Scaling properties of velocity and temperature spectra above the surface friction layer in a convective atmospheric boundary layer

International audienceWe report velocity and temperature spectra measured at nine levels from 1.42 meters up to 25.7 m over a smooth playa in Western Utah. Data are from highly convective conditions when the magnitude of the Obukhov length (our proxy for the depth of the surface friction layer) was less than 2 m. Our results are somewhat similar to the results reported from the Minnesota experiment of Kaimal et al. (1976), but show significant differences in detail. Our velocity spectra show no evidence of buoyant production of kinetic energy at at the scale of the thermal structures. We interpret our velocity spectra to be the result of outer eddies interacting with the ground, not "local free convection". We observe that velocity spectra represent the spectral distribution of the kinetic energy of the turbulence, so we use energy scales based on total turbulence energy in the convective boundary layer (CBL) to collapse our spectra. For the horizontal velocity spectra this scale is (zi ?o)2/3, where zi is inversion height and ?o is the dissipation rate in the bulk CBL. This scale functionally replaces the Deardorff convective velocity scale. Vertical motions are blocked by the ground, so the outer eddies most effective in creating vertical motions come from the inertial subrange of the outer turbulence. We deduce that the appropriate scale for the peak region of the vertical velocity spectra is (z ?o)2/3 where z is height above ground. Deviations from perfect spectral collapse under these scalings at large and small wavenumbers are explained in terms of the energy transport and the eddy structures of the flow. We find that the peaks of the temperature spectra collapse when wavenumbers are scaled using (z1/2 zi1/2). That is, the lengths of the thermal structures depend on both the lengths of the transporting eddies, ~9z, and the progressive aggregation of the plumes with height into the larger-scale structures of the CBL. This aggregation depends, in top-down fashion, on zi. The whole system is therefore highly organized, with even the smallest structures conforming to the overall requirements of the whole flow

The Distance of the First Overtone RR Lyrae Variables in the MACHO LMC Database: A New Method to Correct for the Effects of Crowding

Previous studies have indicated that many of the RR Lyrae variables in the LMC have properties similar to the ones in the Galactic globular cluster M3. Assuming that the M3 RR Lyrae variables follow the same relationships among period, temperature, amplitude and Fourier phase parameter phi31 as their LMC counterparts, we have used the M3 phi31-logP relation to identify the M3-like unevolved first overtone RR Lyrae variables in 16 fields near the LMC bar. The temperatures of these variables were calculated from the M3 logP-logTe relation so that the extinction could be derived for each star separately. Since blended stars have lower amplitudes for a given period, the period amplitude relation should be a useful tool for identifying which stars are affected by crowding. We find that the low amplitude stars are brighter. We remove them from the sample and derive an LMC distance modulus 18.49+/-0.11.Comment: 30 pages, 7 figures, accepted for publication in the Astronomical Journa

Post-transcriptional regulation of satellite cell quiescence by TTP-mediated mRNA decay.

Skeletal muscle satellite cells in their niche are quiescent and upon muscle injury, exit quiescence, proliferate to repair muscle tissue, and self-renew to replenish the satellite cell population. To understand the mechanisms involved in maintaining satellite cell quiescence, we identified gene transcripts that were differentially expressed during satellite cell activation following muscle injury. Transcripts encoding RNA binding proteins were among the most significantly changed and included the mRNA decay factor Tristetraprolin. Tristetraprolin promotes the decay of MyoD mRNA, which encodes a transcriptional regulator of myogenic commitment, via binding to the MyoD mRNA 3' untranslated region. Upon satellite cell activation, p38α/β MAPK phosphorylates MAPKAP2 and inactivates Tristetraprolin, stabilizing MyoD mRNA. Satellite cell specific knockdown of Tristetraprolin precociously activates satellite cells in vivo, enabling MyoD accumulation, differentiation and cell fusion into myofibers. Regulation of mRNAs by Tristetraprolin appears to function as one of several critical post-transcriptional regulatory mechanisms controlling satellite cell homeostasis

An Exact Solution for Static Scalar Fields Coupled to Gravity in (2+1)(2+1)-Dimensions

We obtain an exact solution for the Einstein's equations with cosmological constant coupled to a scalar, static particle in static, "spherically" symmetric background in 2+1 dimensions.Comment: 9 pages. Replaced by a revised versio

