219 research outputs found
Flavor Changing Processes in Supersymmetric Models with Hybrid Gauge- and Gravity-Mediation
We consider supersymmetric models where gauge mediation provides the dominant
contributions to the soft supersymmetry breaking terms while gravity mediation
provides sub-dominant yet non-negligible contributions. We further assume that
the gravity-mediated contributions are subject to selection rules that follow
from a Froggatt-Nielsen symmetry. This class of models constitutes an example
of viable and natural non-minimally flavor violating models. The constraints
from mixing in the neutral K system imply that the modifications to the
Standard Model predictions for mixing in the neutral B_d and B_s systems are
generically at most at the percent level, but can be of order ten percent for
large . The modifications for the neutral D system mixing are
generically at most of order a few percent, but in a special subclass of models
they can be of order one. We point out processes relevant for
flavor violation in hybrid mediation.Comment: 30 pages, 3 figure
Constraining New Physics with the CDF Measurement of CP Violation in
Recently, the CDF collaboration has reported a measurement of the CP
asymmetry in the decay: . We
analyze the constraints that follow from this measurement on the size and the
phase of contributions from new physics to B-\barB mixing. Defining the
relative phase between the full amplitude and the Standard Model
contribution to be , we find a new bound: \sin2\theta_d\gsim-0.6
(-0.87) at one sigma (95% CL). Further implications for the CP asymmetry in
semileptonic B decays are discussed.Comment: 13 pages, harvmac, 3 figures; v2: a discussion of new physics effects
on tree level decays added; references added; accepted for publication in
Physical Review Letter
Final State Interactions and New Physics in B -> pi K Decays
Within the Standard Model, and if one assumes that soft rescattering effects
are negligible, the CP asymmetry A^dir_CP (B^\pm -> \pi^\pm K) is predicted to
be very small and the ratio R = BR(B_d -> \pi^\mp K^\pm)/BR(B^\pm -> \pi^\pm K)
provides a bound on the angle \gamma of the unitarity triangle, sin^2 \gamma
\leq R. We estimate the corrections from soft rescattering effects using an
approach based on Regge phenomenology, and find effects of order 10% with large
uncertainties. In particular, we conclude that A^dir_CP \sim 0.2 and sin^2
\gamma \sim 1.2 R could not be taken unambiguously to signal New Physics. Using
SU(3) relations, we suggest experimental tests that could constrain the size of
the soft rescattering effects thus reducing the related uncertainty. Finally,
we study the effect of various models of New Physics on A^dir_CP and on R.Comment: 20 pages, RevTex, no figures; a few typos corrected, references
added, brief additional discussion of uncertanties is adde
Human induced pluripotent stem cell models of neurodegenerative disorders for studying the biomedical implications of autophagy
A Unique Human-Fox Burial from a Pre-Natufian Cemetery in the Levant (Jordan)
New human burials from northern Jordan provide important insights into the appearance of cemeteries and the nature of human-animal relationships within mortuary contexts during the Epipalaeolithic period (c. 23,000â11,600 cal BP) in the Levant, reinforcing a socio-ideological relationship that goes beyond predator-prey. Previous work suggests that archaeological features indicative of social complexity occur suddenly during the latest Epipalaeolithic phase, the Natufian (c. 14,500â11,600 cal BP). These features include sedentism, cemeteries, architecture, food production, including animal domestication, and burials with elaborate mortuary treatments. Our findings from the pre-Natufian (Middle Epipalaeolithic) cemetery of âUyun al-Hammam demonstrate that joint human-animal mortuary practices appear earlier in the Epipalaeolithic. We describe the earliest human-fox burial in the Near East, where the remains of dogs have been found associated with human burials at a number of Natufian sites. This is the first time that a fox has been documented in association with human interments pre-dating the Natufian and with a particular suite of grave goods. Analysis of the human and animal bones and their associated artefacts provides critical data on the nature and timing of these newly-developing relationships between people and animals prior to the appearance of domesticated dogs in the Natufian
Recovery Rates of Diagnostic Cardiac Procedural Volume in Oceania 1 Year Into COVID-19: The IAEA Non-Invasive Cardiology Protocol Survey on COVID-19 (INCAPS COVID 2)
AimThe aim of this study was to assess the recovery rates of diagnostic cardiac procedure volumes in the Oceania Region, midway through the coronavirus disease 2019 (COVID-19) pandemic.MethodsA survey was performed comparing procedure volumes between March 2019 (pre-pandemic), April 2020 (during first wave of COVID-19 pandemic), and April 2021 (1 year into the COVID-19 pandemic). A total of 31 health care facilities within Oceania that perform cardiac diagnostic procedures were surveyed, including a mixture of metropolitan and regional, hospital and outpatient, public and private sites, as well as teaching and non-teaching hospitals. A comparison was made with 549 centres in 96 countries in the rest of the world (RoW) outside of Oceania. The total number and median percentage change in procedure volume were measured between the three timepoints, compared by test type and by facility.ResultsA total of 11,902 cardiac diagnostic procedures were performed in Oceania