2,153 research outputs found

    Breaching Location Silos: An Exploration of social media optimisation by SMMEs in Southern Africa

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    Published ArticleThis study explores the significance of social media as e-marketplaces for advancing e-commerce for small scale, micro and medium enterprises (SMMEs) in the southern African sub-region – notably in South Africa and Zimbabwe. Evidence from the examination of extant literature and our personal observations reveal that when properly harnessed as e-marketplaces, social media platforms, especially those that are compatible with mobile devices (i.e. smart mobile phones, tablets and notebooks), have tremendous e-commerce potential to enhance brand awareness, market growth, and market share for firms, thereby augmenting and expediting the management of customer relationships and brand loyalty. These benefits have the potential to trigger innovative marketing, brand positioning and creativity for SMMEs in South Africa and Zimbabwe. The main theoretical contribution of this study is the development of a conceptual model of social media that promotes SMME growth especially considering the large percentage of youth with a large appetite for new technology. Therefore, active engagement on social media could breach (the current) location silos," by tapping into the diaspora market

    Ydj1 governs fungal morphogenesis and stress response, and facilitates mitochondrial protein import via Mas1 and Mas2

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    We thank Zhen-Yuan Lin for help in the preparation of the AP-MS samples, and Cathy Collins for technical assistance. MDL is supported by a Sir Henry Wellcome Postdoctoral Fellowship (Wellcome Trust 096072), LEC is supported by a Canada Research Chair in Microbial Genomics and Infectious Disease and by Cana-dian Institutes of Health Research (CIHR) Grants MOP-119520 and MOP-86452. OK is supported by National Insti-tutes of Health grant 5R01GM108975. A-CG is supported by a CIHR Foundation Grant (FDN143301), Genome Cana-da Genomics Innovation Network (GIN) Node and Tech-nical Development Grants, and a Canada Research Chair in Functional Proteomics. J-PL was supported by a TD Bank Health Research Fellowship at the Lunenfeld-Tanenbaum Research Institute and by a Scholarship for the Next Gen-eration of Scientists from the Cancer Research Society. JLX is supported by a CIHR – Frederick Banting and Charles Best Canada Graduate Scholarship. The funding agencies had no role in the study design, data collection and inter-pretation, or the decision to submit the work for publication.Peer reviewedPublisher PD

    Further investigations on the proliferative response of mouse bladder epithelium to 4-ethyl-sulphonylnaphthalene-1-sulphonamide.

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    4-ETHYLSULPHONYLNAPHTHALENE-1-SULPHONAMIDE (ENS*) induces hyperplasia of the bladder epithelium on administration to rats (Paget, 1958) and mice (Sen Gupta, 1962). Bladder tumours result from prolonged feeding of ENS to mice (Clayson and Bonser, 1965; Clayson, Pringle and Bonser, 1967). Hyperplasia is more severe and tumcours are more frequent in female than in male mice. The acute response to a single oral dose of ENS has been studied in some detail (Clayson et al., 1967; Lawson, Dzhioev, Lewis and Clayson, 1968; Levi, Cowen and Cooper, 1969). An increase in DNA synthesis, in the normally quiescent bladder epithelium, is induced at about 16 hours after the administration of the chemical, rises to a maximum at 30-36 hours and thereafter slowly declines. RNA synthesis, necessary for the increase in enzymes for DNA synthesis, occurs during the lag phase. Detailed histopathological, autoradiographic and stathmokinetic investigations show that DNA synthesis and subsequent mitosis occur in every cell layer and involve cells of all ploidies in this epithelium, in contradistinction to the behaviour of other multilayered epithelia in which DNA synthesis and mitosis i

    Laser Tracker Utilization Methodology in Measuring Truth Trajectories for INS Testing on 6 Degree of Freedom Table at the Marshall Space Flight Center's Contact Dynamics Simulation Laboratory with Lessons Learned

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    When performing Inertial Navigation System (INS) testing at the Marshall Space Flight Center's (MSFC) Contact Dynamics Simulation Laboratory (CDSL) early in 2017, a Leica Geosystems AT901 Laser Tracker system (LLT) measured the twist & sway trajectories as generated by the 6 Degree Of Freedom (6DOF) Table in the CDSL. These LLT measured trajectories were used in the INS software model validation effort. Several challenges were identified and overcome during the preparation for the INS testing, as well as numerous lessons learned. These challenges included determining the position and attitude of the LLT with respect to an INS-shared coordinate frame using surveyed monument locations in the CDSL and the accompanying mathematical transformation, accurately measuring the spatial relationship between the INS and a 6DOF tracking probe due to lack of INS visibility from the LLT location, obtaining the data from the LLT during a test, determining how to process the results for comparison with INS data in time and frequency domains, and using a sensitivity analysis of the results to verify the quality of the results. While many of these challenges were identified and overcome before or during testing, a significant lesson on test set-up was not learned until later in the data analysis process. It was found that a combination of trajectory-dependent gimbal locking and environmental noise introduced non-negligible noise in the angular measurements of the LLT that spanned the evaluated frequency spectrum. The lessons learned in this experiment may be useful for others performing INS testing in similar testing facilities

    Planar Graph Coloring with Forbidden Subgraphs: Why Trees and Paths Are Dangerous

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    We consider the problem of coloring a planar graph with the minimum number of colors such that each color class avoids one or more forbidden graphs as subgraphs. We perform a detailed study of the computational complexity of this problem. We present a complete picture for the case with a single forbidden connected (induced or non-induced) subgraph. The 2-coloring problem is NP-hard if the forbidden subgraph is a tree with at least two edges, and it is polynomially solvable in all other cases. The 3-coloring problem is NP-hard if the forbidden subgraph is a path, and it is polynomially solvable in all other cases. We also derive results for several forbidden sets of cycles
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