Estudo Comparativo entre Laboratórios Remotos e Simuladores

Os laboratórios remotos são ferramentas ágeis e acessíveis, proporcionando maior acesso aos alunos através do conceito de Educação 4.0. O uso destes laboratórios sugere o desenvolvimento da capacidade analítica dos usuários, apresentando resultados reais com influências externas como térmica, elétrica, magnética ou eletromagnética e ainda as não idealidades relacionadas aos aspectos construtivos de componentes eletrônicos. Assim, este capítulo propõe explorar o potencial dos laboratórios remotos realizando experimentações práticas reais no laboratório remoto VISIR em comparação a simulações no PSIM e PROTEUS, verificando as diferenças entre as plataformas.Remote laboratories are agile and accessible tools, providing major access to the students through the concept of Education 4.0. These laboratories support the development of the users’ analytical capacity, showing real results with external influences like thermal, electrical, magnetic or electromagnetic and the non-idealities related to the electronics components constructive aspects. In this context, this chapter explores the remote laboratories potential using real experiments on VISIR in comparison with simulations on PSIM and PROTEUS, looking for the differences between these two educational platforms.info:eu-repo/semantics/publishedVersio

Acute ischemic preconditioning does not influence high-intensity intermittent exercise performance

This study evaluated the acute effect of ischemic preconditioning (IPC) on a high-intensity intermittent exercise performance and physiological indicators in amateur soccer players. Thirteen players (21.5 ± 2 yrs) attended three trials separated by 3–5 days in a counterbalanced randomized cross-over design: IPC (4 × 5-min occlusion 220 mmHg/reperfusion 0 mmHg) in each thigh; SHAM (similar to the IPC protocol but “occlusion” at 20 mmHg) and control (seated during the same time of IPC). After 6-min of each trial (IPC, SHAM or control), the players performed the YoYo Intermittent Endurance Test level 2 (YoYoIE2). The distance covered in the YoYoIE2 (IPC 867 ± 205 m; SHAM 873 ± 212 m; control 921 ± 206 m) was not different among trials (p = 0.10), furthermore, lactate concentration and rate of perceived exertion did not differ (P > 0.05) among protocols. There were also no significant differences in either mean heart rate (HR) or peak HR (p > 0.05) for both IPC and SHAM compared to control. Therefore, we conclude that acute IPC does not influence high-intensity intermittent exercise performance in amateur soccer players and that rate of perceived exertion, heart rate and lactate do not differ between the intervention IPC, SHAM and control

Aspectos de Diferenciação entre Laboratórios Remotos e Simuladores

XLV Congresso da Associação Brasileira de Ensino de Engenharia (COBENGE2017)Os laboratórios remotos surgiram como apoio para o desenvolvimento de novos métodos de aprendizagem e ainda como suporte adicional a métodos já existentes. Ágeis e acessíveis aos estudantes demonstram ótimas soluções no cenário da educação, sendo econômicos e dinâmicos, pois possuem acesso mundial por plataformas criadas a partir da tecnologia da informação, disponibilizando a otimização do hardware com usuários remotamente distribuídos. Os laboratórios remotos dinamizam o aprendizado fazendo o mesmo mais eficiente. Facilitam e possibilitam a capacidade analítica pela percepção de diferentes resultados entre laboratórios virtuais (simuladores) e laboratórios reais por apresentarem resultados reais em circuitos com influências externas como térmica, elétrica, magnética ou eletromagnética e principalmente apresentam as não idealidades (capacitâncias, resistências e indutâncias intrínsecas) relacionadas aos aspectos construtivos de componentes eletrônicos (resistores, indutores, capacitores, trilhas e fios). Assim, este artigo propõe demonstrar por meio de experimentações práticas as diferenciações entre dados obtidos através do laboratório remoto VISIR e os simuladores PSIM e PROTEUS sendo possível verificar dados reais em experiências com circuitos que apresentam não idealidades.info:eu-repo/semantics/publishedVersio

Factors associated with the prescription of vaginal pessaries for pelvic organ prolapse

