219 research outputs found
Teachers’ Goals, Mindsets, and Formalized Teacher Leader Credentials
Teachers across New Jersey (NJ) are advancing within the profession as teacher leaders. The problem addressed in this study is that there is a gap in knowledge regarding what goals and mindsets motivate NJ teachers to engage in teacher leadership (TL) and seek formal teacher leader credentials. The purpose of this quantitative study was to explore the relationship between teachers’ work goal orientation (WGO) and the mindset measure kind of person (KOP) as well as understand how these variables predict aspiration to engage in TL and highest aspiration for a formal teacher leader credential. The goal orientation theory was used for this correlational study, where NJ teachers were invited through purposive sampling (n = 112) to take Brett and Vandewalle’s WGO instrument and Dweck’s KOP implicit theory scale. This study involved exploring whether WGO learning, proving, avoiding, and KOP scores predict aspiration to engage in TL; binomial logistic regression analysis showed for every increase in the mean of WGO learning score, participants were 4.663 more likely to aspire to engage in TL. This study also involved exploring whether WGO learning, proving, avoiding, and KOP scores predict highest aspiration for a formal teacher leader credential; ordinal logistic regression analysis showed for just one mean score increase in WGO learning score, the probability of aspiring to earn a formalized teacher leader credential increases 2.591 times. Positive social change may result if teachers with a WGO learning goal orientation (LGO) are attracted and retained into the profession through teacher leadership opportunities and training
Importance Of SBIRT Training In Undergraduate Curriculum
Research poster detailing investigation of the question: What is the significance of Screening, Brief Intervention and Referral to Treatment (SBIRT) and why is it important to implement in undergrad curriculum?https://dune.une.edu/cecespring2020/1000/thumbnail.jp
Percutaneous Coronary Intervention in Patients With a History of Gastrointestinal Bleeding (From the Blue Cross Blue Shield of Michigan Cardiovascular Consortium)
Potent antithrombotic agents are routinely prescribed after percutaneous coronary intervention (PCI) to reduce ischemic complications. However, in patients who are at an increased bleeding risk, this may pose significant risks. We sought to evaluate the association between a history of gastrointestinal bleeding (GIB) and outcomes after PCI. We linked clinical registry data from PCIs performed at 48 Michigan hospitals between 1/2013 and 3/2018 to Medicare claims. We used 1:5 propensity score matching to adjust for patient characteristics. In-hospital outcomes included bleeding, transfusion, stroke or death. Post-discharge outcomes included 90-day all-cause readmission and long-term mortality. Of 30,206 patients, 1.1% had a history of GIB. Patients with a history of GIB were more likely to be older, female, and have more cardiovascular comorbidities. After matching, those with a history of GIB (n = 312) had increased post-procedural transfusions (15.7% vs 8.4%; p \u3c 0.001), bleeding (11.9% vs 5.2%; p \u3c 0.001), and major bleeding (2.8% vs 0.6%; p = 0.004). Ninety-day readmission rates were similar among those with and without a history of GIB (34.3% vs 31.3%; p = 0.318). There was no significant difference in post-discharge survival (1 year: 78% vs 80%; p = 0.217; 5 years: 54% vs 51%; p = 0.189). In conclusion, after adjusting for baseline characteristics, patients with a history of GIB had increased risk of post-PCI in-hospital bleeding complications. However, a history of GIB was not significantly associated with 90-day readmission or long-term survival
Changes in stress pathways as a possible mechanism of aerobic exercise training on brain health: a scoping review of existing studies
Physical activity (PA) in the form of aerobic exercise (AE) preserves and improves neurocognitive function across the lifespan. However, a mechanistic understanding of the pathways by which aerobic exercise impacts brain health is still lacking, particularly with respect to stress-related pathways. One mechanistic hypothesis is that AE improves neurocognitive health in part by modifying circulating levels of stress-related hormones and signaling factors associated with the hypothalamic-pituitary-adrenal (HPA) axis and autonomic nervous system (ANS), as commonly measured by the biomarkers cortisol (CORT) and salivary α-amylase (sAA). Thus, this hypothesis predicts that changes in stress biomarkers, such as CORT and sAA, are possible explanatory pathways mediating the positive effects of AE on neurocognitive health. In the present review article, we provide a summary of available studies examining the possibility that exercise-induced changes to stress biomarkers could partly account for exercise-related improvements in neurocognitive health. Our review indicates that despite the intuitive appeal of this hypothesis, there is insufficient evidence available to conclude that chronic and habitual AE affects neurocognitive health by altering stress biomarker pathways. The cross-sectional nature of the majority of reviewed studies highlights the need for well-controlled studies to adequately test this hypothesis
