À corps ouverts. Changement et échange d’identités dans la Capoeira et le contact improvisation

Cet article tente de montrer comment deux formes particulières de la danse contemporaine, la Capoeira et le contact improvisation peuvent fournir des modèles – et même des technologies physiques – à partir desquels théoriser une altérité incarnée. Il montre comment ces formes de danse proviennent de cultures et d’histoires spécifiques mais aussi comment, dans leurs manifestations contemporaines, elles possèdent leur propre logique qui nous force à repenser notre compréhension des corps et des cultures.This paper addresses how two different contemporary dance forms – Capoeira and Contact Improvisation – can provide models (even physical technologies) with which to theorize an embodied « altérité » or otherness. I will demonstrate how these forms came from specific cultural and historical locations, as well as how, in their contemporary manifestations, they embody their own inner logic, asking us to rethink our understanding of bodies and cultures

The Tensions of Technē: On Heidegger and Screendance

No abstract availableThis article was originally published by Parallel Press, an imprint of the University of Wisconsin-Madison Libraries, as part of The International Journal of Screendance, Volume 2 (2012), Parallel Press. It is made available here with the kind permission of Parallel Press

MOVENDO-SE ATRAVÉS DA DIFERENÇA: DANÇA E DEFICIÊNCIA

This article focuses on the notion of disability, questioning the ways in which professional dance has traditionally been structured by an exclusionary mindset that projects a vision of a dancer as white, female, thin, long-limbed, flexible and able-bodied. It also addresses the growing desire to radically revise this paradigm reenvisioning what kinds of movements can constitute a dance and, by extension, what kind of body can constitute a dancer. Although most of the discussion is centered in specific dances and in several critical responses to them, it is also proposed to reveal the complex ways in which the opposition of fit and frail bodies is implicated within many of the dominant cultural paradigms of health and self-determination.O artigo centra-se na noção de deficiência, questionando as maneiras como a dança profissional tem sido tradicionalmente estruturada por uma mentalidade exclusivista que projeta uma visão de um  bailarino como sendo branco, do sexo feminino, esbelto, de membros alongados, flexível e capaz (não deficiente). Aborda igualmente o crescente desejo de revisar radicalmente este paradigma reimaginando que tipos de movimentos podem constituir a dança e, por extensão, que tipo de corpo pode constituir um bailarino. Apesar da maior parte das discussões centralizar-se em danças específicas e nas várias respostas críticas a elas, propõe-se também a revelar as maneiras complexas pelas quais a oposição de corpos plenamente capazes e de corpos debilitados estão implicados em muitos dos paradigmas culturais dominantes de saúde e autodeterminação

High quality and quantity Genome-wide germline genotypes from FFPE normal tissue

<p>Abstract</p> <p>Background</p> <p>Although collections of formalin fixed paraffin embedded (FFPE) samples exist, sometimes representing decades of stored samples, they have not typically been utilized to their full potential. Normal tissue from such samples would be extremely valuable for generation of genotype data for individuals who cannot otherwise provide a DNA sample.</p> <p>Findings</p> <p>We extracted DNA from normal tissue identified in FFPE tissue blocks from prostate surgery and obtained complete genome wide genotype data for over 500,000 SNP markers for these samples, and for DNA extracted from whole blood for 2 of the cases, for comparison.</p> <p>Four of the five FFPE samples of varying age and amount of tissue had identifiable normal tissue. We obtained good quality genotype data for between 89 and 99% of all SNP markers for the 4 samples from FFPE. Concordance rates of over 99% were observed for the 2 samples with DNA from both FFPE and from whole blood.</p> <p>Conclusions</p> <p>DNA extracted from normal FFPE tissue provides excellent quality and quantity genome-wide genotyping data representing germline DNA, sufficient for both linkage and association analyses. This allows genetic analysis of informative individuals who are no longer available for sampling in genetic studies.</p

Multiple novel prostate cancer susceptibility signals identified by fine-mapping of known risk loci among Europeans

Genome-wide association studies (GWAS) have identified numerous common prostate cancer (PrCa) susceptibility loci. We have fine-mapped 64 GWAS regions known at the conclusion of the iCOGS study using large-scale genotyping and imputation in 25 723 PrCa cases and 26 274 controls of European ancestry. We detected evidence for multiple independent signals at 16 regions, 12 of which contained additional newly identified significant associations. A single signal comprising a spectrum of correlated variation was observed at 39 regions; 35 of which are now described by a novel more significantly associated lead SNP, while the originally reported variant remained as the lead SNP only in 4 regions. We also confirmed two association signals in Europeans that had been previously reported only in East-Asian GWAS. Based on statistical evidence and linkage disequilibrium (LD) structure, we have curated and narrowed down the list of the most likely candidate causal variants for each region. Functional annotation using data from ENCODE filtered for PrCa cell lines and eQTL analysis demonstrated significant enrichment for overlap with bio-features within this set. By incorporating the novel risk variants identified here alongside the refined data for existing association signals, we estimate that these loci now explain ∼38.9% of the familial relative risk of PrCa, an 8.9% improvement over the previously reported GWAS tag SNPs. This suggests that a significant fraction of the heritability of PrCa may have been hidden during the discovery phase of GWAS, in particular due to the presence of multiple independent signals within the same regio