3,168 research outputs found
Quantum chaos in nanoelectromechanical systems
We present a theoretical study of the electron-phonon coupling in suspended
nanoelectromechanical systems (NEMS) and investigate the resulting quantum
chaotic behavior. The phonons are associated with the vibrational modes of a
suspended rectangular dielectric plate, with free or clamped boundary
conditions, whereas the electrons are confined to a large quantum dot (QD) on
the plate's surface. The deformation potential and piezoelectric interactions
are considered. By performing standard energy-level statistics we demonstrate
that the spectral fluctuations exhibit the same distributions as those of the
Gaussian Orthogonal Ensemble (GOE) or the Gaussian Unitary Ensemble (GUE),
therefore evidencing the emergence of quantum chaos. That is verified for a
large range of material and geometry parameters. In particular, the GUE
statistics occurs only in the case of a circular QD. It represents an anomalous
phenomenon, previously reported for just a small number of systems, since the
problem is time-reversal invariant. The obtained results are explained through
a detailed analysis of the Hamiltonian matrix structure.Comment: 14 pages, two column
Optimal generation of Fock states in a weakly nonlinear oscillator
We apply optimal control theory to determine the shortest time in which an
energy eigenstate of a weakly anharmonic oscillator can be created under the
practical constraint of linear driving. We show that the optimal pulses are
beatings of mostly the transition frequencies for the transitions up to the
desired state and the next leakage level. The time of a shortest possible pulse
for a given nonlinearity scale with the nonlinearity parameter delta as a power
law of alpha with alpha=-0.73 +/-0.029. This is a qualitative improvement
relative to the value alpha=1 suggested by a simple Landau-Zener argument.Comment: 10 pages, 6 figure
Anomalous quantum chaotic behavior in nanoelectromechanical structures
It is predicted that for sufficiently strong electron-phonon coupling an
anomalous quantum chaotic behavior develops in certain types of suspended
electro-mechanical nanostructures, here comprised by a thin cylindrical quantum
dot (billiard) on a suspended rectangular dielectric plate. The deformation
potential and piezoelectric interactions are considered. As a result of the
electron-phonon coupling between the two systems the spectral statistics of the
electro-mechanic eigenenergies exhibit an anomalous behavior. If the center of
the quantum dot is located at one of the symmetry axes of the rectangular
plate, the energy level distributions correspond to the Gaussian Orthogonal
Ensemble (GOE), otherwise they belong to the Gaussian Unitary Ensemble (GUE),
even though the system is time-reversal invariant.Comment: 4 pages, pdf forma
Perturbation of Tunneling Processes by Mechanical Degrees of Freedom in Mesoscopic Junctions
We investigate the perturbation in the tunneling current caused by
non-adiabatic mechanical motion in a mesoscopic tunnel junction. A theory
introduced by Caroli et al. \cite{bi1,bi2,bi3} is used to evaluate second order
self-energy corrections for this non-equilibrium situation lacking
translational invariance. Inelastic signatures of the mechanical degrees of
freedom are found in the current-voltage characteristics. These give
rise to sharp features in the derivative spectrum, .Comment: 22 pages LaTeX + 3 uuencoded PS picture
Nonlinear response of a driven vibrating nanobeam in the quantum regime
We analytically investigate the nonlinear response of a damped doubly clamped
nanomechanical beam under static longitudinal compression which is excited to
transverse vibrations. Starting from a continuous elasticity model for the
beam, we consider the dynamics of the beam close to the Euler buckling
instability. There, the fundamental transverse mode dominates and a quantum
mechanical time-dependent effective single particle Hamiltonian for its
amplitude can be derived. In addition, we include the influence of a
dissipative Ohmic or super-Ohmic environment. In the rotating frame, a
Markovian master equation is derived which includes also the effect of the
time-dependent driving in a non-trivial way. The quasienergies of the pure
system show multiple avoided level crossings corresponding to multiphonon
transitions in the resonator. Around the resonances, the master equation is
