155 research outputs found
Geometry acquisition and grid generation: Recent experiences with complex aircraft configurations
Important issues involved in working with complex geometries are discussed. Approaches taken to address complex geometry issues in the McDonnell Aircraft Computational Grid System and related geometry processing tools are discussed. The efficiency of acquiring a suitable geometry definition, the need to manipulate the geometry, and the time and skill level required to generate the grid while preserving geometric fidelity are discussed
Dediščina izjemnih osebnosti kot potencial za razvoj kulturnega turizma v Romuniji
This article investigates how domestic tourists perceive the possibilities of boosting cultural heritage tourism in Romania, through the capitalization of national genius personalities. The methodology is based on the survey method. The research identified 22 geniuses, largely represented in national culture, and acknowledged and demanded by the market. The vast majority have been converted into tourist attractions, however those of international visibility are missing or are underrepresented in Romanian heritage tourism. An increased focus on geniuses would be highly valued by tourists and could reinforce the value of cultural heritage, consequently, boosting tourism resources. This would lead to multiple and sustainable benefits for destinations’ development, but certain infrastructure and management gaps would need to be filled.Avtorji v članku proučujejo mnenja domačih turistov o možnostih spodbujanja razvoja kulturnega turizma v Romuniji na podlagi izjemnih osebnosti iz romunske kulturne zgodovine. Uporabljena metodologija temelji na anketi, v kateri so vprašani izpostavili 22 romunskih kulturnih osebnosti, prepoznanih na trgu. Večina je bila preobražena v turistične zanimivosti, pri čemer pa v romunskem dediščinskem turizmu manjkajo mednarodno prepoznavne osebnosti ali so te slabo zastopane. Večji poudarek na tovrstnih osebnostih bi turisti zelo dobro sprejeli, hkrati bi se s tem povečala vrednost kulturne dediščine, kar bi posledično spodbudilo razvoj novih turističnih virov. Navedeno bi imelo različne trajnostne koristi za razvoj destinacij, treba pa bi bilo zapolniti nekatere vrzeli v infrastrukturi in upravljanju
Expressions 2019
https://openspace.dmacc.edu/expressions/1035/thumbnail.jp
A mathematical model for top-shelf vertigo: the role of sedimenting otoconia in BPPV
Benign Paroxysmal Positional Vertigo (BPPV) is a mechanical disorder of the
vestibular system in which calcite particles called otoconia interfere with the
mechanical functioning of the fluid-filled semicircular canals normally used to
sense rotation. Using hydrodynamic models, we examine the two mechanisms
proposed by the medical community for BPPV: cupulolithiasis, in which otoconia
attach directly to the cupula (a sensory membrane), and canalithiasis, in which
otoconia settle through the canals and exert a fluid pressure across the
cupula. We utilize known hydrodynamic calculations and make reasonable
geometric and physical approximations to derive an expression for the
transcupular pressure exerted by a settling solid particle in
canalithiasis. By tracking settling otoconia in a two-dimensional model
geometry, the cupular volume displacement and associated eye response
(nystagmus) can be calculated quantitatively. Several important features
emerge: 1) A pressure amplification occurs as otoconia enter a narrowing duct;
2) An average-sized otoconium requires approximately five seconds to settle
through the wide ampulla, where is not amplified, which suggests a
mechanism for the observed latency of BPPV; and 3) An average-sized otoconium
beginning below the center of the cupula can cause a volumetric cupular
displacement on the order of 30 pL, with nystagmus of order /s, which
is approximately the threshold for sensation. Larger cupular volume
displacement and nystagmus could result from larger and/or multiple otoconia.Comment: 15 pages, 5 Figures updated, to be published in J. Biomechanic
Therapeutic Use of Bacteriophage and Antibiotic Formulations for the Treatment of Antibiotic Resistant Acinetobacter Baumannii
Gemstone Team LYTICWidespread use of antibiotics has enriched global bacteria populations for strains
possessing antibiotic resistance (AR) genes. Proliferation of AR genes and mechanisms
have resulted in numerous multidrug resistant (MDR) infections for which there are no
effective treatments. Acinetobacter baumannii is a major cause of hospital acquired
(nosocomial) infections and is associated with outbreaks of MDR infections. Virulent
bacteriophages (phages) present a way to remedy bacterial infections, while also having
built-in mechanisms to circumvent resistance. This proposed study aims to develop a
phage therapeutic targeting antibiotic resistant A. baumannii. The phages chosen for the
final formulation exhibited high bactericidal activity and were able to infect several
strains of A. baumannii from a provided library. Additionally, the phage-antibiotic
synergy (PAS) effect was investigated in formulations with sub-lethal doses of ampicillin
and chloramphenicol. The effectiveness of the phage therapeutic at different multiplicity
of infections (MOI) and antibiotic concentrations were assessed relative to standard antibiotic doses. Well-plate studies suggest that higher MOI and antibiotic concentrations
resulted in the greatest initial bactericidal effects, longest time to develop resistance, and
lowest overall bacteria concentration. In future formulation studies, we would like to
expand and optimize the current phage-antibiotic formulation and explore cocktail
effects, whereby the formulation consists of a mixture of different phages that increases
selective pressure
Information Display System for Atypical Flight Phase
Method and system for displaying information on one or more aircraft flights, where at least one flight is determined to have at least one atypical flight phase according to specified criteria. A flight parameter trace for an atypical phase is displayed and compared graphically with a group of traces, for the corresponding flight phase and corresponding flight parameter, for flights that do not manifest atypicality in that phase
Evaporated manganese films as a starting point for the preparation of thin-layer MnO x water-oxidation anodes
A novel method to prepare anodes for water electrolysis cells has been developed, which starts from layers of elemental manganese deposited by physical vapour deposition (PVD) on indium-doped tin oxide (ITO). Oxidation in dry air at 300 °C transforms this metallic Mn layer into a manganese(II)-rich MnOx coating (x = 1–1.3), which also contains a buried layer of an In–Sn alloy originating from reactions with the ITO support. The MnOx films are well connected to the underlying substrate and act as efficient catalysts for water-oxidation catalysis (WOC) at neutral pH. Detailed post-operando analyses using XRD, SEM, TEM and XAS revealed that the dense MnO/Mn3O4 film is virtually not affected by 2 h of electrochemical WOC at E ≈ +1.8 V vs. RHE, corresponding well to the observed good stability of catalytic currents, which is unusual for such thin layers of a MnOx catalyst. The current densities during electrolyses are so far low (i ≈ 50–100 μA cm−2 at pH 7), but optimization of the preparation process may allow for significant improvements. This new, rather easy, and adaptable preparation method for stable, thin-layer MnOx water-oxidation anodes could thus prove to be very useful for a variety of applications
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