Antiretroviral therapy and HIV-associated cancers: Antiangiogenic effect of efavirenz on chick chorioallantoic membrane

Purpose: To investigate the anti-angiogenic effect of efavirenz in chick chorioallantoic membrane (CAM).Methods: Fertile eggs of the domestic fowl (Gallus gallus, variant Domesticus) were used as the in vivo vascular test environment. Experimental groups were VEGF, thalidomide (negative control), efavirenz (test drug), control 1 (treated with diluent) and control 2 (no treatment). CAM photographs were taken using a microscope camera. CAM blood vessels were scored as either “present” or “absent”.Results: There was association between treatment drugs and growth of CAM blood vessels (p < 0.05) as follows: control 1 – 100 %, control 2 – 67 %, VEGF - 83 %, thalidomide - 17 %, and efavirenz - 0 % (n = 30). Although efavirenz had absolute anti-angiogenicity and presented as a potential anti-cancer drug, there was no significant difference between the anti-angiogenicity of efavirenz (100 %) and thalidomide (83 %) (F = 1.000, p = 0.341).Conclusion: Being a first-line drug in both HAART and combination treatment of HIV-1, efavirenz may be responsible for spontaneous resolution of secondary cancers in HIV-infected patients on HAART regimen.Keywords: Efavirenz, HIV, Cancers, Angiogenesis, Chick chorioallantoic membran

Spherically symmetric Yang-Mills solutions in a (4+n)- dimensional space-time

We consider the Einstein-Yang-Mills Lagrangian in a (4+n)-dimensional space-time. Assuming the matter and metric fields to be independent of the n extra coordinates, a spherical symmetric Ansatz for the fields leads to a set of coupled ordinary differential equations. We find that for n > 1 only solutions with either one non-zero Higgs field or with all Higgs fields constant exist. We construct the analytic solutions which fulfill this conditions for arbitrary n, namely the Einstein-Maxwell-dilaton solutions. We also present generic solutions of the effective 4-dimensional Einstein-Yang-Mills-Higgs-dilaton model, which possesses n Higgs triplets coupled in a specific way to n independent dilaton fields. These solutions are the abelian Einstein-Maxwell- dilaton solutions and analytic non-abelian solutions, which have diverging Higgs fields. In addition, we construct numerically asymptotically flat and finite energy solutions for n=2.Comment: 15 Latex pages, 4 eps figures; v2: discussion of results revisite

Angle of Repose and Angle of Marginal Stability: Molecular Dyanmics of Granular Particles

We present an implementation of realistic static friction in molecular dynamics (MD) simulations of granular particles. In our model, to break contacts between two particles, one has to apply a finite amount of force, determined by the Coulomb criterion. Using a two dimensional model, we show that piles generated by avalanches have a {\it finite} angle of repose $\theta_R$ (finite slopes). Furthermore, these piles are stable under tilting by an angle smaller than a non-zero tilting angle $\theta_T$, showing that $\theta_R$ is different from the angle of marginal stability $\theta_{MS}$, which is the maximum angle of stable piles. These measured angles are compared to a theoretical approximation. We also measure $\theta_{MS}$ by continuously adding particles on the top of a stable pile.Comment: 14 pages, Plain Te

Generalized Massive Gravity and Galilean Conformal Algebra in two dimensions

Galilean conformal algebra (GCA) in two dimensions arises as contraction of two copies of the centrally extended Virasoro algebra ($t\rightarrow t, x\rightarrow\epsilon x$ with $\epsilon\rightarrow 0$). The central charges of GCA can be expressed in term of Virasoro central charges. For finite and non-zero GCA central charges, the Virasoro central charges must behave as asymmetric form $O(1)\pm O(\frac{1}{\epsilon})$. We propose that, the bulk description for 2d GCA with asymmetric central charges is given by general massive gravity (GMG) in three dimensions. It can be seen that, if the gravitational Chern-Simons coupling $\frac{1}{\mu}$ behaves as of order O($\frac{1}{\epsilon}$) or ($\mu\rightarrow\epsilon\mu$), the central charges of GMG have the above $\epsilon$ dependence. So, in non-relativistic scaling limit $\mu\rightarrow\epsilon\mu$, we calculated GCA parameters and finite entropy in term of gravity parameters mass and angular momentum of GMG.Comment: 9 page