solved analytically using Van Vleck perturbation theory. Their lineshapes are
calculated resulting in simple expressions. We find the general solution for
the multiple multiphonon resonances and, most interestingly, a bath-induced
transition from a resonant to an antiresonant behavior of the nonlinear
response.Comment: 25 pages, 5 figures, submitted to NJ
2018 Ottawa consensus statement : Selection and recruitment to the healthcare professions
Acknowledgments: The authors thank Tom Kinirons and Sarah Stott of Work Psychology Group for supporting the consensus group discussions and workshops, and in preparing the final manuscript. We also gratefully acknowledge Professor Lambert Schuwirth for his helpful comments on an earlier draft of this paperPeer reviewedPostprin
Quantum theory of electromechanical noise and momentum transfer statistics
A quantum mechanical theory is developed for the statistics of momentum
transferred to the lattice by conduction electrons. Results for the
electromechanical noise power in the semiclassical diffusive transport regime
agree with a recent theory based on the Boltzmann-Langevin equation. All
moments of the transferred momentum are calculated for a single-channel
conductor with a localized scatterer, and compared with the known statistics of
transmitted charge.Comment: 10 pages, 2 figure
Stamp transferred suspended graphene mechanical resonators for radio-frequency electrical readout
We present a simple micromanipulation technique to transfer suspended
graphene flakes onto any substrate and to assemble them with small localized
gates into mechanical resonators. The mechanical motion of the graphene is
detected using an electrical, radio-frequency (RF) reflection readout scheme
where the time-varying graphene capacitor reflects a RF carrier at f=5-6 GHz
producing modulation sidebands at f +/- fm. A mechanical resonance frequency up
to fm=178 MHz is demonstrated. We find both hardening/softening Duffing effects
on different samples, and obtain a critical amplitude of ~40 pm for the onset
of nonlinearity in graphene mechanical resonators. Measurements of the quality
factor of the mechanical resonance as a function of DC bias voltage Vdc
indicate that dissipation due to motion-induced displacement currents in
graphene electrode is important at high frequencies and large Vdc
A network analysis to identify pathophysiological pathways distinguishing ischaemic from non-ischaemic heart failure
Aims
Heart failure (HF) is frequently caused by an ischaemic event (e.g. myocardial infarction) but might also be caused by a primary disease of the myocardium (cardiomyopathy). In order to identify targeted therapies specific for either ischaemic or nonâischaemic HF, it is important to better understand differences in underlying molecular mechanisms.
Methods and results
We performed a biological physical proteinâprotein interaction network analysis to identify pathophysiological pathways distinguishing ischaemic from nonâischaemic HF. First, differentially expressed plasma protein biomarkers were identified in 1160 patients enrolled in the BIOSTATâCHF study, 715 of whom had ischaemic HF and 445 had nonâischaemic HF. Second, we constructed an enriched physical proteinâprotein interaction network, followed by a pathway overârepresentation analysis. Finally, we identified key network proteins. Data were validated in an independent HF cohort comprised of 765 ischaemic and 100 nonâischaemic HF patients. We found 21/92 proteins to be upâregulated and 2/92 downâregulated in ischaemic relative to nonâischaemic HF patients. An enriched network of 18 proteins that were specific for ischaemic heart disease yielded six pathways, which are related to inflammation, endothelial dysfunction superoxide production, coagulation, and atherosclerosis. We identified five key network proteins: acid phosphatase 5, epidermal growth factor receptor, insulinâlike growth factor binding proteinâ1, plasminogen activator urokinase receptor, and secreted phosphoprotein 1. Similar results were observed in the independent validation cohort.
Conclusions
Pathophysiological pathways distinguishing patients with ischaemic HF from those with nonâischaemic HF were related to inflammation, endothelial dysfunction superoxide production, coagulation, and atherosclerosis. The five key pathway proteins identified are potential treatment targets specifically for patients with ischaemic HF
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