Two-Point, Two Component, Velocity Measurements in Turbulent Pipe Flow

An experimental study of the turbulent velocity field structure was performed in a pipe flow. The primary objective of this study was to provide a detailed velocity field structure, under isothermal conditions, for use as a reference condition for later investigations of the interactions between fluctuating velocity and temperature fields, under non-isothermal conditions, in turbulent pipe flow. Two-point, two-component (u1 and u2) velocity correlation measurements were made with hot-film (\u27x\u27 probes) anemometers separated in the radial direction as well as two-point axial component correlation measurements with axial separation. The fluctuating signals were analyzed digitally and both space and space-time correlations were calculated. Spatial scales for each velocity component were determined and then used in the modeling of two-point space correlations in terms of axisymmetric tensor forms. Finally isocorrelation curves were evaluated from the axisymmetric models to test their prediction capabilities

Neutralization of the neuromuscular activity of bothropstoxin-i, a myotoxin from Bothrops jararacussu snake venom, by a hydroalcoholic extract of Casearia sylvestris Sw. (guaçatonga)

Numerous plants are used as snakebite antidotes in Brazilian folk medicine, including Casearia sylvestris Swartz, popularly known as guaçatonga. In this study, we examined the action of a hydroalcoholic extract from C. sylvestris on the neuromuscular blockade caused by bothropstoxin-I (BthTX-I), a myotoxin from Bothrops jararacussu venom, in mouse isolated phrenic nerve-diaphragm (PND) preparations. Aqueous (8 and 12 mg/ml, n=4 and 5, respectively) and hydroalcoholic (12 mg/ml, n=12) extracts of the leaves of C. sylvestris caused facilitation in PND preparations followed by partial neuromuscular blockade. BthTX-I (20 µg/ml, n=4) caused 50% paralysis after 65±15 min (mean ± S.E.M). Preincubation (30 min at 37° C) of BthTX-I (20 µg/ml, n=4) with a concentration of the hydroalcoholic extract (4 mg/ml) that had no neuromuscular activity, such as the control (n=5), prevented the neuromuscular blockade caused by the toxin. This protection may be mediated by compounds such as flavonoids and phenols identified by thin-layer chromatography and colorimetric assays.465478Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP

Topical essential fatty acid oil on wounds: local and systemic effects

FAPESP - FUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE SÃO PAULOFUNADERM - FUNDO DE APOIO À DERMATOLOGIA DE SÃO PAULOCAPES - COORDENAÇÃO DE APERFEIÇOAMENTO DE PESSOAL E NÍVEL SUPERIORBackground The use of medicinal plants and their derivatives is increasing, and approximately one-third of all traditional herbal medicines are intended for wound treatment. Natural products used in these treatments include vegetable oils, which are rich in essential fatty acids. Once in contact with an ulcerative surface, the oil reaches the blood and lymphatic vessels, thus eliciting systemic effects. ObjectiveThis study evaluated the local and possible systemic effects of essential fatty acids (sunflower oil) applied topically to rat wounds. Methods Cutaneous punch wounds (6 mm) were produced on the dorsa of 30 rats. Saline (SS), mineral oil (MO) or essential fatty acid (EFA) solutions were applied topically. Healing was evaluated after 2, 4 and 10 days (n = 5 per group) by visual and histological/morphometric examination, second harmonic generation (SHG) microscopy, and cytokine and growth factor quantification in the scar tissue (real-time PCR) and in serum (ELISA). Results MO/EFA-treated animals had higher IGF-1, leptin, IL-6 and IFN-gamma mRNA expression and lower serum IL-6 levels than the control (SS/MO) animals. SHG analysis showed no difference in collagen density between the animals treated with MO and EFA. Conclusion EFA treatment induces topical (observed by local IGF-1, leptin, IL-6 and IFN-gamma production) and systemic effects, lowering IL-6 levels in the serum. As the oil is widely used to shorten ulcer healing time, studies are needed to evaluate the treatment safety and possible undesired effects.141115FAPESP - FUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE SÃO PAULOFUNADERM - FUNDO DE APOIO À DERMATOLOGIA DE SÃO PAULOCAPES - COORDENAÇÃO DE APERFEIÇOAMENTO DE PESSOAL E NÍVEL SUPERIORFAPESP - FUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE SÃO PAULOFUNADERM - FUNDO DE APOIO À DERMATOLOGIA DE SÃO PAULOCAPES - COORDENAÇÃO DE APERFEIÇOAMENTO DE PESSOAL E NÍVEL SUPERIOR07/59319-5015/2014043/201601P-04520-201

Determining the optimal site location of GNSS base stations

The relative positioning technique plays an essential role in Global Navigation Satellite System (GNSS) surveys. Simultaneous observation at base and rover stations eliminates the majority of error sources thus the quality of a positioning solution can be substantially improved. However, topographic obstruction is still a key issue affecting positioning quality. In this study, an integrated approach for analyzing the impact of topographic obstruction on GNSS relative positioning has been developed. By considering varied satellite geometry according to actual terrain variation, this approach can be used to realistically determine satellite visibility condition for a specific base station with respect to any rover station. Furthermore, a base station quality index (BSQI) is proposed as an explicit indication of the sufficiency in a relative positioning. By incorporating the proposed approach, one can immediately identify an optimal site location for a GNSS base station with subsequent GNSS field survey thus achieved in a more reliable and cost-efficient manner

Eccentric Exercise Leads To Glial Activation But Not Apoptosis In Mice Spinal Cords.

