Charting New Ground: The Ethical Terrain of Nonprofit Journalism

A different kind of revenue, one that has nothing to do with advertising or subscriptions, is playing a larger role in journalism today. Nonprofit funding, once largely the province of public broadcasting, is becoming an important source of support for a new cohort of non-commercial news organizations -- many of them digital natives -- and a growing number of commercial news publishers, which are partnering with nonprofit media and in some cases accepting direct grants themselves. But the ethics of taking grants from foundations and gifts from donors to produce news is still evolving and not without controversy. In New York, a major public TV station returned a large journalism grant for a documentary series because of the donor's connection to the topic being covered. In New Orleans, a nonprofit media organization's reporting about a university president may have cost the organization's its office space at the school. In Texas, a nonprofit established new transparency rules after criticism that it was not revealing enough about donors and event backers. The role of nonprofit media outlets also seems likely to grow. In Philadelphia, the new owner of city's major newspapers is transferring ownership of the publications to a new nonprofit organization, a case being closely watched to see if it might become a model. This report, by the American Press Institute, explores the ethical terrain of nonprofit journalism by examining the kinds of grants made, the nature of communication between funders and grantees, the existence of journalistic firewalls, and the prevalence of written guidelines. The report is based on two main elements: surveys of funders, nonprofit news organizations and commercial partners about a range of funding and ethical issues; and five essays commissioned by people from various media and foundation stakeholder groups that explore different areas of ethical complexity. In a second phase, the study will be followed by recommendations for ethical guidelines

Potomac River Pound-Net Survey Summer 1996: 1996 annual report

This survey had the following goals: (1) collect length and weight data on fishes captured in pound nets in the Potomac River; (2) collect length data of fish captured and released or discarded at-sea; and (3) establish length weight relations in summary statistics to provide baseline data

Potomac River pound-net survey, summers 1996-1997 : 1998 final report

The pound net (Fig 1) is a fixed fishing structure that intercepts fish as they migrate up- or down-river. Fish weirs made of stakes were first used by the Native Americans along the east coast of the English Colonies and were the model for the later development of the pound net. Pound nets were first used in New England around 1850; and were subsequently introduced to Long Island in 1855. A Captain Henry Fitzgerald is reported to have erected the first Chesapeake Bay pound net in 1858, but it failed due to its poor construction. No further attempts were made to use this gear until 1870. At this time two New Jersey fishermen successfully fished a pound net in the James River. A second net was erected in 1875 in the Mob jack Bay, and was so successful that the local fishermen destroyed it. The design of the net was passed around among the fishermen and by 1876 there were 12 nets. So great was the profit that by 1880 there were 162 nets in Virginia (Reid 1955, Austin 1987). The design of the gear has changed little over the years; and during the period between the World Wars the number of nets in the Chesapeake Bay exceeded 2,000. Since the mid-1950\u27s the numbers have declined. June (1956) cited competition with the otter trawl after the mid-1950\u27s as one reason for a general decline in pound nets in the Mid-Atlantic Bight states. (...

A Rapid Synthetic Approach to the ABCD Core of the <i>Stemona </i>Alkaloids

A new Lewis acid-assisted Brønsted acid cascade approach for the stereoselective formation of the tetracyclic Stemona alkaloid skeleton is described in five steps from epoxide 15. Crucially, this tetracyclic product can be accessed as either C13 epimer, potentially serving as intermediates for the synthesis of a range of Stemona alkaloids

Proposing a Pedigree Risk Measurement Strategy: Capturing the Intergenerational Transmission of Antisocial Behavior in a Nationally Representative Sample of Adults

An impressive literature has revealed that variation in virtually every measurable phenotype is the result of a combination of genetic and environmental influences. Based on these findings, studies that fail to use genetically informed modeling strategies risk model misspecification and biased parameter estimates. Twin- and adoption-based research designs have frequently been used to overcome this limitation. Despite the many advantages of such approaches, many available datasets do not contain samples of twins, siblings or adoptees, making it impossible to utilize these modeling strategies. The current study proposes a measurement strategy for estimating the intergenerational transmission of antisocial behavior (ASB) within a nationally representative sample of singletons using an extended pedigree risk approach that relies on information from first- and second-degree relatives. An evaluation of this approach revealed a pattern of findings that directly aligned with studies examining ASB using more traditional twin- and adoption-based research designs. While the proposed pedigree risk approach is not capable of effectively isolating genetic and environmental influences, this overall alignment in results provides tentative evidence suggesting that the proposed pedigree risk measure effectively captures genetic influences. Future replication studies are necessary as this observation remains preliminary. Whenever possible, more traditional quantitative genetic methodologies should be favored, but the presented strategy remains a viable alternative for more limited samples

