes) entered in Veterans Health Administration administrative data for patients with depression versus a gold standard of electronic medical record text ("chart notation").</p> <p>Methods</p> <p>Three random samples of patients were selected, each stratified by geographic region, gender, and year of cohort entry, from a VHA depression treatment cohort from April 1, 1999 to September 30, 2004. The first sample was selected from patients who died by suicide, the second from patients who remained alive on the date of death of suicide cases, and the third from patients with a new start of a commonly used antidepressant medication. Four variables were assessed using administrative codes in the year prior to the index date: suicide attempt, alcohol abuse/dependence, drug abuse/dependence and tobacco use.</p> <p>Results</p> <p>Specificity was high (≥ 90%) for all four administrative codes, regardless of the sample. Sensitivity was ≤75% and was particularly low for suicide attempt (≤ 17%). Positive predictive values for alcohol dependence/abuse and tobacco use were high, but barely better than flipping a coin for illicit drug abuse/dependence. Sensitivity differed across the three samples, but was highest in the suicide death sample.</p> <p>Conclusions</p> <p>Administrative data-based diagnoses among VHA records have high specificity, but low sensitivity. The accuracy level varies by different diagnosis and by different patient subgroup.</p

    Tobacco use disorder and the risk of suicide mortality

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    Background and aims Tobacco use may be a risk factor for suicide mortality; however, prior research has produced equivocal findings and has been limited by relatively small sample sizes to study the rare event of suicide, as well as a lack of adjustment for other important factors, including psychiatric illness. We estimate the predictive association between tobacco use disorder and the risk of suicide mortality, adjusting for other important variables. Design A prospective cohort study. Setting The U nited S tates V eterans H ealth A dministration ( VHA ). Participants All individuals who received VHA services in fiscal year (FY) 2005 and were alive at the start of FY 2006 ( n  = 4 863 086). Measurements Tobacco use disorder was assessed via FYs 2004–05 VHA National P atient C are D atabase records. The outcome of suicide mortality was assessed during the follow‐up interval from the beginning of FY 2006 to the end of FY 2008 using N ational D eath I ndex records. Findings Of the 4 863 086 individuals in the study, 4823 died by suicide during the follow‐up interval. In the unadjusted model, tobacco use disorder was associated with an increased risk of suicide [hazard ratio (HR) = 1.88; 95% confidence interval (CI) = 1.76, 2.02]. After adjustment for model covariates, the association remained statistically significant, although attenuated (HR = 1.36, 95% CI = 1.27, 1.46). Conclusions Tobacco use disorder may confer a modest excess risk of death by suicide. Psychiatric disorders may partially explain the relationship between tobacco use disorder and suicide.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/102156/1/add12381.pd

    Early mortality experience in a large military cohort and a comparison of mortality data sources

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    <p>Abstract</p> <p>Background</p> <p>Complete and accurate ascertainment of mortality is critically important in any longitudinal study. Tracking of mortality is particularly essential among US military members because of unique occupational exposures (e.g., worldwide deployments as well as combat experiences). Our study objectives were to describe the early mortality experience of Panel 1 of the Millennium Cohort, consisting of participants in a 21-year prospective study of US military service members, and to assess data sources used to ascertain mortality.</p> <p>Methods</p> <p>A population-based random sample (n = 256,400) of all US military service members on service rosters as of October 1, 2000, was selected for study recruitment. Among this original sample, 214,388 had valid mailing addresses, were not in the pilot study, and comprised the group referred to in this study as the invited sample. Panel 1 participants were enrolled from 2001 to 2003, represented all armed service branches, and included active-duty, Reserve, and National Guard members. Crude death rates, as well as age- and sex-adjusted overall and age-adjusted, category-specific death rates were calculated and compared for participants (n = 77,047) and non-participants (n = 137,341) based on data from the Social Security Administration Death Master File, Department of Veterans Affairs (VA) files, and the Department of Defense Medical Mortality Registry, 2001-2006. Numbers of deaths identified by these three data sources, as well as the National Death Index, were compared for 2001-2004.</p> <p>Results</p> <p>There were 341 deaths among the participants for a crude death rate of 80.7 per 100,000 person-years (95% confidence interval [CI]: 72.2,89.3) compared to 820 deaths and a crude death rate of 113.2 per 100,000 person-years (95% CI: 105.4, 120.9) for non-participants. Age-adjusted, category-specific death rates highlighted consistently higher rates among study non-participants. Although there were advantages and disadvantages for each data source, the VA mortality files identified the largest number of deaths (97%).</p> <p>Conclusions</p> <p>The difference in crude and adjusted death rates between Panel 1 participants and non-participants may reflect healthier segments of the military having the opportunity and choosing to participate. In our study population, mortality information was best captured using multiple data sources.</p

    Mortality in fibromyalgia: A study of 8,186 patients over thirty-five years

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    Objective To determine if mortality is increased among patients diagnosed as having fibromyalgia. Methods We studied 8,186 fibromyalgia patients seen between 1974 and 2009 in 3 settings: all fibromyalgia patients in a clinical practice, patients participating in the US National Data Bank for Rheumatic Diseases (NDB), and patients invited to participate in the NDB who refused participation. Internal controls included 10,087 patients with osteoarthritis. Deaths were determined by multiple source communication, and all patients were also screened in the US National Death Index (NDI). We calculated standardized mortality ratios (SMRs) based on age- and sex-stratified US population data, after adjustment for NDI nonresponse. Results There were 539 deaths, and the overall SMR was 0.90 (95% confidence interval [95% CI] 0.61–1.26). Among 1,665 clinic patients, the SMR was 0.92 (95% CI 0.81–1.05). Sensitivity analyses varying the rate of NDI nonidentification did not alter the nonassociation. Adjusted for age and sex, the hazard ratio for fibromyalgia compared with osteoarthritis was 1.05 (95% CI 0.94–1.17). The standardized mortality odds ratio (OR) compared with the US general population was increased for suicide (OR 3.31, 95% CI 2.15–5.11) and for accidental deaths (OR 1.45, 95% CI 1.02– 2.06), but not for malignancy. Conclusion Mortality does not appear to be increased in patients diagnosed with fibromyalgia, but the risk of death from suicide and accidents was increased.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/79414/1/20301_ftp.pd
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