Beyond Resistance and Resilience: The Altered Book in Adolescent and Young Adult Complex Trauma Recovery, a Method

The method detailed in this paper was developed to explore the potential positive impacts altered bookmaking could have on adolescents and young adults with complex trauma histories. The paper describes the literature supporting the use of art therapy in trauma treatment and using altered books with adolescents to explore identity and assist in treating depression and anxiety. Trauma is typically not communicated linearly or with words; art therapy is effective in treating individuals with trauma, as the modality allows the client to communicate symbolically. By externalizing the story onto an object, a book, clients create space from their thoughts, memories, and emotions. To expand upon these findings, I created trauma-informed interventions for adolescents and young adults with complex trauma histories to explore the potential value of an altered book art therapy intervention with this population. My observations of the clients’ positive responses have supported the need for future research of providing an altered book intervention to assist in the progression through trauma recovery

A study of the Dissolution of UK Nuclear Waste Glass in Cement Waters

Within the United Kingdom (UK), it is proposed that nuclear waste will be disposed of in a geological facility, utilising an engineered barrier system that will be optimised to physically and chemically impede the transport of radionuclides to the biosphere. Understanding glass dissolution in environmental conditions designed to mimic geological disposal is paramount to the safety case of the UK’s radioactive waste disposal programme. Interaction of groundwater with the cementitious components of the facility will lead to the presence of high pH conditions within a disposal facility. The effect of such cement leachates on the durability of vitrified wasteforms is not well understood. The following body of work aims to address the concerns of nuclear waste glass in contact with cementitious materials. Here we present results from glass durability studies using simulated cement leachates and equilibrated cement water to elucidate the mechanisms that govern glass corrosion under these complex geochemical conditions. The normalised mass loss and normalised leaching rate as a function of cement leachate composition was determined by effluent solution analysis. Additionally, we present characterisation results collected on alteration layers by conducting x-ray diffraction and electron microscopy measurements on glass powders and monolith samples. Collectively, these data provide new insights into the mechanisms that govern glass dissolution in the complex geochemical conditions expected for vitrified UK waste if water breaches the engineered barrier system in a geological disposal facility. The work demonstrated in this thesis indicates that glass dissolution is less severe in cementitious leachates compared to pure water and young synthetic cement waters are more corrosive than evolved solutions with a lower concentration of alkali/alkaline earth ions

Seal whiskers vibrate over broad frequencies during hydrodynamic tracking

© The Author(s), 2017. This article is distributed under the terms of the Creative Commons Attribution License. The definitive version was published in Scientific Reports 7 (2017): 8350, doi:10.1038/s41598-017-07676-w.Although it is known that seals can use their whiskers (vibrissae) to extract relevant information from complex underwater flow fields, the underlying functioning of the system and the signals received by the sensors are poorly understood. Here we show that the vibrations of seal whiskers may provide information about hydrodynamic events and enable the sophisticated wake-tracking abilities of these animals. We developed a miniature accelerometer tag to study seal whisker movement in situ. We tested the ability of the tag to measure vibration in excised whiskers in a flume in response to laminar flow and disturbed flow. We then trained a seal to wear the tag and follow an underwater hydrodynamic trail to measure the whisker signals available to the seal. The results showed that whiskers vibrated at frequencies of 100–300 Hz, with a dynamic response. These measurements are the first to capture the incoming signals received by the vibrissae of a live seal and show that there are prominent signals at frequencies where the seal tactogram shows good sensitivity. Tapping into the mechanoreceptive interface between the animal and the environment may help to decipher the functional basis of this extraordinary hydrodynamic detection ability.Funding was provided by the NSF GRFP and NISE section 219 to C. Murphy and by the Office of Naval Research (N000141910468) to B. Calhoun

Differential respiratory health effects from the 2008 northern California wildfires: A spatiotemporal approach

AbstractWe investigated health effects associated with fine particulate matter during a long-lived, large wildfire complex in northern California in the summer of 2008. We estimated exposure to PM2.5 for each day using an exposure prediction model created through data-adaptive machine learning methods from a large set of spatiotemporal data sets. We then used Poisson generalized estimating equations to calculate the effect of exposure to 24-hour average PM2.5 on cardiovascular and respiratory hospitalizations and ED visits. We further assessed effect modification by sex, age, and area-level socioeconomic status (SES). We observed a linear increase in risk for asthma hospitalizations (RR=1.07, 95% CI=(1.05, 1.10) per 5µg/m3 increase) and asthma ED visits (RR=1.06, 95% CI=(1.05, 1.07) per 5µg/m3 increase) with increasing PM2.5 during the wildfires. ED visits for chronic obstructive pulmonary disease (COPD) were associated with PM2.5 during the fires (RR=1.02 (95% CI=(1.01, 1.04) per 5µg/m3 increase) and this effect was significantly different from that found before the fires but not after. We did not find consistent effects of wildfire smoke on other health outcomes. The effect of PM2.5 during the wildfire period was more pronounced in women compared to men and in adults, ages 20–64, compared to children and adults 65 or older. We also found some effect modification by area-level median income for respiratory ED visits during the wildfires, with the highest effects observed in the ZIP codes with the lowest median income. Using a novel spatiotemporal exposure model, we found some evidence of differential susceptibility to exposure to wildfire smoke