OBJECTIVE: To identify the factors associated with the prescription of vaginal pessaries (VPs) as a conservative treatment for pelvic organ prolapse (POP). METHODS: A cross-sectional study was performed during two annual urogynecology and general obstetrics and gynecology meetings in 2017 (Sa˜o Paulo, SP, Brazil). A 19-item deidentified questionnaire regarding experiences and practices in prescribing VPs for POP patients was distributed among gynecologists. Our primary outcome was the frequency of prescribing VPs as a conservative treatment for POP. The reasons for prescribing or not prescribing VPs were also investigated. Univariate and multivariate analyses with crude and adjusted odds ratios (ORs) were performed for variables associated with the prescription of pessaries. RESULTS: Three hundred forty completed surveys were analyzed. Half of the respondents (53.53%) were between 30-49 years old; most of them were female (73.53%), were from the Southeast Region (64.12%), were trained in obstetrics and gynecology (80.24%) or urogynecology (61.18%) and worked in private offices (63.42%). More than one-third (36.48%) attended four or more POP cases/week, and 97.65% (n=332) had heard or knew about VPs for POP; however, only 47.06% (n=160) prescribed or offered this treatment to patients. According to the multivariate analysis, physicians aged 18-35 years (OR=1.97[1.00-3.91]; p=0.04), those who participated in a previous urogynecology fellowship (OR=2.34[1.34-4.09]; po0.01), those with relatively high volumes of POP cases (4 or +) (OR=2.23[1.21-4.47]; p=0.01) and those with PhD degrees (OR=2.75[1.01-7.54]; p=0.05) prescribed more pessaries. CONCLUSIONS: Most gynecologists did not prescribe VPs. Younger physician age, participation in a previous urogynecology fellowship, a PhD degree, and a relatively high volume of POP cases were associated with increased VP prescription rates

AGROBIODIVERSIDADE EM QUINTAIS COMO ESTRATÉGIA PARA SOBERANIA ALIMENTAR NO SEMIÁRIDO NORTE MINEIRO

A agrobiodiversidade engloba toda diversidade biológica manejada pelos agricultores/as para produção agrícola, seus saberes e práticas ancestrais associados. Neste trabalho, investigou-se a agrobiodiversidade e suas implicações na soberania alimentar de diferentes comunidades tradicionais do norte mineiro, utilizando os quintais como foco de estudo. Para tanto, foram realizadas entrevistas semi-estruturadas em domicílios e nos respectivos quintais amostrados, reuniões e grupos focais em cada comunidade parceira, a saber: quilombola de Malhada Grande (Catuti/MG), vazanteira do Pau Preto (Matias Cardoso/MG), geraizeira do Sobrado (Rio Pardo de Minas/MG) e caatingueira do Touro (Serranópolis de Minas/MG). Em geral, segundo os parceiros, o “quintal” engloba: local ao redor da casa com plantio, criação de animais, trato diário, podendo ou não haver árvores. Nele encontram-se diferentes espaços, como a horta onde se cultivam plantas de ciclo curto. A importância local dos quintais para diversos fins foi revelada nos depoimentos, como no autossustento, permutas/partilhas de plantas e frutos, uso medicinal e loci de relações familiares e comunitárias. Registraram-se 133 etnoespécies, distribuídas em 126 espécies e 46 famílias botânicas, nos agroecossistemas de quintais estudados. Entre os diferentes usos alimentares elencados(83), organizou-se 15 categorias de preparo e consumo, nas quais se destacaram (i)consumo in natura e (ii)bebidas,  pela maior riqueza de etnoespécies. A disponibilidade temporal dessa agrobiodiversidade é marcada pela sazonalidade, que define um ciclo anual fundamental: tempo das águas e tempo das secas; representando seis meses corridos de chuvas e estiagem, respectivamente.  Em cada tempo do ciclo, as fases intermediárias revelaram maior porcentagem de etnoespécies/comunidade em produção, denotando etnoespécies e etnovariedades sazonalmente específicas, adaptadas ao clima semiárido regional. Conclui-se que os quintais, ambientes manejados, representam extensão cultural de tradições alimentares locais, revelam agrobiodiversidade notavelmente rica, cuja conservação e valorização são algumas das diversas estratégias agroalimentares que comunidades tradicionais têm para manter e garantir a alimentação, fundamentais na soberania alimentar

Apolipoprotein E polymorphism influences orthotopic liver transplantation outcomes in patients with hepatitis C virus-induced liver cirrhosis