The first Frontier Fields cluster: 4.5{\mu}m excess in a z~8 galaxy candidate in Abell 2744

We present in this letter the first analysis of a z~8 galaxy candidate found in the Hubble and Spitzer imaging data of Abell 2744, as part of the Hubble Frontier Fields legacy program. We applied the most commonly-used methods to select exceptionally high-z galaxies by combining non-detection and color-criteria using seven HST bands. We used GALFIT on IRAC images for fitting and subtracting contamination of bright nearby sources. The physical properties have been inferred from SED-fitting using templates with and without nebular emission. This letter is focussed on the brightest candidate we found (m$_{F160W}$=26.2) over the 4.9 arcmin$^2$ field of view covered by the WFC3. It shows a non-detection in the ACS bands and at 3.6{\mu}m whereas it is clearly detected at 4.5{\mu}m with rather similar depths. This break in the IRAC data could be explained by strong [OIII]+H{\beta} lines at z~8 which contribute to the 4.5{\mu}m photometry. The best photo-z is found at z~8.0$^{+0.2}_{-0.5}$, although solutions at low-redshift (z~1.9) cannot be completely excluded, but they are strongly disfavoured by the SED-fitting work. The amplification factor is relatively small at {\mu}=1.49$\pm$0.02. The Star Formation Rate in this object is ranging from 8 to 60 Mo/yr, the stellar mass is in the order of M$_{\star}$=(2.5-10) x 10$^{9}$Mo and the size is r~0.35$\pm$0.15 kpc. This object is one of the first z~8 LBG candidates showing a clear break between 3.6{\mu}m and 4.5{\mu}m which is consistent with the IRAC properties of the first spectroscopically confirmed galaxy at a similar redshift. Due to its brightness, the redshift of this object could potentially be confirmed by near infrared spectroscopy with current 8-10m telescopes. The nature of this candidate will be revealed in the coming months with the arrival of new ACS and Spitzer data, increasing the depth at optical and near-IR wavelengths.Comment: 4 pages, 2 figures, Accepted for publication in Astronomy and Astrophysics Letter

Time-Series Photometry of Globular Clusters: M62 (NGC 6266), the Most RR Lyrae-Rich Globular Cluster in the Galaxy?

We present new time-series CCD photometry, in the B and V bands, for the moderately metal-rich ([Fe/H] ~ -1.3) Galactic globular cluster (GC) M62 (NGC 6266). The present dataset is the largest obtained so far for this cluster, and consists of 168 images per filter, obtained with the Warsaw 1.3m telescope at the Las Campanas Observatory (LCO) and the 1.3m telescope of the Cerro Tololo Inter-American Observatory (CTIO), in two separate runs over the time span of three months. The procedure adopted to detect the variable stars was the optimal image subtraction method (ISIS v2.2), as implemented by Alard. The photometry was performed using both ISIS and DAOPHOT/ALLFRAME. We have identified 245 variable stars in the cluster fields that have been analyzed so far, of which 179 are new discoveries. Of these variables, 133 are fundamental mode RR Lyrae stars (RRab), 76 are first overtone (RRc) pulsators, 4 are type II Cepheids, 25 are long-period variables (LPV), 1 is an eclipsing binary, and 6 are not yet well classified. Such a large number of RR Lyrae stars places M62 among the top two most RR Lyrae-rich (in the sense of total number of RR Lyrae stars present) GCs known in the Galaxy, second only to M3 (NGC 5272) with a total of 230 known RR Lyrae stars. Since this study covers most but not all of the cluster area, it is not unlikely that M62 is in fact the most RR Lyrae-rich GC in the Galaxy. In like vein, we were also able to detect the largest sample of LPV's known in a Galactic GC. We analyze a variety of Oosterhoff type indicators for the cluster, and conclude that M62 is an Oosterhoff type I system. This is in good agreement with the moderately high metallicity of the cluster, in spite of its predominantly blue horizontal branch morphology -- which is more typical of Oosterhoff type II systems. We thus conclude that metallicity plays a key role in defining Oosterhoff type. [abridged]Comment: 22 pages, 14 figures (emulateapj format). AJ, in pres