Conference on Binary Optics: An Opportunity for Technical Exchange

The papers herein were presented at the Conference on Binary Optics held in Huntsville, AL, February 23-25, 1993. The papers were presented according to subject as follows: modeling and design, fabrication, and applications. Invited papers and tutorial viewgraphs presented on these subjects are included

Real-time flood inundation forecasting and mapping for key railway infrastructure: a UK case study

Flooding events that impede railway infrastructure can cause severe travel delays for the general public and large fines in delayed minutes for the rail industry. Early warnings of flood inundation can give more time to implement mitigation measures which help reduce cancellations, delays and fines. Initial work is reported on the development of a real-time flood inundation forecasting and mapping system for the Cowley Bridge track area near Exeter, UK. This location is on one of the main access routes to South West England and has suffered major floods in the past resulting in significant transport impacts. Flood forecasting systems in the UK mainly forecast river level/flow rather than extent and depth of flood inundation. Here, the development of a chain of coupled models is discussed that link rainfall to river flow, river level and flood extent for the rail track area relating to Cowley Bridge. Historical events are identified to test model performance in predicting inundation of railway infrastructure. The modelling system will operate alongside a series of in-situ sensors chosen to enhance the flood mapping forecasting system. Sensor data will support offline model calibration/verification and real-time data assimilation as well as monitoring flood conditions to inform track closure decisions

Biological methods to assess unaccompanied asylum-seeking children's age

Report by the interim Age Estimation Science Advisory Committee (AESAC) on scientific methodologies for assessing the age of unaccompanied asylum-seeking children

Biological methods to assess unaccompanied asylum-seeking children's age

Report by the interim Age Estimation Science Advisory Committee (AESAC) on scientific methodologies for assessing the age of unaccompanied asylum-seeking children

Biological methods to assess unaccompanied asylum-seeking children’s age:Interim Age Estimation Science Advisory Committee

Report by the interim Age Estimation Science Advisory Committee (AESAC) on scientific methodologies for assessing the age of unaccompanied asylum-seeking children.<br/

Biological methods to assess unaccompanied asylum-seeking children’s age:Interim Age Estimation Science Advisory Committee

Report by the interim Age Estimation Science Advisory Committee (AESAC) on scientific methodologies for assessing the age of unaccompanied asylum-seeking children.<br/

New universal ITS2 primers for high-resolution herbivory analyses using DNA metabarcoding in both tropical and temperate zones

DNA metabarcoding is a rapidly growing technique for obtaining detailed dietary information. Current metabarcoding methods for herbivory, using a single locus, can lack taxonomic resolution for some applications. We present novel primers for the second internal transcribed spacer of nuclear ribosomal DNA (ITS2) designed for dietary studies in Mauritius and the UK, which have the potential to give unrivalled taxonomic coverage and resolution from a short-amplicon barcode. In silico testing used three databases of plant ITS2 sequences from UK and Mauritian floras (native and introduced) totalling 6561 sequences from 1790 species across 174 families. Our primers were well-matched in silico to 88% of species, providing taxonomic resolution of 86.1%, 99.4% and 99.9% at the species, genus and family levels, respectively. In vitro, the primers amplified 99% of Mauritian (n = 169) and 100% of UK (n = 33) species, and co-amplified multiple plant species from degraded faecal DNA from reptiles and birds in two case studies. For the ITS2 region, we advocate taxonomic assignment based on best sequence match instead of a clustering approach. With short amplicons of 187–387 bp, these primers are suitable for metabarcoding plant DNA from faecal samples, across a broad geographic range, whilst delivering unparalleled taxonomic resolution

Urban green grabbing : Residential real estate developers discourse and practice in gentrifying Global North neighborhoods

Altres ajuts: Acord transformatiu CRUE-CSICUnidad de excelencia María de Maeztu CEX2019-000940-MIn the movement towards building greener and more sustainable cities, real estate developers are increasingly embracing not only green building construction but broader strategies and action related to urban greening. To date, their motivations and role in this broader urban greening dynamic remains underexplored, yet essential to dissect how greening is sustained and real estate development legitimized in revitalizing neighborhoods. With an eye to better understand green urban capitalist development processes underway amidst financialized nature and urban growth, and the equity impacts they entail, we explore residential real estate developers urban greening discourses and practices. Through a novel dataset of 42 interviews with private and non-profit residential real estate developers in 15 mid-sized American, Western European and Canadian cities, we uncover three differentiated but interconnected discourses around (i) financial benefits, (ii) consumer- or investor-driven demand and (iii) social dimensions behind developers' interest in urban greening. We argue that developers embark on urban green grabbing through "green" discursive and material value appropriation and rent extraction strategies. Urban green grabbing is conceptually useful in depicting who benefits and how/when developers extract additional rent, surplus value, social capital and/or prestige from locating new residential projects adjacent to new or up-and-coming green amenities. Our work contributes to debates about urban greening's perceived position as a value-producing and rent-extracting good from both a political economy and political ecology perspectiv

What’s left in the cupboard? Older antimicrobials for treating gonorrhoea

Background: Neisseria gonorrhoeae has developed resistance to all antimicrobials used to treat gonorrhoea, with even ceftriaxone being undermined. It is therefore important to examine any potential to redeploy older antimicrobials routinely used for other infections to treat ceftriaxone-resistant gonococcal infections. Objectives: We examined the susceptibility of N. gonorrhoeae to aztreonam, chloramphenicol, co-trimoxazole, fosfomycin, piperacillin/tazobactam and rifampicin. Methods: N. gonorrhoeae isolates (n = 94) were selected to include a range of antimicrobial susceptibilities: 58 were collected in the Gonococcal Resistance to Antimicrobials Surveillance Programme; 17 were clinical isolates referred to the PHE reference laboratory; and 19 were control strains. MICs were determined by agar dilution for the six study antimicrobials and for ceftriaxone and azithromycin as comparators. Results: There was correlation between piperacillin/tazobactam and ceftriaxone MICs, but all five isolates with high ceftriaxone MICs (>0.5 mg/L) were inhibited by piperacillin/tazobactam at 0.06–0.5 mg/L. Aztreonam MICs for ceftriaxone-resistant isolates exceeded those of ceftriaxone. Among non-β-lactams, fosfomycin and co-trimoxazole had low, tightly clustered MICs, suggesting widespread susceptibility, rifampicin split the collection into highly susceptible and highly resistant groups and chloramphenicol had a wide MIC distribution. Conclusions: Although unsuitable for empirical use, piperacillin/tazobactam, fosfomycin, co-trimoxazole, rifampicin and, possibly, chloramphenicol could be considered for individual patients with ceftriaxone-resistant gonococcal infection once MICs are known. Wider surveillance of the susceptibility of N. gonorrhoeae to these agents is needed, along with clinical trials and the establishment of clinical breakpoints for N gonorrhoeae