Discovery of a Wolf-Rayet Star Through Detection of its Photometric Variability

We report the serendipitous discovery of a heavily reddened Wolf-Rayet star that we name WR142b. While photometrically monitoring a cataclysmic variable, we detected weak variability in a nearby field star. Low-resolution spectroscopy revealed a strong emission line at 7100 Ang., suggesting an unusual object and prompting further study. A spectrum taken with the Hobby-Eberly Telescope confirms strong HeII emission and a NIV 7112 Ang. line consistent with a nitrogen-rich Wolf-Rayet star of spectral class WN6. Analysis of the HeII line strengths reveals no detectable hydrogen in WR142b. A blue-sensitive spectrum obtained with the Large Binocular Telescope shows no evidence for a hot companion star. The continuum shape and emission line ratios imply a reddening of E(B-V)=2.2 to 2.5 mag. If not for the dust extinction, this new Wolf-Rayet star could be visible to the naked eye.Comment: 15 pages, 6 figures, submitted to the Astronomical Journa

Liver ‘organ on a chip’

© 2017 The liver plays critical roles in both homeostasis and pathology. It is the major site of drug metabolism in the body and, as such, a common target for drug-induced toxicity and is susceptible to a wide range of diseases. In contrast to other solid organs, the liver possesses the unique ability to regenerate. The physiological importance and plasticity of this organ make it a crucial system of study to better understand human physiology, disease, and response to exogenous compounds. These aspects have impelled many to develop liver tissue systems for study in isolation outside the body. Herein, we discuss these biologically engineered organoids and microphysiological systems. Keywords: Microphysiologic systems; Organoids; 3D culture systemsNational Institutes of Health (U.S.) (Grant UH3TR000496)National Institutes of Health (U.S.) (Grant UH3TR000503

Next Generation Life Support Project Status

Next Generation Life Support (NGLS) is one of several technology development projects sponsored by NASA s Game Changing Development Program. The NGLS Project is developing life support technologies (including water recovery and space suit life support technologies) needed for humans to live and work productively in space. NGLS has three project tasks: Variable Oxygen Regulator (VOR), Rapid Cycle Amine (RCA) swing bed, and Alternative Water Processor (AWP). The RCA swing bed and VOR tasks are directed at key technology needs for the Portable Life Support System (PLSS) for an Advanced Extravehicular Mobility Unit, with focus on test article development and integrated testing in an Advanced PLSS in cooperation with the Advanced Extra Vehicular Activity (EVA) Project. An RCA swing-bed provides integrated carbon dioxide removal and humidity control that can be regenerated in real time during an EVA. The VOR technology will significantly increase the number of pressure settings available to the space suit. Current space suit pressure regulators are limited to only two settings whereas the adjustability of the advanced regulator will be nearly continuous. The AWP effort, based on natural biological processes and membrane-based secondary treatment, will result in the development of a system capable of recycling wastewater from sources expected in future exploration missions, including hygiene and laundry water. This paper will provide a status of technology development activities and future plans

Systematic nomenclature for the PLUNC/PSP/BSP30/SMGB proteins as a subfamily of the BPI fold-containing superfamily

We present the BPIFAn/BPIFBn systematic nomenclature for the PLUNC (palate lung and nasal epithelium clone)/PSP (parotid secretory protein)/BSP30 (bovine salivary protein 30)/SMGB (submandibular gland protein B) family of proteins, based on an adaptation of the SPLUNCn (short PLUNCn)/LPLUNCn (large PLUNCn) nomenclature. The nomenclature is applied to a set of 102 sequences which we believe represent the current reliable data for BPIFA/BPIFB proteins across all species, including marsupials and birds. The nomenclature will be implemented by the HGNC (HUGO Gene Nomenclature Committee)

High-frequency ultrasonic speckle velocimetry in sheared complex fluids

High-frequency ultrasonic pulses at 36 MHz are used to measure velocity profiles in a complex fluid sheared in the Couette geometry. Our technique is based on time-domain cross-correlation of ultrasonic speckle signals backscattered by the moving medium. Post-processing of acoustic data allows us to record a velocity profile in 0.02--2 s with a spatial resolution of 40 $\mu$m over 1 mm. After a careful calibration using a Newtonian suspension, the technique is applied to a sheared lyotropic lamellar phase seeded with polystyrene spheres of diameter 3--10 $\mu$m. Time-averaged velocity profiles reveal the existence of inhomogeneous flows, with both wall slip and shear bands, in the vicinity of a shear-induced ``layering'' transition. Slow transient regimes and/or temporal fluctuations can also be resolved and exhibit complex spatio-temporal flow behaviors with sometimes more than two shear bands.Comment: 15 pages, 18 figures, submitted to Eur. Phys. J. A

Animators of Atlanta: Layering Authenticity in the Creative Industries

This dissertation explores post-authentic neoliberal animation production culture, tracing the ways authenticity is used as a resource to garner professional autonomy and security during precarious times. Animators engage in two modes of production, the first in creating animated content, and the other in constructing a professional identity. Analyzing animator discourse allows for a nuanced exploration of how these processes interact and congeal into common sense. The use of digital software impacts the animator’s capacity to legitimize themselves as creatives and experts, traditional tools become vital for signifying creative authenticity in a professional environment. The practice of decorating one’s desk functions as a tactic to layer creative authenticity, but the meaning of this ritual is changing now that studios shift to open spaces while many animators work from home. Layering authenticity on-screen often requires blending techniques from classical Hollywood cinema into animated performance, concomitant with a bid to legitimate the role of the authentic interlocutor for the character. Increasingly animators feel pressure to layer authenticity online, establishing an audience as a means to hedge against precarity. The recombined self must balance the many methods for layering creative and professional authenticity with the constraints and affordances of their tools, along with the demands of the studio, to yield cultural capital vital for an animator’s survival in an industry defined at once by its limitless expressive potential and economic uncertainty