in April 2021 as compared with 11,835 pre-pandemic in March 2019 and 5,986 in April 2020; whereas, in the RoW, 499,079 procedures were performed in April 2021 compared with 497,615 pre-pandemic in March 2019 and 179,014 in April 2020. There was no significant difference in the median recovery rates for total procedure volumes between Oceania (â6%) and the RoW (â3%) (p=0.81). While there was no statistically significant difference in percentage recovery been functional ischaemia testing and anatomical coronary testing in Oceania as compared with the RoW, there was, however, a suggestion of poorer recovery in anatomical coronary testing in Oceania as compared with the RoW (CT coronary angiography -16% in Oceania vs â1% in RoW, and invasive coronary angiography â20% in Oceania vs â9% in RoW). There was no statistically significant difference in recovery rates in procedure volume between metropolitan vs regional (p=0.44), public vs private (p=0.92), hospital vs outpatient (p=0.79), or teaching vs non-teaching centres (p=0.73).ConclusionsTotal cardiology procedure volumes in Oceania normalised 1 year post-pandemic compared to pre-pandemic levels, with no significant difference compared with the RoW and between the different types of health care facilities.â<br/
Early Bronze Age copper production systems in the northern Arabah Valley: New insights from archaeomagnetic study of slag deposits in Jordan and Israel
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Snowball Earth climate dynamics and Cryogenian geology-geobiology
Geological evidence indicates that grounded ice sheets reached sea level at all latitudes during two long-lived Cryogenian (58 and â„5 My) glaciations. Combined uranium-lead and rhenium-osmium dating suggests that the older (Sturtian) glacial onset and both terminations were globally synchronous. Geochemical data imply that CO2 was 102 PAL (present atmospheric level) at the younger termination, consistent with a global ice cover. Sturtian glaciation followed breakup of a tropical supercontinent, and its onset coincided with the equatorial emplacement of a large igneous province. Modeling shows that the small thermal inertia of a globally frozen surface reverses the annual mean tropical atmospheric circulation, producing an equatorial desert and net snow and frost accumulation elsewhere. Oceanic ice thickens, forming a sea glacier that flows gravitationally toward the equator, sustained by the hydrologic cycle and by basal freezing and melting. Tropical ice sheets flow faster as CO2 rises but lose mass and become sensitive to orbital changes. Equatorial dust accumulation engenders supraglacial oligotrophic meltwater ecosystems, favorable for cyanobacteria and certain eukaryotes. Meltwater flushing through cracks enables organic burial and submarine deposition of airborne volcanic ash. The subglacial ocean is turbulent and well mixed, in response to geothermal heating and heat loss through the ice cover, increasing with latitude. Terminal carbonate deposits, unique to Cryogenian glaciations, are products of intense weathering and ocean stratification. Whole-ocean warming and collapsing peripheral bulges allow marine coastal flooding to continue long after ice-sheet disappearance. The evolutionary legacy of Snowball Earth is perceptible in fossils and living organisms
âOthers-in-Lawâ: Legalism in the Economy of Religious Differences
Religious legalism encompasses a wide range of attitudes that assign religious meaning to legal content or to legal compliance. The phenomenology of religious legalism is assuming a significant role in various contemporary debates about legal pluralism, accommodation of religious minorities, religious freedom, and so forth. This article revises this conception and the commonplace equation of Judaism and legalism. It suggests that we ought to regard both as part of the economy of religious differences by which religious identities are expressed and defined as alternatives. The common ascription of religious legalism to Judaism (and Islam) is criticized here through a historical analysis of the law-religion-identity matrix in three cultural settings: late ancient Judeo-Hellenic, medieval JudeoâArabic, and post-Reformation Europe
Worldwide Disparities in Recovery of Cardiac Testing 1 Year Into COVID-19
FUNDING SUPPORT AND AUTHOR DISCLOSURES Dr Williams is supported by the British Heart Foundation (FS/ICRF/ 20/26002). Dr Einstein has received speaker fees from Ionetix; has received consulting fees from W. L. Gore & Associates; has received authorship fees from Wolters Kluwer Healthcare â UpToDate; and has received grants or grants pending to his institution from Attralus, Canon Medical Systems, Eidos Therapeutics, GE Healthcare, Pfizer, Roche Medical Systems, W. L. Gore & Associates, and XyloCor Ther- apeutics. Dr Williams has received speaker fees from Canon Medical Systems. Dr Dorbala has received honoraria from Pfizer and GE Healthcare; and has received grants to her institution from Pfizer and GE Healthcare. Dr Sinitsyn has received congress speaker honoraria from Bayer, GE Healthcare, Siemens, and Philips. Dr Kudo has received research grants from Nihon Medi-physics and FUJIFILM Toyama Chemical. Dr Bucciarelli-Ducci is CEO (part-time) of the So- ciety for Cardiovascular Magnetic Resonance; and has received speaker fees from Circle Cardiovascular Imaging, Bayer, and Siemens Healthineers. All other authors have reported that they have no re- lationships relevant to the contents of this paper to disclose.Peer reviewedPublisher PD
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