PROJECT STATUS TRACKING VIA INTEGRATED INTERFACE

A technique is proposed for assisting members of a project group in managing a project through a cloud-based content platform. A project synchronization service may detect an action associated with a project group has been performed using an applicable platform application. A status update reflecting the performed action may be generated. The status update may be published to a project feed, where the project feed is accessible to each user of the project group

Simulation and Analyses of Multi-Body Separation in Launch Vehicle Staging Environment

The development of methodologies, techniques, and tools for analysis and simulation of multi-body separation is critically needed for successful design and operation of next generation launch vehicles. As a part of this activity, ConSep simulation tool is being developed. ConSep is a generic MATLAB-based front-and-back-end to the commercially available ADAMS. solver, an industry standard package for solving multi-body dynamic problems. This paper discusses the 3-body separation capability in ConSep and its application to the separation of the Shuttle Solid Rocket Boosters (SRBs) from the External Tank (ET) and the Orbiter. The results are compared with STS-1 flight data

Simulation and Analyses of Stage Separation of Two-Stage Reusable Launch Vehicles

NASA has initiated the development of methodologies, techniques and tools needed for analysis and simulation of stage separation of next generation reusable launch vehicles. As a part of this activity, ConSep simulation tool is being developed which is a MATLAB-based front-and-back-end to the commercially available ADAMS(Registerd TradeMark) solver, an industry standard package for solving multi-body dynamic problems. This paper discusses the application of ConSep to the simulation and analysis of staging maneuvers of two-stage-to-orbit (TSTO) Bimese reusable launch vehicles, one staging at Mach 3 and the other at Mach 6. The proximity and isolated aerodynamic database were assembled using the data from wind tunnel tests conducted at NASA Langley Research Center. The effects of parametric variations in mass, inertia, flight path angle, altitude from their nominal values at staging were evaluated. Monte Carlo runs were performed for Mach 3 staging to evaluate the sensitivity to uncertainties in aerodynamic coefficients

Simulation and Analyses of Stage Separation Two-Stage Reusable Launch Vehicles

NASA has initiated the development of methodologies, techniques and tools needed for analysis and simulation of stage separation of next generation reusable launch vehicles. As a part of this activity, ConSep simulation tool is being developed which is a MATLAB-based front-and-back-end to the commercially available ADAMS(registered Trademark) solver, an industry standard package for solving multi-body dynamic problems. This paper discusses the application of ConSep to the simulation and analysis of staging maneuvers of two-stage-to-orbit (TSTO) Bimese reusable launch vehicles, one staging at Mach 3 and the other at Mach 6. The proximity and isolated aerodynamic database were assembled using the data from wind tunnel tests conducted at NASA Langley Research Center. The effects of parametric variations in mass, inertia, flight path angle, altitude from their nominal values at staging were evaluated. Monte Carlo runs were performed for Mach 3 staging to evaluate the sensitivity to uncertainties in aerodynamic coefficients

Application of the Life Safety Code to a Historic Test Stand

Presentation will: (1) Examine applicable life safety requirements and the context in which they were evaluated (2) Means by which occupant safety was ensure

Signal Processing Research Program

Contains table of contents for Part III, table of contents for Section 1, an introduction and reports on fourteen research projects.Charles S. Draper Laboratory Contract DL-H-404158U.S. Navy - Office of Naval Research Grant N00014-89-J-1489National Science Foundation Grant MIP 87-14969Battelle LaboratoriesTel-Aviv University, Department of Electronic SystemsU.S. Army Research Office Contract DAAL03-86-D-0001The Federative Republic of Brazil ScholarshipSanders Associates, Inc.Bell Northern Research, Ltd.Amoco Foundation FellowshipGeneral Electric FellowshipNational Science Foundation FellowshipU.S. Air Force - Office of Scientific Research FellowshipU.S. Navy - Office of Naval Research Grant N00014-85-K-0272Natural Science and Engineering Research Council of Canada - Science and Technology Scholarshi

Does the drug sensitivity of malaria parasites depend on their virulence?

