Bodybuilders\u27 Knowledge and Perceptions of the Use of Anabolic Steroids

This study addressed the following questions: 1. What knowledge do bodybuilders have regarding the positive and negative effects of anabolic steroids? 2. What is the perception of bodybuilders regarding the positive and negative effects of anabolic steroids

Terrestrial heat flow in North Central United States.

Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Earth and Planetary Sciences, 1970.Vita.Bibliography: leaves 209-220.Ph.D

A Synthesis of Resource and Governance Theories in the Context of Horizontal Expansion Strategies.

Extant literature has yet to fully examine the antecedents to, and performance implications of, horizontal expansion strategies. Defined as strategies that increase a firm\u27s domain within an industry, these business level strategies constitute an important component of a firm\u27s overall scope. This study takes a complementary view of two theories of the firm--resource theory and governance theory--in order to explain horizontal strategy and performance. An empirical investigation of 101 restaurant chains shows that firms respond to governance cost pressures when choosing among alternative horizontal strategies, except when strategically valuable resource stocks are low. However, no clear link was found between this strategic behavior and performance. The interaction between resources and governance furnishes a stronger explanation of horizontal strategic choice than previous research grounded in either theory alone. Furthermore, one-way relationships identified by prior research may need to be re-evaluated

Wheels are Rollin\u27

No cover arthttps://scholarsjunction.msstate.edu/cht-sheet-music/11094/thumbnail.jp

Team Spirit: How Three Libraries Are Working to Support Health Sciences Libraries in Liberia

This poster presentation is a collaborative effort of librarians from Lamar Soutter Library, University of Massachusetts Medical School; Himmelfarb Health Sciences Library, The George Washington University; and Louis Stokes Health Sciences Library, Howard University. International medicine initiatives often occur through institution specific efforts. Yet information needs extend across borders and institutions. Three American health sciences libraries have united to support the development of health sciences libraries in Liberia. While separate schools will support undergraduate and graduate medical education initiatives, the libraries are working together to bring current information resources to all health care professionals

A Study of Nektonic and Benthic Faunas of the Shallow Gulf of Mexico Off the State of Mississippi As Related to Some Physical, Chemical, and Geological Factors

A seasonal study of the nektonic and benthic faunas of the shallow Gulf of Mexico off Mississippi was conducted from January 1967 through May 1969. It was planned to sample monthly six fixed offshore stations at depths ranging from 5 to 50 fathoms in the open Gulf. In general this was carried out fairly well. Water samples were taken from surface, midwater, and bottom levels each time a station was occupied, and temperatures and salinities were recorded for each of these. Samples were tested for the presence of nitrates, nitrites, ortho-phosphates and total phosphates. Secchi disc extinction points were recorded. Grab samples were taken for the determination of bottom composition. Plankton samples were taken from surface, midwater and bottom levels. Copepods, brachyuran zoea and megalops, stomatopod larvae, Lucifer faxoni, Acetes a. carolinae, Penilia avirostris, Doliolum sp. and fish eggs and larvae were present in greatest abundance. Surface and benthic nekton samples were obtained. Dredge samples were made quarterly and twelve invertebrate species and three species of fishes were collected. Renilla mülleri was the most abundant species taken, and the fish catch consisted of Centropristes ocyurus, Citharichthys spilopterus and Etropus crossotus. Accounts of 50 invertebrate species (24,679 specimens) and 129 fishes (93,563 specimens) taken in trawl hauls is presented. Temperature and salinity data are given for all species. Relative abundance, seasonal bathymetric distributions and movements, apparent growth patterns, catch per unit of effort and various biological data are noted for the most abundant species. Station 5 (40 fathoms) produced the largest percentage of trawl catches (22.7). Renilla mülleri was the most abundant invertebrate taken in trawling. The brown shrimp, Penaeus aztecus, was second in abundance (10.92%). The five most abundant species comprising 80.57% numerically of the catch were croaker, longspine porgy, butterfish, spot, and seatrout. The species comprising 91.89% of the catch by weight were the croaker, longspine porgy, spot, seatrout, lizardfish, butterfish, pinfish, bank sea bass, sea catfish and black fin sea robin. The families Sciaenidae, Sparidae and Stromateidae were represented by the greatest numbers and comprised 82.9% of the total catch. Families considered to be of commercial importance contributed 92.9% to the total fish catch

Configuration development study of the X-24C hypersonic research airplane

Bottom line results were made of a three-phase study to determine the feasibility of designing, building, and operating, and maintaining an air-launched high performance aircraft capable of cruising at speeds up to Mach 8 for short durations. The results show that Lockalloy heat-sink structure affords the capability for a 'work-horse' vehicle which can serve as an excellent platform for this research. It was further concluded that the performance of a blended wing body configuration surpassed that of a lifting body design for typical X-24C missions. The cost of a two vehicle program, less engines, B-52 modification and contractor support after delivery, can be kept within $70M (in Jan. 1976 dollars)

Are the average gait speeds during the 10 meter and 6 minute walk tests redundant in Parkinson disease?