BACKGROUND: Hepatitis C virus (HCV) infection is responsible for a chronic liver inflammation, which may cause end-stage liver disease and hepatocellular carcinoma. Apolipoprotein E (protein: ApoE, gene: APOE), a key player in cholesterol metabolism, is mainly synthesized in the liver and APOE polymorphisms may influence HCV-induced liver damage. AIM: To determine whether APOE alleles affect outcomes in HCV-infected patients with liver cirrhosis following orthotopic liver transplantation (OLT). METHODS: This was a cohort study in which 179 patients, both genders and aged 34-70 years, were included before or after (up to 10 years follow-up) OLT. Liver injury severity was assessed using different criteria, including METAVIR and models for end-stage liver disease. APOE polymorphisms were analyzed by quantitative real-time polymerase chain reaction. RESULTS: The APOE3 allele was the most common (67.3%). In inflammation severity of biopsies from 89 OLT explants and 2 patients in pre-transplant, the degree of severe inflammation (A3F4, 0.0%) was significantly less frequent than in patients with minimal and moderate degree of inflammation (≤ A2F4, 16.2%) P = 0.048, in patients carrying the APOE4 allele when compared to non-APOE4. In addition, a significant difference was also found (≤ A2F4, 64.4% vs A3F4, 0.0%; P = 0.043) and (A1F4, 57.4% vs A3F4, 0.0%; P = 0.024) in APOE4 patients when compared to APOE3 carriers. The fibrosis degree of the liver graft in 8 of 91 patients and the lack of the E4 allele was associated with more moderate fibrosis (F2) (P = 0.006). CONCLUSION: Our results suggest that the E4 allele protects against progression of liver fibrosis and degree of inflammation in HCV-infected patients

Transcriptome and gene expression analysis of three developmental stages of the coffee berry borer, Hypothenemus hampei

Coffee production is a global industry valued at approximately 173 billion US dollars. One of the main challenges facing coffee production is the management of the coffee berry borer (CBB), Hypothenemus hampei, which is considered the primary arthropod pest of coffee worldwide. Current control strategies are inefficient for CBB management. Although biotechnological alternatives, including RNA interference (RNAi), have been proposed in recent years to control insect pests, characterizing the genetics of the target pest is essential for the successful application of these emerging technologies. In this study, we employed RNA-seq to obtain the transcriptome of three developmental stages of the CBB (larva, female and male) to increase our understanding of the CBB life cycle in relation to molecular features. The CBB transcriptome was sequenced using Illumina Hiseq and assembled de novo. Differential gene expression analysis was performed across the developmental stages. The final assembly produced 29,434 unigenes, of which 4,664 transcripts were differentially expressed. Genes linked to crucial physiological functions, such as digestion and detoxification, were determined to be tightly regulated between the reproductive and nonreproductive stages of CBB. The data obtained in this study help to elucidate the critical roles that several genes play as regulatory elements in CBB development

Transcriptome and gene expression analysis of three developmental stages of the coffee berry borer, Hypothenemus hampei

Coffee production is a global industry valued at approximately 173 billion US dollars. One of the main challenges facing coffee production is the management of the coffee berry borer (CBB), Hypothenemus hampei, which is considered the primary arthropod pest of coffee worldwide. Current control strategies are inefficient for CBB management. Although biotechnological alternatives, including RNA interference (RNAi), have been proposed in recent years to control insect pests, characterizing the genetics of the target pest is essential for the successful application of these emerging technologies. In this study, we employed RNA-seq to obtain the transcriptome of three developmental stages of the CBB (larva, female and male) to increase our understanding of the CBB life cycle in relation to molecular features. The CBB transcriptome was sequenced using Illumina Hiseq and assembled de novo. Differential gene expression analysis was performed across the developmental stages. The final assembly produced 29,434 unigenes, of which 4,664 transcripts were differentially expressed. Genes linked to crucial physiological functions, such as digestion and detoxification, were determined to be tightly regulated between the reproductive and nonreproductive stages of CBB. The data obtained in this study help to elucidate the critical roles that several genes play as regulatory elements in CBB development

Transcriptome and gene expression analysis of three developmental stages of the coffee berry borer, Hypothenemus hampei

Coffee production is a global industry valued at approximately 173 billion US dollars. One of the main challenges facing coffee production is the management of the coffee berry borer (CBB), Hypothenemus hampei, which is considered the primary arthropod pest of coffee worldwide. Current control strategies are inefficient for CBB management. Although biotechnological alternatives, including RNA interference (RNAi), have been proposed in recent years to control insect pests, characterizing the genetics of the target pest is essential for the successful application of these emerging technologies. In this study, we employed RNA-seq to obtain the transcriptome of three developmental stages of the CBB (larva, female and male) to increase our understanding of the CBB life cycle in relation to molecular features. The CBB transcriptome was sequenced using Illumina Hiseq and assembled de novo. Differential gene expression analysis was performed across the developmental stages. The final assembly produced 29,434 unigenes, of which 4,664 transcripts were differentially expressed. Genes linked to crucial physiological functions, such as digestion and detoxification, were determined to be tightly regulated between the reproductive and nonreproductive stages of CBB. The data obtained in this study help to elucidate the critical roles that several genes play as regulatory elements in CBB development