The aim of this investigation was to evaluate the effects of 3 overtraining (OT) protocols on the glial activation and apoptosis in the spinal cords of mice. Rodents were divided into control (C; sedentary mice), overtrained by downhill running (OTR/down), overtrained by uphill running (OTR/up) and overtrained by running without inclination (OTR). The incremental load test, ambulation test, exhaustive test and functional behavioural assessment were used as performance evaluation parameters. 36 h after the exhaustive test, the dorsal and ventral parts of the lumbar spinal cord (L4-L6) were dissected for subsequent protein analysis by immunoblotting. The OT protocols led to similar responses of some performance parameters. The ventral glial fibrillary acidic protein (GFAP) protein levels were diminished in the OTR/up and OTR compared to CT and OTR/down groups. The ventral ionized calcium binding adaptor molecule 1 (Iba-1), and the dorsal GFAP and Iba-1 protein levels were increased in the OTR/down compared to the other groups. The ratio between the cleaved capase-3/caspase-3 and cleaved caspase-9/caspase-9 measured in the spinal cord were not sensitive to the OT protocols. In summary, the OTR/down activated the glial cells in the motor (i. e. Iba-1) and sensory (i. e. GFAP and Iba-1) neurons without leading to apoptosis

Desenvolvimento ninfal de Edessa meditabunda e Chinavia ubica em estruturas reprodutivas.

Conteúdo do volume 2: Ácaros; Biologia, fisiologia, morfologia; Controle biológico com bactérias entomopatogênicas; Controle biológico com fungos entomopatológicos; Controle biológico com nematoides; Controle biológico com parasitoides; Controle biológico com predadores; Ecologia e biodiversidade; Educação e etnoentomologia; Entomologia florestal; Entomologia Forense; Entomologia médica e veterinária; Entomologia molecular; Manejo integrado de pragas; Organismos geneticamente modificados; Plantas inseticidas; Polinização; Pragas quarentenárias e invasivas; Resistência de insetos a táticas de controle; Resistência de plantas a insetos; Semioquímicos e comportamento; Sistemática e taxonomia; Tecnologia de aplicação; Controle biológico com vírus entomopatogênicos; Controle químico

Multivariate Analysis Applied to Forestry Agricultural Sciences: The Model-Directed Study

This is a literature review that aimed to find articles that exemplify and describe the use of multivariate analysis in different fields of Forest Agricultural Sciences, considering effective practices using multivariate statistical techniques for the simultaneous processing of data. For data collection were selected for the meta-analysis of 70 technical articles of which 54 were employed in the study directed to the use of multivariate techniques applied in the areas of agricultural sciences. The results showed thatstudies directed to certain areas within the Forest Agricultural Sciences exhibit some regularity in the use of multivariate analysis, and most application analyzes were more usual as the Cluster Analysis (AA) and Principal Component Analysis (PCA). Thus the use of multivariate analysis studies and evaluations of experiments in Agricultural Sciences proved to great value to allow greater clarity and better interpretation of dealing with complex phenomena

O AUTOCONCEITO E A MOTIVAÇÃO NA CONSTITUIÇÃO DA SUBJETIVIDADE: CONCEITOS E RELAÇÕES

Aborda a motivação e o autoconceito e seu papel na constituição da subjetividade, mediante um enfoque sócio-histórico baseado na análise qualitativa do estudo de caso. Utiliza como método a entrevista semi-estruturada, realizada com 19 estudantes universitários do curso de Pedagogia de duas instituições de ensino, uma pública e outra particular, de Brasília-DF. Conclui que os alunos têm uma percepção favorável do autoconceito dos estudantes com relação ao curso de Pedagogia, no que se refere à motivação para a escolha do curso, à valorização da instituição, à estrutura e à organização do curso, à oportunidade para realização da prática pedagógica e à formação direcionada à docência

O AUTOCONCEITO E A MOTIVAÇÃO NA CONSTITUIÇÃO DA SUBJETIVIDADE: CONCEITOS E RELAÇÕES

Aborda a motivação e o autoconceito e seu papel na constituição da subjetividade, mediante um enfoque sócio-histórico baseado na análise qualitativa do estudo de caso. Utiliza como método a entrevista semi-estruturada, realizada com 19 estudantes universitários do curso de Pedagogia de duas instituições de ensino, uma pública e outra particular, de Brasília-DF. Conclui que os alunos têm uma percepção favorável do autoconceito dos estudantes com relação ao curso de Pedagogia, no que se refere à motivação para a escolha do curso, à valorização da instituição, à estrutura e à organização do curso, à oportunidade para realização da prática pedagógica e à formação direcionada à docência