Modelling of Atherosclerotic Plaque for Use in a Computational Test-Bed for Stent Angioplasty

A thorough understanding of the diseased tissue state is necessary for the successful treatment of a blocked arterial vessel using stent angioplasty. The constitutive representation of atherosclerotic tissue is of great interest to researchers and engineers using computational models to analyse stents, as it is this in silico environment that allows extensive exploration of tissue response to device implantation. This paper presents an in silico evaluation of the effects of variation of atherosclerotic tissue constitutive representation on tissue mechanical response during stent implantation. The motivation behind this work is to investigate the level of detail that is required when modelling atherosclerotic tissue in a stenting simulation, and to give recommendations to the FDA for their guideline document on coronary stent evaluation, and specifically the current requirements for computational stress analyses. This paper explores the effects of variation of the material model for the atherosclerotic tissue matrix, the effects of inclusion of calcifications and a lipid pool, and finally the effects of inclusion of the Mullins effect in the atherosclerotic tissue matrix, on tissue response in stenting simulations. Results indicate that the inclusion of the Mullins effect in a direct stenting simulation does not have a significant effect on the deformed shape of the tissue or the stress state of the tissue. The inclusion of a lipid pool induces a local redistribution of lesion deformation for a soft surrounding matrix and the inclusion of a small volume of calcifications dramatically alters the local results for a soft surrounding matrix. One of the key findings from this work is that the underlying constitutive model (elasticity model) used for the atherosclerotic tissue is the dominant feature of the tissue representation in predicting tissue response in a stenting simulation

How to obtain a lattice basis from a discrete projected space

International audienceEuclidean spaces of dimension n are characterized in discrete spaces by the choice of lattices. The goal of this paper is to provide a simple algorithm finding a lattice onto subspaces of lower dimensions onto which these discrete spaces are projected. This first obtained by depicting a tile in a space of dimension n -- 1 when starting from an hypercubic grid in dimension n. Iterating this process across dimensions gives the final result

On the deflection of asteroids with mirrors

This paper presents an analysis of an asteroid deflection method based on multiple solar concentrators. A model of the deflection through the sublimation of the surface material of an asteroid is presented, with simulation results showing the achievable orbital deflection with, and without, accounting for the effects of mirror contamination due to the ejected debris plume. A second model with simulation results is presented analyzing an enhancement of the Yarkovsky effect, which provides a significant deflection even when the surface temperature is not high enough to sublimate. Finally the dynamical model of solar concentrators in the proximity of an irregular celestial body are discussed, together with a Lyapunov-based controller to maintain the spacecraft concentrators at a required distance from the asteroid

Supersymmetric Heterotic Action out of M5 Brane

Generalizing the work by Cherkis and Schwarz [1], we carry out the double dimensional reduction of supersymmetric M5 brane on K3 to obtain the supersymmetric action of heterotic string in 7-dimensional flat space-time. Motivated by this result, we propose the supersymmetric heterotic action in 10-dimensional flat space-time where the current algebra is realized in a novel way. We explicitly verify the kappa-symmetry of the proposed action.Comment: 27 page

Effects of azimuth-symmetric acceptance cutoffs on the measured asymmetry in unpolarized Drell-Yan fixed target experiments

Fixed-target unpolarized Drell-Yan experiments often feature an acceptance depending on the polar angle of the lepton tracks in the laboratory frame. Typically leptons are detected in a defined angular range, with a dead zone in the forward region. If the cutoffs imposed by the angular acceptance are independent of the azimuth, at first sight they do not appear dangerous for a measurement of the cos(2\phi)-asymmetry, relevant because of its association with the violation of the Lam-Tung rule and with the Boer-Mulders function. On the contrary, direct simulations show that up to 10 percent asymmetries are produced by these cutoffs. These artificial asymmetries present qualitative features that allow them to mimic the physical ones. They introduce some model-dependence in the measurements of the cos(2\phi)-asymmetry, since a precise reconstruction of the acceptance in the Collins-Soper frame requires a Monte Carlo simulation, that in turn requires some detailed physical input to generate event distributions. Although experiments in the eighties seem to have been aware of this problem, the possibility of using the Boer-Mulders function as an input parameter in the extraction of Transversity has much increased the requirements of precision on this measurement. Our simulations show that the safest approach to these measurements is a strong cutoff on the Collins-Soper polar angle. This reduces statistics, but does not necessarily decrease the precision in a measurement of the Boer-Mulders function.Comment: 13 pages, 14 figure