Return to performance following severe ankle, knee, and hip injuries in National Basketball Association players
Abstract The purpose of this study was to compare basketball performance markers one year prior to initial severe lower extremity injury, including ankle, knee, and hip injuries, to one- and two-years following injury during the regular NBA season. Publicly available data were extracted through a reproducible extraction computed programmed process. Eligible participants were NBA players with at least three seasons played between 2008 and 2019, with a time-loss injury reported during the study period. Basketball performance was evaluated for season minutes, points, and rebounds. Prevalence of return to performance and linear regressions were calculated. 285 athletes sustained a severe lower extremity injury. 196 (69%) played one year and 130 (45%) played two years following the injury. Time to return to sport was similar between groin/hip/thigh [227 (88)], knee [260 (160)], or ankle [260 (77)] (P = 0.289). 58 (30%) players participated in a similar number of games and 57 (29%) scored similar points one year following injury. 48 (37%) participated in a similar number of games and 55 (42%) scored a similar number of points two years following injury. Less than half of basketball players that suffered a severe lower extremity injury were participating at the NBA level two years following injury, with similar findings for groin/hip/thigh, knee, and ankle injuries. Less than half of players were performing at previous pre-injury levels two years following injury. Suffering a severe lower extremity injury may be a prognostic factor that can assist sports medicine professionals to educate and set performance expectations for NBA players
A Habitable-zone Earth-sized Planet Rescued from False Positive Status
We report the discovery of an Earth-sized planet in the habitable zone of a
low-mass star called Kepler-1649. The planet, Kepler-1649 c, is
1.06 times the size of Earth and transits its 0.1977 +/-
0.0051 Msun mid M-dwarf host star every 19.5 days. It receives 74 +/- 3 % the
incident flux of Earth, giving it an equilibrium temperature of 234 +/- 20K and
placing it firmly inside the circumstellar habitable zone. Kepler-1649 also
hosts a previously-known inner planet that orbits every 8.7 days and is roughly
equivalent to Venus in size and incident flux. Kepler-1649 c was originally
classified as a false positive by the Kepler pipeline, but was rescued as part
of a systematic visual inspection of all automatically dispositioned Kepler
false positives. This discovery highlights the value of human inspection of
planet candidates even as automated techniques improve, and hints that
terrestrial planets around mid to late M-dwarfs may be more common than those
around more massive stars.Comment: 11 pages, 3 figures, 1 table. Accepted for publication in ApJ
The occurrence of small, short-period planets younger than 200 Myr with TESS
Within the first few hundreds of millions of years, many physical processes
sculpt the eventual properties of young planets. NASA's TESS mission has
surveyed young stellar associations across the entire sky for transiting
planets providing glimpses into the various stages of planetary evolution.
Using our own detection pipeline, we search a magnitude-limited sample of 7219
young stars (200 Myr) observed in the first four years of TESS for small
(2-8 R), short period (1.6-20 days) transiting planets. The
completeness of our survey is characterized by a series of injection and
recovery simulations. Our analysis of TESS 2-minute cadence and Full Frame
Image (FFI) light curves recover all known TOIs, as well as four new planet
candidates not previously identified as TOIs. We derive an occurrence rate of
% for mini-Neptunes and % for super-Neptunes
from the 2-minute cadence data, and % for mini-Neptunes and
% for super-Neptunes from FFI data. To independently validate
our results, we compare our survey yield with the predicted planet yield
assuming Kepler planet statistics. We consistently find a mild increase in the
occurrence of super-Neptunes and a significant increase in the occurrence of
Neptune-sized planets with orbital periods of 6.2-12 days when compared to
their mature counterparts. The young planet distribution from our study is most
consistent with evolution models describing the early contraction of
hydrogen-dominated atmospheres undergoing atmospheric escape and inconsistent
with heavier atmosphere models offering only mild radial contraction early on.Comment: Accepted to AJ. Updated version after proofing. 24 pages, 13 figures,
3 table
Elbow Injuries Among MLB Pitchers Increased During Covid-19 Disrupted Season, But Not Other Baseball Injuries
# Background
The 2020 Major League Baseball Season (MLB) demonstrated season disruptions due to the COVID-19 pandemic. Changes in training and seasonal time frames may be associated with higher rates of injury.
# Purpose
To use publicly available data to compare injury rates during the 2015-2019 seasons, COVID-19 shortened season (2020), and the 2021 season stratified by body region and position (pitchers versus position players).
