PHYSICAL ACTIVITY LEVELS, MOTOR PERFORMANCE AND RELATED FACTORS IN ADOLESCENCE. THE UNIVERSITY OF FOGGIA REGIONAL OBSERVATORY IN ITALY

Physical activities promotion in developmental age is a public health priority and numerous studies highlight the benefits of various structured and unstructured activities for the prevention of non-communicable diseases and health promotion. Curricular physical education in secondary school offers several and different opportunities to practice physical activities that help promoting learning competences, complying with international guidelines on physical activity and acquiring correct lifestyles. Increasing levels of daily physical activity as well as the development of motor skills are a specific curricular area necessary to structure the conditions for motor learning and the premises for the continuation of sports and physical activities in extracurricular hours. Unfortunately, environmental and socio-cultural characteristics in Italy contribute to increase sedentary habits, limit opportunities to practice unstructured physical activities and lead to a reduction in motor performance. The aim of the following paper is to present the project of the University of Foggia in Italy aimed at systematic monitoring the adolescents’ levels of physical activity and motor development. The Regional Observatory at the University of Foggia wants to assess motor skills related to health, analyze correlations with body weight and gender differences, compare the results of prevention interventions carried out in school and structure the premises for regional health promotion projects

Negative correlation between BMI and perception of physical activity in adolescents

The development of obesity is a complex problem, conditioned by heterogeneous factors. Despite the impressive amount of research, the phenomenon is difficult to investigate, due to the inadequacy of quantitative methods to assess the negative spiral that triggers between self-efficacy perception and physical activity levels. The present study uses tools from quantitative research relating to conditional motor skills and tools coming from qualitative research relating to psychological factors. The hypothesis is that overweight affects not only motor performance, but also related psychological factors (perceived self-efficacy and enjoyment). The survey was conducted on a group of 177 adolescents (85 males and 92 females) aged between 14 and 18 years in the Puglia region. The subjects, once the quantitative tests were carried out, completed the PAQ_C scales (levels of physical activity in the last week), PACES (Physical Activity Enjoyment Scale) and Motor Self-efficacy questionnaire. Attested a negative relationship between overweight and motor tests results, a Spearman ranks correlation analysis was carried out to investigate the BMI relationship with the scores obtained at the qualitative scales. A negative correlation was identified between BMI and the scores of scales for all subjects (rs = -0.03; -0.15; -0.09 for PAQ_C, PACES and SEM). Based on the analysis of the collected data, adolescents with a high BMI have a high probability of developing adverse perceptions of their effectiveness and facing a high risk of sedentary behaviours

Development and Implementation of the AIDA International Registry for Patients with Non-Infectious Scleritis

Introduction This article points out the design, methods, development and deployment of the international registry promoted by the AutoInflammatory Disease Alliance (AIDA) Network with the aim to define and assess paediatric and adult patients with immune-mediated scleritis. Methods This registry collects both retrospective and prospective real-world data from patients with non-infectious scleritis through the Research Electronic Data Capture (REDCap) tool and aims to promote knowledge and real-life evidence from patients enrolled worldwide; the registry also allows the collection of standardised data, ensuring the highest levels of security and anonymity of patients' data and flexibility to change according to scientific acquisitions over time. The communication with other similar registries has been also ensured in order to pursue the sustainability of the project with respect to the adaptation of collected data to the most diverse research projects. Results Since the launch of the registry, 99 centres have been involved from 20 countries and four continents. Forty-eight of the centres have already obtained a formal approval from their local ethics committees. At present, the platform counts 259 users (95 principal investigators, 160 site investigators, 2 lead investigators, and 2 data managers); the platform collects baseline and follow-up data using 3683 fields organised into 13 instruments, including patient's demographics, history, symptoms, trigger or risk factors, therapies and healthcare utilization. Conclusions The development of the AIDA International Registry for patients with non-infectious scleritis will allow solid research on this rare condition. Real-world evidence resulting from standardised real-life data will lead to the optimisation of routine clinical and therapeutic management, which are currently limited by the rarity of this ocular inflammatory condition

Development and implementation of the AIDA International Registry for patients with Periodic Fever, Aphthous stomatitis, Pharyngitis, and cervical Adenitis syndrome

Objective: Aim of this paper is to illustrate the methodology, design, and development of the AutoInflammatory Disease Alliance (AIDA) International Registry dedicated to patients with the Periodic Fever, Aphthous stomatitis, Pharyngitis, and cervical Adenitis (PFAPA) syndrome. Methods: This is a physician-driven, non-population- and electronic-based registry proposed to gather real-world demographics, clinical, laboratory, instrumental and socioeconomic data from PFAPA patients. Data recruitment is realized through the on-line Research Electronic Data Capture (REDCap) tool. This registry is thought to collect standardized information for clinical research leading to solid real-life evidence. The international scope and the flexibility of the registry will facilitate the realization of cutting-edge study projects through the constant updating of variables and the possible merging and transfer of data between current and future PFAPA registries. Results: A total of 112 centers have already been involved from 23 countries and 4 continents starting from August 24th, 2021, to April 6th, 2022. In total 56/112 have already obtained the formal approval from their local Ethics Committees. The platform counts 321 users (113 principal investigators, 203 site investigators, two lead investigators, and three data managers). The registry collects retrospective and prospective data using 3,856 fields organized into 25 instruments, including PFAPA patient's demographics, medical histories, symptoms, triggers/risk factors, therapies, and impact on the healthcare systems. Conclusions: The development of the AIDA International Registry for PFAPA patients will enable the on-line collection of standardized data prompting real-life studies through the connection of worldwide groups of physicians and researchers. This project can be found on NCT 05200715

Development and Implementation of the AIDA International Registry for Patients With Undifferentiated Systemic AutoInflammatory Diseases

Objective: This paper points out the design, development and deployment of the AutoInflammatory Disease Alliance (AIDA) International Registry dedicated to pediatric and adult patients affected by Undifferentiated Systemic AutoInflammatory Diseases (USAIDs). Methods: This is an electronic registry employed for real-world data collection about demographics, clinical, laboratory, instrumental and socioeconomic data of USAIDs patients. Data recruitment, based on the Research Electronic Data Capture (REDCap) tool, is designed to obtain standardized information for real-life research. The instrument is endowed with flexibility, and it could change over time according to the scientific acquisitions and potentially communicate with other similar tools; this platform ensures security, data quality and data governance. Results: The focus of the AIDA project is connecting physicians and researchers from all over the world to shed a new light on heterogeneous rare diseases. Since its birth, 110 centers from 23 countries and 4 continents have joined the AIDA project. Fifty-four centers have already obtained the approval from their local Ethics Committees. Currently, the platform counts 290 users (111 Principal Investigators, 179 Site Investigators, 2 Lead Investigators, and 2 data managers). The Registry is collecting baseline and follow-up data using 3,769 fields organized into 23 instruments, which include demographics, history, symptoms, trigger/risk factors, therapies, and healthcare information access for USAIDs patients. Conclusions: The development of the AIDA International Registry for USAIDs patients will facilitate the online collection of real standardized data, connecting a worldwide group of researchers: the Registry constitutes an international multicentre observational groundwork aimed at increasing the patient cohort of USAIDs in order to improve our knowledge of this peculiar cluster of autoinflammatory diseases