Компонентный состав фразеологических единиц, мотивирующих слова (на материале немецкого языка)

Статья из специализированного выпуска научного журнала "Культура народов Причерноморья", материалы которого объединены общей темой "Язык и Мир" и посвящены общим вопросам Языкознания и приурочены к 80-летию со дня рождения Николая Александровича Рудякова.Стаття із спеціалізованого випуску наукового журналу "Культура народов Причерноморья", матеріали якого поєднані загальною темою "Мова і Світ" і присвячені загальним питанням мовознавства і приурочені до 80-річчя з дня народження Миколи Олександровича Рудякова

A framework for the local information dynamics of distributed computation in complex systems

The nature of distributed computation has often been described in terms of the component operations of universal computation: information storage, transfer and modification. We review the first complete framework that quantifies each of these individual information dynamics on a local scale within a system, and describes the manner in which they interact to create non-trivial computation where "the whole is greater than the sum of the parts". We describe the application of the framework to cellular automata, a simple yet powerful model of distributed computation. This is an important application, because the framework is the first to provide quantitative evidence for several important conjectures about distributed computation in cellular automata: that blinkers embody information storage, particles are information transfer agents, and particle collisions are information modification events. The framework is also shown to contrast the computations conducted by several well-known cellular automata, highlighting the importance of information coherence in complex computation. The results reviewed here provide important quantitative insights into the fundamental nature of distributed computation and the dynamics of complex systems, as well as impetus for the framework to be applied to the analysis and design of other systems.Comment: 44 pages, 8 figure

Initial-State Interactions in the Unpolarized Drell-Yan Process

We show that initial-state interactions contribute to the $\cos 2 \phi$ distribution in unpolarized Drell-Yan lepton pair production $p p$ and $p \bar p \to \ell^+ \ell^- X$, without suppression. The asymmetry is expressed as a product of chiral-odd distributions $h_1^\perp(x_1,\bm{p}_\perp^2)\times \bar h_1^\perp(x_2,\bm{k}_\perp^2)$, where the quark-transversity function $h_1^\perp(x,\bm{p}_\perp^2)$ is the transverse momentum dependent, light-cone momentum distribution of transversely polarized quarks in an {\it unpolarized} proton. We compute this (naive) $T$-odd and chiral-odd distribution function and the resulting $\cos 2 \phi$ asymmetry explicitly in a quark-scalar diquark model for the proton with initial-state gluon interaction. In this model the function $h_1^\perp(x,\bm{p}_\perp^2)$ equals the $T$-odd (chiral-even) Sivers effect function $f^\perp_{1T}(x,\bm{p}_\perp^2)$. This suggests that the single-spin asymmetries in the SIDIS and the Drell-Yan process are closely related to the $\cos 2 \phi$ asymmetry of the unpolarized Drell-Yan process, since all can arise from the same underlying mechanism. This provides new insight regarding the role of quark and gluon orbital angular momentum as well as that of initial- and final-state gluon exchange interactions in hard QCD processes.Comment: 22 pages, 6 figure

Supermassive Binaries and Extragalactic Jets

Some quasars show Doppler shifted broad emission line peaks. I give new statistics of the occurrence of these peaks and show that, while the most spectacular cases are in quasars with strong radio jets inclined to the line of sight, they are also almost as common in radio-quiet quasars. Theories of the origin of the peaks are reviewed and it is argued that the displaced peaks are most likely produced by the supermassive binary model. The separations of the peaks in the 3C 390.3-type objects are consistent with orientation-dependent "unified models" of quasar activity. If the supermassive binary model is correct, all members of "the jet set" (astrophysical objects showing jets) could be binaries.Comment: 31 pages, PostScript, missing figure is in ApJ 464, L105 (see http://www.aas.org/ApJ/v464n2/5736/5736.html