A non-geodesic motion in the R^-1 theory of gravity tuned with observations

In the general picture of high order theories of gravity, recently, the R^-1 theory has been analyzed in two different frameworks. In this letter a third context is added, considering an explicit coupling between the R^-1 function of the Ricci scalar and the matter Lagrangian. The result is a non-geodesic motion of test particles which, in principle, could be connected with Dark Matter and Pioneer anomaly problems.Comment: Accepted for Modern Physics Letters

An application of multi-level DC-link converter for optimised permutation control of PV sources under partial shading

The paper describes application of a multi-level DC-link converter in overcoming the problem of partially shaded series-connected PV sources. The converter control engages a permutation algorithm which enables each PV source of the string to produce the maximum power. The main features of the system are: (i) a continual operation of all PV sources, shaded and non-shaded, at their maximum power points, (ii) delivery of all extracted power from PV sources to the load and (ii) generation of multi-level output voltage waveform with a low total harmonic distortion

Behavior of Some Earth Dams on Liquefiable Soil

The 1977 March 4 Vrancea earthquake emphasized several zones with liquefiable materials on Romanian territory. Some earth dams of such zones, placed to over 200 km from the earthquake epicenter were damaged. Important hydropower works are at present in different design or construction stages in such area, comprising long earth dams. The Seismic analysis procedure applied to their design was based on the finite element method. Some characteristic cross - sections of the earth dams in different versions have been studied. The analysed sections had different shapes (with and without stabilizing benches downstream) and included different zoning of the materials (sand fine sand and free draining materials). The analyses pointed out the importance of the drainage blanket at the base of the dam for the increase of the liquefaction strength capacity of the soil - structure system. Some improvement works in certain zones of the foundation soil resulted as being necessary

Alternative livelihoods in a coastal village

Women, Gender, Economic situation, Philippines,

Interferometer Response to Scalar Gravitational Waves

It was recently suggested that the magnetic component of Gravitational Waves (GWs) is relevant in the evaluation of frequency response functions of gravitational interferometers. In this paper we extend the analysis to the magnetic component of the scalar mode of GWs which arise from scalar-tensor gravity theory. In the low-frequency approximation, the response function of ground-based interferometers is calculated. The angular dependence of the electric and magnetic contributions to the response function is discussed. Finally, for an arbitrary frequency range, the proper distance between two test masses is calculated and its usefulness in the high-frequency limit for space-based interferometers is briefly considered.Comment: Accepted for publication by Int. Journ. Mod. Phys. D. Final versio

key findings

publishersversionpublishe

The burden of cardiovascular disease associated with PM2.5 exposure in the Portuguese population

publishersversionpublishe

A precise response function for the magnetic component of Gravitational Waves in Scalar-Tensor Gravity

The important issue of the magnetic component of gravitational waves (GWs) has been considered in various papers in the literature. From such analyses, it resulted that such a magnetic component becomes particularly important in the high frequency portion of the frequency range of ground based interferometers for GWs which arises from standard General Theory of Relativity (GTR). Recently, such a magnetic component has been extended to GWs arising from Scalar-Tensor Gravity (STG) too. After a review of some important issues on GWs in STG, in this paper we re-analyse the magnetic component in the framework of STG from a different point of view, by correcting an error in a previous paper and by releasing a more precise response function. In this way, we also show that if one neglects the magnetic contribution considering only the low-frequency approximation of the electric contribution, an important part of the signal could be, in principle, lost. The determination of a more precise response function for the magnetic contribution is important also in the framework of the possibility to distinguish other gravitational theories from GTR. At the end of the paper an expansion of the main results is also shown in order to recall the presence of the magnetic component in GRT too.Comment: Accepted for publication in Physical Review D, to be published during 2011. 36 pages, in this second version typos have been corrected and references have been update

Three new Alpha1-Antitrypsin deficiency variants help to define a C-Terminal region regulating conformational change and polymerization

Alpha1-antitrypsin (AAT) deficiency is a hereditary disorder associated with reduced AAT plasma levels, predisposing adults to pulmonary emphysema. The most common genetic AAT variants found in patients are the mildly deficient S and the severely deficient Z alleles, but several other pathogenic rare alleles have been reported. While the plasma AAT deficiency is a common trait of the disease, only a few AAT variants, including the prototypic Z AAT and some rare variants, form cytotoxic polymers in the endoplasmic reticulum of hepatocytes and predispose to liver disease. Here we report the identification of three new rare AAT variants associated to reduced plasma levels and characterize their molecular behaviour in cellular models. The variants, called Mpisa (Lys259Ile), Etaurisano (Lys368Glu) and Yorzinuovi (Pro391His), showed reduced secretion compared to control M AAT, and accumulated to different extents in the cells as ordered polymeric structures resembling those formed by the Z variant. Structural analysis of the mutations showed that they may facilitate polymerization both by loosening ‘latch’ interactions constraining the AAT reactive loop and through effects on core packing. In conclusion, the new AAT deficiency variants, besides increasing the risk of lung disease, may predispose to liver disease, particularly if associated with the common Z variant. The new mutations cluster structurally, thus defining a region of the AAT molecule critical for regulating its conformational state