Topología lineal a pedazos, transformaciones periódicas en esferas homológicas y el invariante de Rohlin

Tesis Univ. Compl. Dpto. de Geometría y Topología. Dir. por Jose María Montesinos, leída en Madrid el17 de diciembre de 1979.Depto. de Álgebra, Geometría y TopologíaFac. de Ciencias MatemáticasTRUEProQuestpu

Recommendations for diagnosis, treatment and prevention of community-acquired pneumonia in immunocompetent adults

Introducción En nombre de las Asociaciones Colombianas de Neumología y Cirugía del Tórax, de Medicina Crítica y Cuidado Intensivo, de Medicina Interna y de Infectología, es un placer presentar las “Recomendaciones para el diagnóstico, tratamiento y prevención de la neumonía adquirida en la comunidad en adultos inmunocompetentes”. Este el fruto de un trabajo en conjunto durante tres años, en los cuales profesionales de las 4 asociaciones contribuyeron en el desarrollo de este documento que actualiza la versión previa de la guía del 2003. En este documento, no solo se tuvo en cuenta la mejor evidencia disponible publicada mediante la evaluación de guías existentes y búsquedas primarias, sino que también se incluyó información valiosa publicada localmente, especialmente datos epidemiológicos relacionados con etiología y resistencia bacteriana, entre otros.Guía de práctica clínica1-3

Itinerarios políticos contemporáneos en Argentina, Brasil, Chile y Uruguay

Este libro recoge la producción realizada en el marco del Proyecto de Investigación “Itinerarios de las democracias en Argentina, Brasil, Chile y Uruguay en el siglo XXI”, dirigido por Cintia Pinillos y codirigido por Juan Bautista Lucca. El mismo está radicado en la Facultad de Ciencia Política y Relaciones Internacionales de la Universidad Nacional de Rosario (Argentina) y está integrado por docentes-investigadores/as y por estudiantes de grado y posgradoFil: Cavarozzi, Marcelo. Universidad Nacional de San Martín. Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET); Argentina.Fil: Pinillos, Cintia. Universidad Nacional de Rosario. Facultad de Ciencia Política y Relaciones Internacionales; Argentina.Fil: Sartor Schiavoni, María Laura. Universidad Nacional de Rosario, Argentina.Fil: Caballero Rossi, Elisa. Universidad Nacional de Rosario; Argentina.Fil: Castagno, Aldana. Universidad Nacional de Rosario; Argentina.Fil: Prado, Amalia. Universidad Nacional de Rosario; Argentina.Fil: Pierotti, María Antonela. Universidad Nacional de Rosario. Facultad de Ciencia Política y Relaciones Internacionales; Argentina.Fil: Lucca, Juan Bautista. Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET). Universidad Nacional de Rosario; Argentina.Fil: Lodi, María Lourdes. Universidad Nacional de Rosario. Facultad de Ciencia Política y Relaciones Internacionales; Argentina.Fil: Vinuesa, Lucía. Universidad Nacional de Rosario. Facultad de Ciencia Política y Relaciones Internacionales; Argentina.Fil: Motter, Maite Cecilia. Universidad Nacional de Rosario; Argentina.Fil: Benetti, Gabriela.Universidad Nacional de Rosario; Argentina.Fil: Iglesias, Esteban. Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET). Universidad Nacional de Rosario; Argentina.Fil: Osorio, Rodrigo. Universidad de Santiago de Chile; Chile.Fil: Mella Polanco, Marcelo. Universidad Nacional de Santiago de Chile; Chile.Fil: Pérez Contreras, Aníbal. Universidad de Santiago de Chile; Chile