<p>Abstract</p> <p>Background</p> <p>Chemotherapy can prompt the evolution of classical drug resistance, but selection can also favour other parasite traits that confer a survival advantage in the presence of drugs. The experiments reported here test the hypothesis that sub-optimal drug treatment of malaria parasites might generate survival and transmission advantages for virulent parasites.</p> <p>Methods</p> <p>Two <it>Plasmodium chabaudi </it>lines, one derived from the other by serial passage, were used to establish avirulent and virulent infections in mice. After five days, infections were treated with various doses of pyrimethamine administered over 1 or 4 days. Virulence measures (weight and anaemia), parasite and gametocyte dynamics were followed until day 21.</p> <p>Results</p> <p>All treatment regimes reduced parasite and gametocyte densities, but infections with the virulent line always produced more parasites and more gametocytes than infections with the avirulent line. Consistent with our hypothesis, drug treatment was disproportionately effective against the less virulent parasites. Treatment did not affect the relative transmission advantage of the virulent line. Neither of the lines contained known mutations conferring classical drug resistance.</p> <p>Conclusion</p> <p>Drug-sensitivity of malaria parasites can be virulence-dependent, with virulent parasites more likely to survive sub-optimal treatment. If this proves to be general for a variety of drugs and parasite species, selection imposed by sub-optimal drug treatment could result in the evolution of more aggressive malaria parasites.</p

The Deaf Community and Law Enforcement

[Chapter Abstract] Like any other population, the Deaf community as part of society will have individuals they come into contact with law enforcement officers and the criminal justice system. Because of differences in hearing ability and communication, law enforcement officers and both Deaf suspects and victims will often face challenges while navigating these interactions. The officer will not be likely to realize that a suspect or victim is Deaf until they are attempting to communicate. This can have dire consequences for the Deaf suspect who may find themselves at a disadvantage when interacting with law enforcement and may escalate routine situations. The Miranda warnings, interrogations, and criminal charges may also be affected by a lack of awareness and communication with Deaf suspects.https://nsuworks.nova.edu/cps_facbooks/1799/thumbnail.jp

Using Instructional Design, Analyze, Design, Develop, Implement, and Evaluate, to Develop e-Learning Modules to Disseminate Supported Employment for Community Behavioral Health Treatment Programs in New York State

BackgroundImplementation science lacks a systematic approach to the development of learning strategies for online training in evidence-based practices (EBPs) that takes the context of real-world practice into account. The field of instructional design offers ecologically valid and systematic processes to develop learning strategies for workforce development and performance support.ObjectiveThis report describes the application of an instructional design framework—Analyze, Design, Develop, Implement, and Evaluate (ADDIE) model—in the development and evaluation of e-learning modules as one strategy among a multifaceted approach to the implementation of individual placement and support (IPS), a model of supported employment for community behavioral health treatment programs, in New York State.MethodsWe applied quantitative and qualitative methods to develop and evaluate three IPS e-learning modules. Throughout the ADDIE process, we conducted formative and summative evaluations and identified determinants of implementation using the Consolidated Framework for Implementation Research (CFIR). Formative evaluations consisted of qualitative feedback received from recipients and providers during early pilot work. The summative evaluation consisted of levels 1 and 2 (reaction to the training, self-reported knowledge, and practice change) quantitative and qualitative data and was guided by the Kirkpatrick model for training evaluation.ResultsFormative evaluation with key stakeholders identified a range of learning needs that informed the development of a pilot training program in IPS. Feedback on this pilot training program informed the design document of three e-learning modules on IPS: Introduction to IPS, IPS Job development, and Using the IPS Employment Resource Book. Each module was developed iteratively and provided an assessment of learning needs that informed successive modules. All modules were disseminated and evaluated through a learning management system. Summative evaluation revealed that learners rated the modules positively, and self-report of knowledge acquisition was high (mean range: 4.4–4.6 out of 5). About half of learners indicated that they would change their practice after watching the modules (range: 48–51%). All learners who completed the level 1 evaluation demonstrated 80% or better mastery of knowledge on the level 2 evaluation embedded in each module. The CFIR was used to identify implementation barriers and facilitators among the evaluation data which facilitated planning for subsequent implementation support activities in the IPS initiative.ConclusionInstructional design approaches such as ADDIE may offer implementation scientists and practitioners a flexible and systematic approach for the development of e-learning modules as a single component or one strategy in a multifaceted approach for training in EBPs

Aerodynamic Characteristics and Glide-Back Performance of Langley Glide-Back Booster

NASA-Langley Research Center is conducting system level studies on an-house concept of a small launch vehicle to address NASA's needs for rapid deployment of small payloads to Low Earth Orbit. The vehicle concept is a three-stage system with a reusable first stage and expendable upper stages. The reusable first stage booster, which glides back to launch site after staging around Mach 3 is named the Langley Glide-Back Booster (LGBB). This paper discusses the aerodynamic characteristics of the LGBB from subsonic to supersonic speeds, development of the aerodynamic database and application of this database to evaluate the glide back performance of the LGBB. The aerodynamic database was assembled using a combination of wind tunnel test data and engineering level analysis. The glide back performance of the LGBB was evaluated using a trajectory optimization code and subject to constraints on angle of attack, dynamic pressure and normal acceleration