# Study Design
A retrospective cohort study utilizing publicly available data
# Methods
MLB players who competed in 1+ seasons between 2015-2021 were included and stratified by position (pitcher, position player). Incidence rate (IR), reported by 1000 x Athlete-Game Exposures (AGEs), was calculated for each season, and stratified by position and body region. Poisson regressions were performed for all injuries and stratified by position to determine association between season and injury incidence. Subgroup analyses were performed on the elbow, groin/hip/thigh, shoulder.
# Results
Four thousand, two hundred and seventy-four injuries and 796,502 AGEs across 15,152 players were documented. Overall IR was similar across seasons (2015-2019:5.39; 2020:5.85; 2021:5.04 per 1000 AGEs). IR remained high for the groin/hip/thigh for position players (2015-2019:1.7; 2020:2.0; 2021:1.7 per 1000 AGEs). There was no difference in injury rates between 2015-2019 and 2020 seasons . The 2020 season demonstrated a significant increase in elbow injuries 2.7 (1.8-4.0), p\<0.001; when stratified by position, this increase remained significant for pitchers pitchers: 3.5 (2.1-5.9), p\<0.001; position players: 1.8 (0.9-3.6), p=0.073. No other differences were observed.
# Conclusion
The groin/hip/thigh demonstrated the highest IR in 2020 among position players across all season time frames, indicating that continued injury mitigation for this region is necessary. When stratified by body region, elbow injury rates among pitchers demonstrated 3.5 times the rate of injury in 2020 compared to previous seasons, impacting injury burden for the most vulnerable body region among pitchers.
# Level of Evidence
Level II
Whole Genome Sequence Analysis of Burkholderia contaminans FFH2055 Strain Reveals the Presence of Putative β-Lactamases
Burkholderia contaminans is a member of the Burkholderia cepacia complex (Bcc), a pathogen with increasing prevalence among cystic fibrosis (CF) patients and the cause of numerous outbreaks due to the use of contaminated commercial products. The antibiotic resistance determinants, particularly β-lactamases, have been poorly studied in this species. In this work, we explored the whole genome sequence (WGS) of a B. contaminans isolate (FFH 2055) and detected four putative β-lactamase-encoding genes. In general, these genes have more than 93% identity with β-lactamase genes found in other Bcc species. Two β-lactamases, a class A (Pen-like, suggested name PenO) and a class D (OXA-like), were further analyzed and characterized. Amino acid sequence comparison showed that Pen-like has 82% and 67% identity with B. multivorans PenA and B. pseudomallei PenI, respectively, while OXA-like displayed strong homology with class D enzymes within the Bcc, but only 22–44% identity with available structures from the OXA family. PCR reactions designed to study the presence of these two genes revealed a heterogeneous distribution among clinical and industrial B. contaminans isolates. Lastly, bla PenO gene was cloned and expressed into E. coli to investigate the antibiotic resistance profile and confers an extended-spectrum β-lactamase (ESBL) phenotype. These results provide insight into the presence of β-lactamases in B. contaminans, suggesting they play a role in antibiotic resistance of these bacteria.Fil: Degrossi, José J.. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica; ArgentinaFil: Merino, Cindy. University Fullerton; Estados UnidosFil: Isasmendi, Adela M.. Gobierno de la Ciudad de Buenos Aires. Hospital de Pediatría "Juan P. Garrahan"; ArgentinaFil: Ibarra, Lorena M.. Gobierno de la Ciudad de Buenos Aires. Hospital General de Niños "Ricardo Gutiérrez"; ArgentinaFil: Collins, Chelsea. University Fullerton; Estados UnidosFil: Bo, Nicolás E.. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica; ArgentinaFil: Papalia, Mariana Andrea. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Departamento de Microbiología, Inmunología y Biotecnología. Cátedra de Microbiología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay; ArgentinaFil: Fernandez, Jennifer S.. University Fullerton; Estados UnidosFil: Hernandez, Claudia M.. Gobierno de la Ciudad de Buenos Aires. Hospital de Pediatría "Juan P. Garrahan"; ArgentinaFil: Papp Wallace, Krisztina M.. Case Western Reserve University; Estados UnidosFil: Bonomo, Robert A.. Case Western Reserve University; Estados UnidosFil: Vazquez, Miryam S.. Gobierno de la Ciudad de Buenos Aires. Hospital General de Niños "Ricardo Gutiérrez"; ArgentinaFil: Power, Pablo. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Departamento de Microbiología, Inmunología y Biotecnología. Cátedra de Microbiología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay; ArgentinaFil: Ramirez, María S.. University Fullerton; Estados Unido
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