QUALIDADE DE VIDA EM PROFISSIONAIS DA SAÚDE: WHOQOL-bref

The objective of the study was to compare the characteristics of the sociodemographic, behavioral and Covid-19 variables with the domains and to associate the domains with the sociodemographic, behavioral and Covid-19 variables with the quality of life (QoL) in health professionals from five units basic health services (UBS) in Porto Velho/RO, 2021. Cross-sectional study with 85 health professionals. A questionnaire containing the WHOQOL-bref instrument and questions about sociodemographic characteristics was used. After descriptive analysis, simple and multiple linear regression was performed to assess the association between exposure variables and QoL domains. The worst QoL perceptions were associated with the physical and psychological domains of rental housing; the perception of health with physical, psychological, social relations and environment domains; physical activity at least twice a week physical, psychological and environmental; not leaving USF the physical and psychological; female sex social relationships (p<0.05). Efforts are needed to improve the QoL of professionals working at UBS, through actions promoted by public managers. These actions can bring benefits and reflect positively on the quality of life of these professionals by the actors involved in the Primary Health Care scenario.El objetivo de este estudio fue investigar la calidad de vida de los profesionales de salud de las unidades de salud de la familia en la ciudad de Porto Velho/RO. Estudio transversal no probabilístico por conveniencia, con una muestra de profesionales de cinco unidades, donde se envió tres cuestionarios y se obtuvo la devolución de 85 cuestionarios que cumplían con los criterios de inclusión. El análisis de datos se realizó con SPSS versión 20. Los principales hallazgos después de la correlación de variables y dominios fueron valores significativos en las variables percepción de salud y práctica de actividades físicas. Se concluye que la pandemia influyó en la salud de los profesionales, siendo la autopercepción negativa de la salud uno de los principales factores asociados a la baja calidad de vida de los servidores, seguido de la inactividad física. Realización de acciones de prevención y promoción necesarias para los servidores.O objetivo do estudo foi comparar as características das variáveis sociodemográfica, comportamentais e da Covid-19 com os domínios e associar os domínios com as variáveis sociodemográfica, comportamentais e da Covid-19 à qualidade de vida (QV) em profissionais da saúde de cinco unidades básicas de saúde (UBS) de Porto Velho/RO, 2021. Estudo de delineamento transversal com 85 profissionais de saúde. Utilizou-se um questionário contendo o instrumento WHOQOL-bref e perguntas sobre características sociodemográficas. Após análise descritiva, realizou-se regressão linear simples e múltipla para avaliar a associação entre as variáveis de exposição e os domínios da QV. As piores percepções de QV foram associadas aos domínios físicos e psicológicos à moradia de aluguel; a percepção de saúde com domínios físicos, psicológicos, relações social e meio ambiente; a atividade física menos duas vezes semanal o físico, psicológico e meio ambiente; não sair USF o físico e psicológico; sexo feminino as relações sociais (p<0,05). São necessários esforços para a melhoria da QV nos profissionais que atuam nas UBS, por meio de ações promovidas pelos gestores públicos. Essas ações podem trazer benefícios e refletir positivamente na qualidade de vida desses profissionais pelos atores envolvidos no cenário da Atenção Primária à Saúde

Subtractive libraries for prospecting differentially expressed genes in the soybean under water deficit

Soybean has a wide range of applications in the industry and, due to its crop potential, its improvement is widely desirable. During drought conditions, soybean crops suffer significant losses in productivity. Therefore, understanding the responses of the soybean under this stress is an effective way of targeting crop improvement techniques. In this study, we employed the Suppressive Subtractive Hybridization (SSH) technique to investigate differentially expressed genes under water deficit conditions. Embrapa 48 and BR 16 soybean lines, known as drought-tolerant and -sensitive, respectively, were grown hydroponically and subjected to different short-term periods of stress by withholding the nutrient solution. Using this approach, we have identified genes expressed during the early response to water deficit in roots and leaves. These genes were compared among the lines to assess probable differences in the plant transcriptomes. In general, similar biochemical processes were predominant in both cultivars; however, there were more considerable differences between roots and leaves of Embrapa 48. Moreover, we present here a fast, clean and straightforward method to obtain drought-stressed root tissues and a large enriched collection of transcripts expressed by soybean plants under water deficit that can be useful for further studies towards the understanding of plant responses to stress.304314Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq

Butyrate Protects Mice from Clostridium difficile-Induced Colitis through an HIF-1-Dependent Mechanism

Antibiotic-induced dysbiosis is a key factor predisposing intestinal infection by Clostridium difficile. Here, we show that interventions that restore butyrate intestinal levels mitigate clinical and pathological features of C. difficile-induced colitis. Butyrate has no effect on C. difficile colonization or toxin production. However, it attenuates intestinal inflammation and improves intestinal barrier function in infected mice, as shown by reduced intestinal epithelial permeability and bacterial translocation, effects associated with the increased expression of components of intestinal epithelial cell tight junctions. Activation of the transcription factor HIF-1 in intestinal epithelial cells exerts a protective effect in C. difficile-induced colitis, and it is required for butyrate effects. We conclude that butyrate protects intestinal epithelial cells from damage caused by C. difficile toxins via the stabilization of HIF-1, mitigating local inflammatory response and systemic consequences of the infection

Erosive pustular dermatosis of the scalp after aplasia cutis congenita in a 9-year-old patient: A 5-year follow-up

Erosive pustular dermatosis of the scalp (EPDS) is a rare inflammatory skin disease that occurs mainly in elderly adults with a history of trauma to the scalp, but a few cases of EPDS in children have been reported. We report a rare case of EPDS after aplasia cutis congenita in a child

Porta-enxerto e intensidade da poda de inverno para pessegueiro ‘Maciel’

Winter pruning has been a common practice in peach. Twig topping has been associated with it, but this practice has been used at the same intensity, regardless of the cultivar. Therefore, this study aimed at evaluating productive behavior and quality of ‘Maciel’ peach grafted on ‘Capdeboscq’ and ‘Okinawa’ (P. persica) as rootstocks, when they were submitted to different twig topping intensities in winter pruning. The following three pruning intensities were evaluated: short pruning, when 2/3 of the productive twig was removed; long pruning, when 1/3 of the twig was removed; and pruning with no topping, when twigs were kept integral. Effective fructification is lower when ‘Maciel’ peach trees are submitted to short pruning, but it leads to fruit with higher weight and flesh firmness, besides larger diameters. Pruning with no twig topping and long pruning increased the fruit number and yield per tree. Not only fruit weight, diameter and soluble solid content, but also yield per tree of ‘Maciel’ peach are affected by ‘Capdeboscq’ and ‘Okinawa’, regardless of the intensity of twig topping throughout pruning. Higher concentration of soluble solids was found in peaches grafted in Okinawa. While the highest production was verified with the use of the ‘Capdeboscq’ rootstock