Polyphenols and Lactobacillus reuteri in oral health

Oral health is one of the necessary preludes to the overall quality of life. Several medical procedures and therapies are available to treat oral diseases in general and periodontal diseases in particular, yet caries, periodontitis, oral cancer, and oral infections remain a global concern. Natural molecules, with their anti-oxidant, anti-inflammatory, and anti-microbic properties, are one of the main sources of oral health and dental health care, and should be supplemented to exploit their beneficial effects. A possible way to improve the intake of these molecules is adhering to a diet that is rich in fruits, vegetables, and probiotics, which has many beneficial properties and can improve overall health and wellbeing. The Mediterranean diet, in particular, provides several beneficial natural molecules, mainly because of the precious nutrients contained in its typical ingredients, mainly plant-based (olives, wine, citrus fruits, and many more). Its beneficial effects on several diseases and in increasing the overall wellbeing of the population are currently being studied by physicians. Among its nutrients, polyphenols (including, among other molecules, lignans, tannins, and flavonoids) seem to be of outmost importance: several studies showed their anticariogenic properties, as well as their effects in decreasing the incidence of non-communicable diseases. Therefore, plant-derived molecules – such as polyphenols – and probiotics – such as Lactobacillus reuteri – have shown a significant potential in treating and curing oral diseases, either alone or in combination, owing to their antioxidant and antimicrobial properties, respectively

Main nutritional deficiencies

Nutrition is the source of energy that is required to carry out all the processes of human body. A balanced diet is a combination of both macro- and micronutrients. “Nutritional inadequacy” involves an intake of nutrients that is lower than the estimated average requirement, whereas “nutritional deficiency” consists of severely reduced levels of one or more nutrients, making the body unable to normally perform its functions and thus leading to an increased risk of several diseases like cancer, diabetes, and heart disease. Malnutrition could be caused by environmental factors, like food scarcity, as well as disease conditions, like anorexia nervosa, fasting, swallowing inability, persistent vomiting, impaired digestion, intestinal malabsorption, or other chronic diseases. Nutritional biomarkers – like serum or plasma levels of nutrients such as folate, vitamin C, B vitamins, vitamin D, selenium, copper, zinc – could be used for the evaluation of nutrient intake and dietary exposure. Macronutrients deficiencies could cause kwashiorkor, marasmus, ketosis, growth retardation, wound healing, and increased infection susceptibility, whereas micronutrient – like iron, folate, zinc, iodine, and vitamin A – deficiencies lead to intellectual impairment, poor growth, perinatal complications, degenerative diseases associated with aging and higher morbidity and mortality. Preventing macro- and micronutrient deficiency is crucial and this could be achieved through supplementation and food-based approache

Metabolomics application for the design of an optimal diet

Precision nutrition is an emerging branch of nutrition science that aims to use modern omics technologies (genomics, proteomics, and metabolomics) to assess an individual’s response to specific foods or dietary patterns and thereby determine the most effective diet or lifestyle interventions to prevent or treat specific diseases. Metabolomics is vital to nearly every aspect of precision nutrition. It can be targeted or untargeted, and it has many applications. Indeed, it can be used to comprehensively characterize the thousands of chemicals in foods, identify food by-products in human biofluids or tissues, characterize nutrient deficiencies or excesses, monitor biochemical responses to dietary interventions, track long- or short-term dietary habits, and guide the development of nutritional therapies. Indeed, metabolomics can be coupled with genomics and proteomics to study and advance the field of precision nutrition. Integrating omics with epidemiological and clinical data will begin to define the beneficial effects of human food metabolites. In this review, we present the metabolome and its relationship to precision nutrition. Moreover, we describe the different techniques used in metabolomics and present how metabolomics has been applied to advance the field of precision nutrition by providing notable examples and cases