69 research outputs found

    Las Exposiciones de 1929 en la prensa española no especializada."Todo es belleza y paradoja en este pabellón"

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    Las Exposiciones Universales han albergado a lo largo del siglo XX algunos de los ejemplos más relevantes de arquitectura moderna. La atención sobre estos eventos por parte de la prensa generalista ha servido históricamente como vehículo de difusión de la arquitectura moderna. Las exposiciones celebradas en España en 1929 supusieron uno de los primeros ejemplos de este fenómeno de divulgación entre el público no especializado.The year 1929 is a key moment in the evolution of “modern” architecture in Spain. The incipient avant-garde movements had had few opportunities to make themselves known by the general public, beyond some specific experiences. For a few months, the country became the center of international architectural interest thanks to twoexhibitions in Barcelona and Seville. The architecture proposed in both events has been the subject of numerous studies. The aim of this paper is to study how non-specialized press helped to disseminate these architectural proposals among its readers, not used to the tendencies of modern architecture. It has been analysed the impact of the two most important newspapers of the time, ABC and La Vanguardia. Although most of the architecture exhibited was still influenced by the eclectic tradition of the 19th Century, the subjects addressed in the articles and, mainly , the way in which they were written, allow us to contemplate how Spanish society began to know the architecture proposed by the avant-gardes. In this way,the German pavilion of Mies van der Rohe of the Barcelona exhibition became the first purely modern example that got through to the Spanish public by the pages of the daily press

    Middle Ordovician harknessellid brachiopods (Dalmanellidina) from the Mediterranean margin of Gondwana

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    The family Harknessellidae Bancroft, 1928 (Orthida, Dalmanellidina) was designed to embrace an assemblage of species referred previously to Harknessella Reed, 1917, and included five genera known mainly from the Middle and Upper Ordovician of England. Herein, we suggest reassigning to this family the genus Cacemia Mitchell, 1974, widespread in the middle Darriwilian (upper Middle Ordovician) of the Iberian and Armorican massifs. Since its designation, Cacemia was placed among the dalmanellidin heterorthids, in spite of its strongly mucronate hinge line, which is totally unknown within this Mediterranean family. A new harknessellid has been identified from the upper Darriwilian beds of the Central Iberian Zone (Central Spain): Isabelella fascicostellata Reyes-Abril Villas gen. et sp. nov. It is similar to Horderleyella Bancroft, 1928 for its coarsely fascicostellate radial ornamentation and obtuse cardinal angles, although its convexoplane to convexoconcave profile allows discrimination from the typically dorsibiconvex Horderleyella. A phylogenetic analysis of the family places both Cacemia and Isabelella in basal positions of their clades, which fits with their early stratigraphic record. Based on our study, the family Harknessellidae appears to have originated in the high latitude Mediterranean margins of Gondwana during pre-Darriwilian times, before the detachment of Avalonia from Gondwana. The family reached its highest diversification in Avalonia throughout the Late Ordovician, keeping connections with the Mediterranean and Proto-Andean margins of Gondwana, as well as with the mid-latitude palaeocontinents of Baltica and South China

    Middle Ordovician harknessellid brachiopods (Dalmanellidina) from the Mediterranean margin of Gondwana

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    The family Harknessellidae Bancroft, 1928 (Orthida, Dalmanellidina) was designed to embrace an assemblage of species referred previously to Harknessella Reed, 1917, and included five genera known mainly from the Middle and Upper Ordovician of England. Herein, we suggest reassigning to this family the genus Cacemia Mitchell, 1974, widespread in the middle Darriwilian (upper Middle Ordovician) of the Iberian and Armorican massifs. Since its designation, Cacemia was placed among the dalmanellidin heterorthids, in spite of its strongly mucronate hinge line, which is totally unknown within this Mediterranean family. A new harknessellid has been identified from the upper Darriwilian beds of the Central Iberian Zone (Central Spain): Isabelella fascicostellata Reyes-Abril Villas gen. et sp. nov. It is similar to Horderleyella Bancroft, 1928 for its coarsely fascicostellate radial ornamentation and obtuse cardinal angles, although its convexoplane to convexoconcave profile allows discrimination from the typically dorsibiconvex Horderleyella. A phylogenetic analysis of the family places both Cacemia and Isabelella in basal positions of their clades, which fits with their early stratigraphic record. Based on our study, the family Harknessellidae appears to have originated in the high latitude Mediterranean margins of Gondwana during pre-Darriwilian times, before the detachment of Avalonia from Gondwana. The family reached its highest diversification in Avalonia throughout the Late Ordovician, keeping connections with the Mediterranean and Proto-Andean margins of Gondwana, as well as with the mid-latitude palaeocontinents of Baltica and South China.Peer Reviewe

    EphrinA4 plays a critical role in α4 and αL mediated survival ofhuman CLL cells during extravasation

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    A role of endothelial cells in the survival of CLL cells during extravasation is presently unknown. Herein we show that CLL cells but not normal B cells can receive apoptotic signals through physical contact with TNF-α activated endothelium impairing survival in transendothelial migration (TEM) assays. In addition, the CLL cells of patients having lymphadenopathy (LApos) show a survival advantage during TEM that can be linked to increased expression of α4 and αL integrin chains. Within this context, ephrinA4 expressed on the surface of CLL cells sequestrates integrins and inactivates them resulting in reduced adhesion and inhibition of apoptotic/survival signals through them. In agreement, ephrinA4 silencing resulted in increased survival of CLL cells of LApos patients but not LA neg patients. Similarly was observed when a soluble ephrinA4 isoform was added to TEM assays strongly suggesting that accumulation of this isoform in the serum of LApos patients could contribute to CLL cells dissemination and survival in vivo. In supporting, CLL lymphadenopathies showed a preferential accumulation of apoptotic CLL cells around high endothelial venules lacking ephrinA4. Moreover, soluble ephrinA4 isolated from sera of patients increased the number and viability of CLL cells recovered from the lymph nodes of adoptively transferred mice. Finally, we present evidence suggesting that soluble ephrinA4 mediated survival during TEM could enhance a transcellular TEM route of the CLL cells. Together these findings point to an important role of ephrinA4 in the nodal dissemination of CLL cells governing extravasation and survival