Carta de Psicología No. 53

Comprensión neuropsicológica de la enfermedad de Parkinson........3 María Fernanda Obregón Guavita Aprendizajes y experiencias en el semillero LAPSUCC: nuestro año como investigadores en neuropsicología ......6 Gabriel Almeida, María Paula Bernal, Laura Valentina Ruiz, Daniela Arévalo y Tatiana Manrique Entrenamiento cognitivo en el deterioro cognitivo leve - Trastorno neurocognitivo leve. 9 Luz Adriana Penagos, Angie Tatiana Contreras Cifuentes, Jhon Erick Chacón Ruiz, María Emily Triana, Daniela Alejandra Martínez Sarmiento, Valeria Valentina Palencia Amaya, Juliana Martínez Cárdenas, Natalia Caicedo Tamara, Johanna Castillo, María Lucía Blanco Parga, Ana Lorena Muñoz Valdés, Miguel Ángel Patarroyo, Sonia Gisela Ríos Cruz Articulación: de la educación media a superior...16 Daniela García, Camila Clavijo, Paola Peñuela, Tatiana Flores Mediación de la trascendencia en el ámbito educativo....18 Estefany Cuéllar González, Laura Camila Vargas López, Importancia de la orientación temporal en el niño........20 Andrómeda Katherine Gutiérrez Rueda, Claudia Paola Martínez Devia La castración química: el debate del populismo punitivo....22 Daniel Ricardo Riaño García, Laura Camila Jaimes Castillo, Angie Nathaly Infante , Hernández, Ever José López Cantero, Factores psicológicos en las personas privadas de la libertad condenadas por el delito de violencia intrafamiliar......26 Gerardo Andrés Merchán Mesa, Jordan Micaela Castelblanco Zamora, Ever José López Cantero, Karol Tatiana Triana Caballero, Katherine Álvarez Modelo ecológico para la compresión de las conductas infractoras en adolescentes.....29 Ana María Altamar Escorcia, Daniela Alvarado Ospina, María Isabel Castillo Camargo, Adriana Yulieth, Gómez Núñez, Ever José López Cantero, Luz Ángela Vega Gómez, Rocío Ordóñez Gómez, Bertha Liliana Ortiz Triviño y Lorena Osorio Rosales Inteligencia emocional y estrés académico en estudiantes universitarios.... 35 Johana Orozco, Valery Ramírez, María José Saavedra, y Javier Yépez Arrieta Uso de minería de textos para la exploración de creencias epistemológicas....37 Santiago Amaya Nassar Emociones, dinero, amigos y sexualidad en universitarios durante la cuarentena..... 42 Daniela Barbosa Sentido de comunidad: hacia una nueva conciencia comunitaria.....................45 Xiomara González Alarcón Participación y sentido de país.........47 Angie Lorena Ruiz, Andrea Lorena Villamil El semillero, una oportunidad de formación para estudiantes de pregrado y de especialización...........50 Liliana Quintero e Itala Marina Camargo Uso de minería de textos para el análisis de la participación de los egresados en los órganos de gobierno de las instituciones de educación superior .52 Sergio Andrés Flautero Mes

La función de la Corte Penal Internacional: visiones plurales desde una perspectiva interdisciplinar

El presente libro hace parte de los trabajos del grupo de justicia nacional de la “Red de Investigación Perspectivas Iberoamericanas sobre la Justicia”, coordinada desde el Instituto Ibero-Americano de la Haya para la Paz, los Derechos Humanos y la Justicia Internacional (IIH) (Países Bajos). Así mismo, se inscribe dentro de los proyectos de investigación: (a) “La función de la Corte Penal Internacional desde las teorías de la justicia en el derecho internacional” (2019-2020), cofinanciado por la Facultad de Jurisprudencia de la Universidad del Rosario (Bogotá, Colombia) y el IIH (Países Bajos); y (b) “La respuesta del derecho internacional a la corrupción asociada al crimen transnacional organizado” (2019-2021), con número de referencia VFPC009, cofinanciado por la Dirección de Investigación e Innovación y la Facultad de Jurisprudencia de la Universidad del Rosario (Bogotá, Colombia), así como por el IIH (Países Bajos). Ambos proyectos se encuentran adscritos a la línea de investigación “Crítica al derecho internacional desde fundamentos filosóficos”, del Grupo de Investigación en DI de la Facultad de Jurisprudencia de la Universidad del Rosario

Contemporary use of cefazolin for MSSA infective endocarditis: analysis of a national prospective cohort

Objectives: This study aimed to assess the real use of cefazolin for methicillin-susceptible Staphylococcus aureus (MSSA) infective endocarditis (IE) in the Spanish National Endocarditis Database (GAMES) and to compare it with antistaphylococcal penicillin (ASP). Methods: Prospective cohort study with retrospective analysis of a cohort of MSSA IE treated with cloxacillin and/or cefazolin. Outcomes assessed were relapse; intra-hospital, overall, and endocarditis-related mortality; and adverse events. Risk of renal toxicity with each treatment was evaluated separately. Results: We included 631 IE episodes caused by MSSA treated with cloxacillin and/or cefazolin. Antibiotic treatment was cloxacillin, cefazolin, or both in 537 (85%), 57 (9%), and 37 (6%) episodes, respectively. Patients treated with cefazolin had significantly higher rates of comorbidities (median Charlson Index 7, P <0.01) and previous renal failure (57.9%, P <0.01). Patients treated with cloxacillin presented higher rates of septic shock (25%, P = 0.033) and new-onset or worsening renal failure (47.3%, P = 0.024) with significantly higher rates of in-hospital mortality (38.5%, P = 0.017). One-year IE-related mortality and rate of relapses were similar between treatment groups. None of the treatments were identified as risk or protective factors. Conclusion: Our results suggest that cefazolin is a valuable option for the treatment of MSSA IE, without differences in 1-year mortality or relapses compared with cloxacillin, and might be considered equally effective