Senior Recital, Colleen Trempe, trombone

The presentation of this senior recital will fulfill in part the requirements for a Bachelor of Music degree in Jazz Studies. Colleen Trempe studies trombone with Antonio J. Garcia

Short communication : the dissolution of UK simulant vitrified high-level-waste in groundwater solutions

Dissolution of a simulant UK nuclear waste glass containing Mg, Ca and Zn was investigated over 35 d at 50 °C in water and simulant groundwater solutions. The dissolution rates were influenced subtly by the groundwater composition, following the trend, from least to most durable: clay > water > granite ≈ saline. Solutions were rapidly silica saturated but boron dissolution rates continued to increase. This is hypothesised to be due to the formation of secondary Mg-silicate precipitates, preventing the formation of a passivating silica gel layer and allowing glass dissolution to proceed at close to the maximum rate

VCU Jazz Orchestra I

First half of performanc

Evaluation of a Heat Vulnerability Index on Abnormally Hot Days: An Environmental Public Health Tracking Study

Background: Extreme hot weather conditions have been associated with increased morbidity and mortality, but risks are not evenly distributed throughout the population. Previously, a heat vulnerability index (HVI) was created to geographically locate populations with increased vulnerability to heat in metropolitan areas throughout the United States

Benchtop Zone Refinement of Simulated Future Spent Nuclear Fuel Pyroprocessing Waste.

The UK’s adoption of pyroprocessing of spent nuclear fuel as an alternative to the current aqueous processing routes requires a robust scientific underpinning of all relevant processes. One key process is the clean-up of the contaminated salt from the electroreducing and electrorefining processes. A proposed method for this clean-up is zone refining, whereby the tendency of the contaminants to remain in the liquid phase during melting and freezing is exploited to ‘sweep’ the contaminants to one end of the sample. Experiments were performed, utilising off-the-shelf laboratory equipment, to demonstrate the feasibility of zone refining for clean-up of electroreducing and electrorefining wastes. This was successful for the electrorefining simulant samples, with effective segregation coefficient, keff, values, which provide a measure of the degree of separation in the sample, between 0 and 1. Lower values indicate greater separation, with values of as low as 0.542 achieved here, corresponding to a reduction in RECl3 content from 10.0 wt. % to 8.4 wt. % (for 80% salt reuse). Due to difficulties in obtaining a fully homogeneous electroreducing simulant waste, it was not possible to demonstrate the feasibility of zone refining using the current experimental setup. Further research is required to elucidate the correct preparation conditions for production of homogeneous electroreducing waste simulants

Pan-Cancer Analysis of lncRNA Regulation Supports Their Targeting of Cancer Genes in Each Tumor Context

Long noncoding RNAs (lncRNAs) are commonly dys-regulated in tumors, but only a handful are known toplay pathophysiological roles in cancer. We inferredlncRNAs that dysregulate cancer pathways, onco-genes, and tumor suppressors (cancer genes) bymodeling their effects on the activity of transcriptionfactors, RNA-binding proteins, and microRNAs in5,185 TCGA tumors and 1,019 ENCODE assays.Our predictions included hundreds of candidateonco- and tumor-suppressor lncRNAs (cancerlncRNAs) whose somatic alterations account for thedysregulation of dozens of cancer genes and path-ways in each of 14 tumor contexts. To demonstrateproof of concept, we showed that perturbations tar-geting OIP5-AS1 (an inferred tumor suppressor) andTUG1 and WT1-AS (inferred onco-lncRNAs) dysre-gulated cancer genes and altered proliferation ofbreast and gynecologic cancer cells. Our analysis in-dicates that, although most lncRNAs are dysregu-lated in a tumor-specific manner, some, includingOIP5-AS1, TUG1, NEAT1, MEG3, and TSIX, synergis-tically dysregulate cancer pathways in multiple tumorcontexts