The use of the wavelet cluster analysis for asteroid family determination

The asteroid family determination has been analysis method dependent for a longtime. A new cluster analysis based on the wavelet transform has allowed an automatic definition of families with a degree of significance versus randomness. Actually this method is rather general and can be applied to any kind of structural analysis. We will rather concentrate on the main features of the method. The analysis has been performed on the set of 4100 asteroid proper elements computed by Milani and Knezevic (see Milani and Knezevic 1990). Twenty one families have been found and influence of the chosen metric has been tested. The results have beem compared to Zappala et al.'s ones (see Zappala et al 1990) obtained by the use of a completely different method applied to the same set of data. For the first time, a good overlapping has been found between both method results, not only for the big well known families but also for the smallest ones

Analysis of the Workforce and Workplace for Rheumatology, and the Research Activities of Rheumatologists Early in Their Careers

[Excerpt] The scope and scale of clinical research is unknown for any medical or surgical specialty beyond snapshots of the broad aims and expenditures of research programs sponsored by federal agencies or the pharmaceutical industry. As a consequence, the workforce and workplace for clinical investigation is enigmatic and unexamined even after explicit warnings that an essential arm for advancing clinical practice has been disabled. The present study was designed to assess the workforce and workplace for rheumatology, and the extent and type of research prevailing among rheumatologists early in their careers. Our findings provide fresh insights about the workforce and the workplace for rheumatology, and justify interventions to address gaps in both the scope and scale of clinical research in arthritis and rheumatism

The Scope and Scale of Clinical Research Accomplished by Rheumatologists Early in Their Careers

[Excerpt] The scope and scale of clinical research is unknown for any medical or surgical specialty beyond snap shots of the broad aims and expenditures of research programs sponsored by federal agencies or the pharmaceutical industry. As a consequence, the workforce and workplace for clinical investigation is enigmatic and unexamined even after explicit warnings that an essential arm for advancing clinical practice is disabled. The present study was designed to examine the nature and extent of investigative activity prevailing among rheumatologists early in their careers. This assessment provides a lens on: i) the fraction of early career rheumatologists who engage in investigative rheumatology, ii) the scope and scale of research in musculoskeletal diseases, iii) funding available for investigative work, iv) the impact of research-intensive institutions, and NIH-K-series awards on research, and v) the demographic backgrounds of early career rheumatologists. The results provide important new insights about the early career workforce for discovery and innovation in rheumatology. The findings integrate demographic, normative, and predictive data to provide the first estimate of the scope and scale of clinical investigation within rheumatology. The results also justify interventions for promoting investigative work, and ultimately advancing the clinical practice of rheumatology

Dextran sulfate enhances the level of an oxidative DNA damage biomarker, 8-oxo-7,8-dihydro-2 0-deoxyguanosine, in rat colonic mucosa

Dextran sodium sulfate (DSS) given in drinking water can induce colonic Inflammation and produce colorectal tumors in rodents, although it is not directly genotoxic. The hypothesis that DSS can produce free radicals and induce oxidative DNA damage in colonic mucosa has been tested. In rats fed for 2 days with water containing 3% and 6% DSS, colonic Inflammation manifestations were recorded and 8-oxo-7,8-dihydro-2 0-deoxyguanosine (8-oxodGuo), a major biomarker of oxidative DNA damage, was assayed in colonic mucosa. As compared with control rats given pure water, inflammatory manifestations were seen in rats given DSS. At the same time, 8-oxodGuo levels in colonic mucosa were doubled (P , 0:001). These results suggest that formation of oxidative DNA damage in colonic mucosa depends on inflammation and maybe on the production of reactive oxygen species. This study shows that DSS can induce oxidative DNA damage within only 2 days, which could explain in part its carcinogenic properties

Marine shrimp culture industry of Thailand: operating guidelines for shrimp farms.

The marine shrimp industry in Thailand had developed a code of conduct for its operations. This code of conduct is a set of principles and processes that provides a framework to meet the industry’s goal for environmental, social, and economic responsibility. The foundation of the code of conduct is the following mission statement. The marine shrimp farming industry in Thailand is committed to producing high quality, hygienic products in a sustainable manner that provides for environmental, social, and economic benefits for the present and future generations. Policy statements have been formulated to outline actions that the industry will undertake to meet its commitments under the mission statement. These policy statements cover a broad range of topics, including: environmental protection, public consultation, regulatory compliance, location, quality and safety, continual improvement, efficiency, research and development, social responsibility, monitoring and auditing, education and training, international trade. The code of conduct is voluntary, but it has been signed by a wide variety of industry stakeholders. The code commits the signatories to specific actions, including the development of a series of operating guidelines and procedural manuals. These actions will aid the industry in carrying out its operations in a manner consistent with the objectives of the code of conduct

The Evolution of Cluster Substructure with Redshift

Using Chandra archival data, we quantify the evolution of cluster morphology with redshift. To quantify cluster morphology, we use the power ratio method developed by Buote and Tsai (1995). Power ratios are constructed from moments of the two-dimensional gravitational potential and are, therefore, related to a cluster's dynamical state. Our sample will include 40 clusters from the Chandra archive with redshifts between 0.11 and 0.89. These clusters were selected from two fairly complete flux-limited X-ray surveys (the ROSAT Bright Cluster Sample and the Einstein Medium Sensitivity Survey), and additional high-redshift clusters were selected from recent ROSAT flux-limited surveys. Here we present preliminary results from the first 28 clusters in this sample. Of these, 16 have redshifts below 0.5, and 12 have redshifts above 0.5.Comment: 5 pages, 1 figure, corrected a reference, to appear in the proceeding of Multiwavelength Cosmology, ed. M. Plioni

Combined first-principles and model Hamiltonian study of the perovskite series RMnO3 (R = La, Pr, Nd, Sm, Eu and Gd)

We merge advanced ab initio schemes (standard density functional theory, hybrid functionals and the GW approximation) with model Hamiltonian approaches (tight-binding and Heisenberg Hamiltonian) to study the evolution of the electronic, magnetic and dielectric properties of the manganite family RMnO3 (R = La, Pr, Nd, Sm, Eu and Gd). The link between first principles and tight-binding is established by downfolding the physically relevant subset of 3d bands with e_g character by means of maximally localized Wannier functions (MLWFs) using the VASP2WANNIER90 interface. The MLWFs are then used to construct a tight-binding Hamiltonian. The dispersion of the TB e_g bands at all levels are found to match closely the MLWFs. We provide a complete set of TB parameters which can serve as guidance for the interpretation of future studies based on many-body Hamiltonian approaches. In particular, we find that the Hund's rule coupling strength, the Jahn-Teller coupling strength, and the Hubbard interaction parameter U remain nearly constant for all the members of the RMnO3 series, whereas the nearest neighbor hopping amplitudes show a monotonic attenuation as expected from the trend of the tolerance factor. Magnetic exchange interactions, computed by mapping a large set of hybrid functional total energies onto an Heisenberg Hamiltonian, clarify the origin of the A-type magnetic ordering observed in the early rare-earth manganite series as arising from a net negative out-of-plane interaction energy. The obtained exchange parameters are used to estimate the Neel temperature by means of Monte Carlo simulations. The resulting data capture well the monotonic decrease of the ordering temperature down the R series, in agreement with experiments.Comment: 13 pages, 9 figures, 3 table