Published in final edited form as: Gait Posture. 2017 February ; 52: 178–182. doi:10.1016/j.gaitpost.2016.11.033.We investigated the relationships between average gait speed collected with the 10Meter Walk Test (Comfortable and Fast) and 6Minute Walk Test (6MWT) in 346 people with Parkinson disease (PD) and how the relationships change with increasing disease severity. Pearson correlation and linear regression analyses determined relationships between 10Meter Walk Test and 6MWT gait speed values for the entire sample and for sub-samples stratified by Hoehn & Yahr (H&Y) stage I (n=53), II (n=141), III (n=135) and IV (n=17). We hypothesized that redundant tests would be highly and significantly correlated (i.e. r>0.70, p<0.05) and would have a linear regression model slope of 1 and intercept of 0. For the entire sample, 6MWT gait speed was significantly (p<0.001) related to the Comfortable 10 Meter Walk Test (r=0.75) and Fast 10Meter Walk Test (r=0.79) gait speed, with 56% and 62% of the variance in 6MWT gait speed explained, respectively. The regression model of 6MWT gait speed predicted by Comfortable 10 Meter Walk gait speed produced slope and intercept values near 1 and 0, respectively, especially for participants in H&Y stages II-IV. In contrast, slope and intercept values were further from 1 and 0, respectively, for the Fast 10Meter Walk Test. Comfortable 10 Meter Walk Test and 6MWT gait speeds appeared to be redundant in people with moderate to severe PD, suggesting the Comfortable 10 Meter Walk Test can be used to estimate 6MWT distance in this population.This study was funded by the Davis Phinney Foundation, the Parkinson's Disease Foundation, and the National Institutes of Health (R01 NS077959, K12 HD055931, UL1 TR000448). The funding sources had no input related to study design, data collection, or decision to submit for publication. (Davis Phinney Foundation; Parkinson's Disease Foundation; R01 NS077959 - National Institutes of Health; K12 HD055931 - National Institutes of Health; UL1 TR000448 - National Institutes of Health

Wnt/β-catenin signaling is required for development of the exocrine pancreas

BACKGROUND: β-catenin is an essential mediator of canonical Wnt signaling and a central component of the cadherin-catenin epithelial adhesion complex. Dysregulation of β-catenin expression has been described in pancreatic neoplasia. Newly published studies have suggested that β-catenin is critical for normal pancreatic development although these reports reached somewhat different conclusions. In addition, the molecular mechanisms by which loss of β-catenin affects pancreas development are not well understood. The goals of this study then were; 1] to further investigate the role of β-catenin in pancreatic development using a conditional knockout approach and 2] to identify possible mechanisms by which loss of β-catenin disrupts pancreatic development. A Pdx1-cre mouse line was used to delete a floxed β-catenin allele specifically in the developing pancreas, and embryonic pancreata were studied by immunohistochemistry and microarray analysis. RESULTS: Pdx1-cre floxed β-catenin animals were viable but demonstrated small body size and shortened median survival. The pancreata from knockout mice were hypoplastic and histologically demonstrated a striking paucity of exocrine pancreas, acinar to duct metaplasia, but generally intact pancreatic islets containing all lineages of endocrine cells. In animals with extensive acinar hypoplasia, putative hepatocyte transdifferention was occasionally observed. Obvious and uniform pancreatic hypoplasia was observed by embryonic day E16.5. Transcriptional profiling of Pdx1-cre floxed β-catenin embryonic pancreata at E14.5, before there was a morphological phenotype, revealed significant decreases in the β-catenin target gene N-myc, and the basic HLH transcription factor PTF1, and an increase of several pancreatic zymogens compared to control animals. By E16.5, there was a dramatic loss of exocrine markers and an increase in Hoxb4, which is normally expressed anterior to the pancreas. CONCLUSION: We conclude that β-catenin expression is required for development of the exocrine pancreas, but is not required for development of the endocrine compartment. In contrast, β-catenin/Wnt signaling appears to be critical for proliferation of PTF1+ nascent acinar cells and may also function, in part, to maintain an undifferentiated state in exocrine/acinar cell precursors. Finally, β-catenin may be required to maintain positional identity of the pancreatic endoderm along the anterior-posterior axis. This data is consistent with the findings of frequent β-catenin mutations in carcinomas of acinar cell lineage seen in humans