20 research outputs found

    The Champlain Thrust and Related Features Near Middlebury,Vermont

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    Guidebook for field trips in Vermont: 64th annual meeting October 13, 14, 15, 1972 Burlington, Vermont: Trip B-

    Treating the placenta to prevent adverse effects of gestational hypoxia on fetal brain development.

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    Some neuropsychiatric disease, including schizophrenia, may originate during prenatal development, following periods of gestational hypoxia and placental oxidative stress. Here we investigated if gestational hypoxia promotes damaging secretions from the placenta that affect fetal development and whether a mitochondria-targeted antioxidant MitoQ might prevent this. Gestational hypoxia caused low birth-weight and changes in young adult offspring brain, mimicking those in human neuropsychiatric disease. Exposure of cultured neurons to fetal plasma or to secretions from the placenta or from model trophoblast barriers that had been exposed to altered oxygenation caused similar morphological changes. The secretions and plasma contained altered microRNAs whose targets were linked with changes in gene expression in the fetal brain and with human schizophrenia loci. Molecular and morphological changes in vivo and in vitro were prevented by a single dose of MitoQ bound to nanoparticles, which were shown to localise and prevent oxidative stress in the placenta but not in the fetus. We suggest the possibility of developing preventative treatments that target the placenta and not the fetus to reduce risk of psychiatric disease in later life

    Measurement of W and Z boson production cross sections

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    DO has measured the inclusive production cross section of W and Z bosons in a sample of 13 pb1^{-1} of data collected at the Fermilab Tevatron. The cross sections, multiplied by their leptonic branching fractions, for production in pbar-p collisions at sqrt{s}=1.8 TeV are sigma_W*B(W->e nu) = 2.36+-0.02+-0.08+-0.13 nb, sigma_W*B(W->mu nu) = 2.09+-0.06+-0.22+-0.11 nb, sigma_Z*B(Z->e+ e-) = 0.218+-0.008+-0.008+-0.012 nb, and sigma_Z*B(Z->mu+ mu-) = 0.178+-0.022+-0.021+-0.009 nb, where the first uncertainty is statistical and the second systematic; the third reflects the uncertainty in the integrated luminosity. For the combined electron and muon analyses, we find sigma_W*B(W->l mu)/sigma_Z*B(Z->l+ l-) = 10.90+-0.52. Assuming standard model couplings, we use this result to determine the width of the W boson, and obtain Gamma(W) = 2.044+-0.097 GeV.Comment: 46 pages with 17 embedded figures, submitted to PRD, Run 1a result

    Plate Tectonic Constraints on the Biogeography of Middle America and the Caribbean Region

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    Volume: 69Start Page: 432End Page: 44

    Plate tectonics of the Ancestral Rocky Mountains

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    The Ancestral Rocky Mountains were intracratonic block uplifts that formed in Colorado and the surrounding region during Pennsylvanian time. Their development related to the collision of North America with South America–Africa, which produced the Ouachita-Marathon orogeny. In Early Pennsylvanian time, suturing was taking place only in the Ouachita region, and foreland deformation took place only in the mid-continent. By Middle Pennsylvanian time, the length of the suture zone had increased, and it was active from the Ouachita to the Marathon region. The extent of cratonic deformation also increased in intensity and in areal extent, culminating in the Ancestral Rocky Mountains. In Late Pennsylvanian time, suturing was taking place only in the Marathon region, and cratonic deformation decreased in extent and spread southward into New Mexico and West Texas. We suggest that the Ancestral Rocky Mountains, and related features over a broad area of the western United States, were formed while an irregularly bounded peninsula of the craton (including the transcontinental arch) was pushed northwestward by the progressive collision-suturing of North America and South America–Africa. This intraplate deformation is, in some respects, like the deformation of Asia in response to the Cenozoic collision with India

    The Finisterra-Léon-Mid German Cristalline Rise Domain; Proposal of a New Terrane in the Variscan Chain

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    This chapter characterizes the Finisterra Terrane, enhancing its differences from the neighbouring Iberian Terrane. The contact between these terranes is the Porto- Tomar-Ferreira do Alentejo Shear Zone, a major lithospheric structure whose complex Variscan evolution remains debatable. The lithostratigraphic, tectonometamorphic and magmatic features observed in the Finisterra Terrane show that it was an independent terrane during the Devonian. This situation changed during the Mississippian, when the main features of the Finisterra and the Iberian Terranes became similar, which indicates that both terranes evolved together since the Carboniferous times. The similarities of the Finisterra Terrane with the Central European Variscan domains, namely the Léon Block and the Mid-German Crystalline Rise, enable us to propose a new tectono-stratigraphic terrane (Finisterra-León-MGCR Terrane), which defines an arcuate pattern compatible with the Ibero-Armorican Arc
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