    The first fossil assemblage from the Ordovician of Águeda (Aveiro): litho and biostratigraphic implications

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    RESUMO: Apresentam-se os primeiros fósseis do Ordovícico de Águeda, provenientes de níveis de meta-argilitos intercalados numa sequência arenítica metamórfica de Arrancada do Vouga. A associação, moderadamente diversa, inclui trilobites [Crozonaspis cf. incerta (Deslongchamps) e Crozonaspis sp.], bivalves [Praenucula sp., Cardiolaria cf. beirensis (Sharpe), Praeleda cf. ribeiroi (Sharpe), Hemiprionodonta cf. lusitanica (Sharpe), Tancrediopsis escosurae? (Sharpe) e Myoplusia? sp.], gastrópodes (Bellerophontidae indet. e Platyceratidae indet.), braquiópodes (Heterorthina sp.), ostracodos (Conchoprimitia? sp.) e quitinozoários (Desmochitina minor Eisenack), os quais indicam a idade Dobrotiviano superior (ca. Darriwiliano superior Sandbiano inferior). A sequência metarenítica descrita apresenta afinidades com a Formação Cabril da Zona Centro-Ibérica de Portugal central. Do ponto de vista bio e litostratigráfico, a sucessão ordovícica de Águeda apresenta uma maior afinidade com os setores meridionais da ZCI, e não com o setor norte (e.g. Valongo), contrariamente às restantes áreas incluídas na faixa de cisalhamento Porto – Albergaria-a-Velha.ABSTRACT: The first Ordovician fossils from Águeda are presented, coming from dark mudstones between two sandstones successions at Arrancada do Vouga. The moderately diverse assemblage includes trilobites [Crozonaspis cf. incerta (Deslongchamps) and Crozonaspis sp.], bivalves [Praenucula sp., Cardiolaria cf. beirensis (Sharpe), Praeleda cf. ribeiroi (Sharpe), Hemiprionodonta cf. lusitanica (Sharpe), Tancrediopsis escosurae? (Sharpe) and Myoplusia? sp.], gastropods (Bellerophontidae indet. and Platyceratidae indet.), brachiopods (Heterorthina sp.), ostracods (Conchoprimitia? sp.) and chitinozoans (Desmochitina minor Eisenack), which indicate an upper Dobrotivian (ca. upper Darriwilian-lower Sandbian) age. The described succession shows affinities with the Cabril Formation, occurring in the Central Iberian Zone of central Portugal. From a bio- and lithostratigraphic point of view, the Águeda Ordovician sequence has a greater affinity with the southern of the ZCI, and not the northern sector (e.g. Valongo), contrary to the other areas included in the Porto-Albergaria-a-Velha shear zone.info:eu-repo/semantics/publishedVersio

    Modeling the Spanish Bachillerato academic underachievement using a random network

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    Creative Commons: Atribución 3.0 España (CC BY 3.0 ES)[EN] In this paper, we propose a random network to model the evolution of the academic performance focused on the educational level of Bachillerato in Spain. For that, we will build a random network. Once the random network is stated, it will evolve according to a set of evolution rules and this allows us to simulate the academic behavior of Bachillerato students in order to determine whether they promote or not to the next academic level. Finally, this simulation process will allow us to provide predictions given by 95% of confidence intervals of the Bachillerato academic results over the next few years. Our predictions provide good results since, for each academic subpopulation, the new real data appeared during the development of this study corresponding to the academic year 2009 − 2010 lie inside the confidence intervals.Cortés López, JC.; Colmenar, JM.; Hidalgo, I.; Sánchez Sanchez, A.; Santonja, F.; Villanueva Micó, RJ. (2014). Modeling the Spanish Bachillerato academic underachievement using a random network. International Journal of Complex Systems in Science. 4(1):7-11. http://hdl.handle.net/10251/60001S7114

    Aplicaciones y seguridad en la implementación de competencias prácticas en entornos de gestión del aprendizaje

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    In this article, some improvements and contributions are introduced into two main features of the Learning Management Systems (LMSs). The first feature is the security and the authentication functionality, where we present a model that combines the traditional authentication based on username and password, with the authentication based on fingerprints. The second feature is the access to remote and virtual laboratories, where we present a middleware architecture that combines the duplicated services provided by both, the laboratories and the LMS, in order to facilitate their integration and to provide a unique access from the LMS to the remote and virtual laboratories.En este artículo exponemos algunas mejoras y aportaciones en dos aspectos de los sistemas de gestión de aprendizaje (LMS). El primer aspecto es la seguridad y la autenticación, donde presentamos una modalidad de combinar la autenticación tradicional de contraseña y nombre de usuario con la autenticación por la técnica biométrica de comparación de huellas dactilares. El segundo aspecto es una arquitectura middleware capaz de dar acceso desde los LMS a distintos laboratorios remotos y virtuales (online) de forma que, se evita la duplicación de los servicios proporcionados por ambas y se reutilizan los servicios proporcionados por los LMS en las sesiones prácticas
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