Global variation in postoperative mortality and complications after cancer surgery: a multicentre, prospective cohort study in 82 countries

© 2021 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY-NC-ND 4.0 licenseBackground: 80% of individuals with cancer will require a surgical procedure, yet little comparative data exist on early outcomes in low-income and middle-income countries (LMICs). We compared postoperative outcomes in breast, colorectal, and gastric cancer surgery in hospitals worldwide, focusing on the effect of disease stage and complications on postoperative mortality. Methods: This was a multicentre, international prospective cohort study of consecutive adult patients undergoing surgery for primary breast, colorectal, or gastric cancer requiring a skin incision done under general or neuraxial anaesthesia. The primary outcome was death or major complication within 30 days of surgery. Multilevel logistic regression determined relationships within three-level nested models of patients within hospitals and countries. Hospital-level infrastructure effects were explored with three-way mediation analyses. This study was registered with ClinicalTrials.gov, NCT03471494. Findings: Between April 1, 2018, and Jan 31, 2019, we enrolled 15 958 patients from 428 hospitals in 82 countries (high income 9106 patients, 31 countries; upper-middle income 2721 patients, 23 countries; or lower-middle income 4131 patients, 28 countries). Patients in LMICs presented with more advanced disease compared with patients in high-income countries. 30-day mortality was higher for gastric cancer in low-income or lower-middle-income countries (adjusted odds ratio 3·72, 95% CI 1·70–8·16) and for colorectal cancer in low-income or lower-middle-income countries (4·59, 2·39–8·80) and upper-middle-income countries (2·06, 1·11–3·83). No difference in 30-day mortality was seen in breast cancer. The proportion of patients who died after a major complication was greatest in low-income or lower-middle-income countries (6·15, 3·26–11·59) and upper-middle-income countries (3·89, 2·08–7·29). Postoperative death after complications was partly explained by patient factors (60%) and partly by hospital or country (40%). The absence of consistently available postoperative care facilities was associated with seven to 10 more deaths per 100 major complications in LMICs. Cancer stage alone explained little of the early variation in mortality or postoperative complications. Interpretation: Higher levels of mortality after cancer surgery in LMICs was not fully explained by later presentation of disease. The capacity to rescue patients from surgical complications is a tangible opportunity for meaningful intervention. Early death after cancer surgery might be reduced by policies focusing on strengthening perioperative care systems to detect and intervene in common complications. Funding: National Institute for Health Research Global Health Research Unit

Effects of hospital facilities on patient outcomes after cancer surgery: an international, prospective, observational study

© 2022 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 licenseBackground: Early death after cancer surgery is higher in low-income and middle-income countries (LMICs) compared with in high-income countries, yet the impact of facility characteristics on early postoperative outcomes is unknown. The aim of this study was to examine the association between hospital infrastructure, resource availability, and processes on early outcomes after cancer surgery worldwide. Methods: A multimethods analysis was performed as part of the GlobalSurg 3 study—a multicentre, international, prospective cohort study of patients who had surgery for breast, colorectal, or gastric cancer. The primary outcomes were 30-day mortality and 30-day major complication rates. Potentially beneficial hospital facilities were identified by variable selection to select those associated with 30-day mortality. Adjusted outcomes were determined using generalised estimating equations to account for patient characteristics and country-income group, with population stratification by hospital. Findings: Between April 1, 2018, and April 23, 2019, facility-level data were collected for 9685 patients across 238 hospitals in 66 countries (91 hospitals in 20 high-income countries; 57 hospitals in 19 upper-middle-income countries; and 90 hospitals in 27 low-income to lower-middle-income countries). The availability of five hospital facilities was inversely associated with mortality: ultrasound, CT scanner, critical care unit, opioid analgesia, and oncologist. After adjustment for case-mix and country income group, hospitals with three or fewer of these facilities (62 hospitals, 1294 patients) had higher mortality compared with those with four or five (adjusted odds ratio [OR] 3·85 [95% CI 2·58–5·75]; p<0·0001), with excess mortality predominantly explained by a limited capacity to rescue following the development of major complications (63·0% vs 82·7%; OR 0·35 [0·23–0·53]; p<0·0001). Across LMICs, improvements in hospital facilities would prevent one to three deaths for every 100 patients undergoing surgery for cancer. Interpretation: Hospitals with higher levels of infrastructure and resources have better outcomes after cancer surgery, independent of country income. Without urgent strengthening of hospital infrastructure and resources, the reductions in cancer-associated mortality associated with improved access will not be realised. Funding: National Institute for Health and Care Research