The evaluation of physical activity and physical fitness levels of the adolescents staying in the orphanage

In this study, it was aimed to evaluate the physical activity and physical fitness levels of the adolescents who have stayed in the orphanage, to comment on the current situation of the playfields in which adolescents have participated the sport and recreational activities and to support the legislative regulations about the administration of the orphanages. The sample of the study was 83 adolescents (n=32 girls, n=51 boys and age=15.67±1.27) from Konya Orphanage. The physical activity levels of the subjects were evaluated by Physical Activity Questionnaire for Children (CFAO) adapted to Turkish from the Physical Activity Questionnaire for Older Children (PAQ-C) developed by Crocker et al (1997). Fitnessgram Test Battery was also used for the physical fitness levels of the subjects. According to gender, it was seen that there were some statistically significant differences in favor of boys in the anthropometric and physiological features (height, weight, BMI, VO2max). As it was understood that there were no significant differences in the push-up and sit-up test scores between the boys and girls, there were significant differences in the flexibility test scores in favor of girls. According to age and gender, 18,1% (n=15) of the subjects took part in the Needs Improvement-Health Risk (NI-HR), 19,3% (n=16) of them took part in the Needs Improvement (NI), 62,7% (n=52) of them took part in the Healthy Fitness Zone (HFZ) in aerobic capacity parameter (VO2max ml/kg/min); besides in Body Mass Index (BMI) parameter 13,3% (n=11) of the subjects took part in the Needs Improvement-Health Risk (NI-HR), 15,7% (n=13) of them took part in the Needs Improvement (NI), 71,1% (n=59) of them took part in the Healthy Fitness Zone (HFZ). It was also understood that 53% (n=44) of the subjects were inactive, 32,5% (n=27) of them were mid-active, 14,5% (n=12) of them were active. As a conclusion, it was seen that the adolescents who participated in the study were healthy according to the body composition, aerobic capacity and physical fitness standards determined by The Cooper Institute (2010). However, according to the classification which was applied in view of the reference values by Tanır (2013), it was concluded that most of the adolescents were inactive or mid-active in terms of physical activity. Even though the playfields in the orphanages were efficient, it has been thought that the legislative regulations for the reformation and diversification of the current playfields and organizing the recreational activities will not only support the maintenance and improvement of the current physical fitness levels of adolescents and also cause to enhancement in their physical activity levels

The effects of Sideritis akmanii on endoplasmic reticulum stress, inflammation, and DNA damage in experimentally ER-stress-induced MCF-7 cancer cells

Cancer is one of the diseases that became a social problem that can happen with uncontrolled proliferation, growth, differentiation, and spread of cells in our body. Breast cancer, on the other hand, is one of the types of cancer with the highest incidence in women. In our study, endoplasmic reticulum (ER) stress is induced by thapsigargin (T) in MCF-7 cells and then, the effects of Sideritis akmanii acetone extract (SAE) on cell viability, ER stress, inflammation, and DNA damage were investigated. The MTT [3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide] test was used to determine the effect of SAE on cytotoxicity and the comet (SCGE; single-cell gel electrophoresis) assay was used for the effects on genotoxicity. Additionally, the mRNA expression levels of both ER stress parameters (ATF4: activating transcription factor 4, ATF6: activating transcription factor 6, PERK: protein kinase RNA-like ER kinase, GRP78: glucose-regulated protein 78) and inflammation-related parameters (TNF alpha: tumor necrosis factor-alpha, IFN-gamma: interferon-gamma, IL-6: interleukin-6, IL-8: interleukin-8, IL-12: interleukin-12) were determined by qPCR. The results showed that DNA damage levels increased as a result of T treatment, DNA damage caused by T decreased when a low dose of SAE was administered and a high dose of SAE further increased DNA damage levels. It was determined that SAE, administered in different doses with T or alone in experimental groups, increased mRNA expression levels of all ER stress and inflammatory genes compared to the control group. As a result, it has been determined that S. akmanii, especially at high doses, may exhibit anticarcinogenic effects through its effects on genotoxic, cytotoxic, and ER stress in MCF-7 cells

Elit Türk kadın hentbolcularda 30 – 15 intermittent fitness test ile anaerobik performans ilişkisinin değerlendirilmesi

Bu araştırmanın amacı elit Türk kadın hentbolcuların dayanıklılık performanslarının belirlenmesinde kullanılan saha temelli 30-15 aralıklı test (IFT) performansı ile anaerobik performans; 30 saniye Wingate Anaerobik güç ve kapasite, çeviklik T-Testi performans sonuçları ilişkilerini araştırmaktır. Çalışmaya Türkiye Süper liginde oynayan 30 kadın hentbolcu gönüllü olarak katılmış 4 tanesi çalışmayı tamamlayamamıştır. Araştırma hipotezini test etmek için kesitsel tanımlayıcı korelasyon tasarımı kullanılmıştır. Ölçümler üç ayrı günde 30-15 IFT, Çeviklik T-Test ve Wingate 30 sn Anaerobik güç ve kapasite testleri 72 saat ara ile uygulanmıştır. Araştırma hipotezini test etmek için ilk olarak 30-15 IFT performans sonuçları ile anaerobik performans ve çeviklik ilişki katsayıları hesaplanmış ve ilişki tespit edilen değişkenlerin 30-15 IFT performansını ne kadar tahmin ettiğini belirlemek için de Çoklu Doğrusal Regrasyon analiz yöntemi kullanılmıştır. Katılımcıların 30-15 dayanıklılık testi ile VO2maks kapasitelerine ulaşılmış ve oyuncuların VO2maks seviyeleri ile anaerobik güç ve kapasite arasındaki ilişkiye bakılmış bunun sonucunda yapılan regresyon analizinde, bu iki parametre arasında anlamlı bir ilişkiye rastlanılmamıştır (R2= 0,110 p>0,05). Çalışmada VO2maks ile çeviklik performansı arasındaki ilişki de incelenmiştir. Regresyon analizi bu iki parametre arasında anlamlı bir ilişki olmadığını ortaya çıkarmıştır (R2= 0,134 p>0,05). Özetle, elit kadın hentbolcularda, 30-15 IFT testinin anaerobik performans ile bir ilişkisinin olmadığı belirlenmiştir

LC-MS/MS profiles, multi-element levels and biological activities of Hypericum heterophyllum Vent

Plants belonging to the genus Hypericum L. are widely used in traditional folk medicine due to their hypericin and pseudohypericin contents. In this study, we investigated the biological activity, phenolic and elemental content of methanol and acetone extracts of sheepskin grass, Hypericum heterophyllum Vent. a species that that lacks both hypericin and pseudohypericin. The total antioxidant status of the extracts was determined by commercial kits. Antibacterial effect of extracts was investigated on seven bacterial strains. Cytotoxic effects of the extracts on lung cancer cell lines were determined by MTT (3-4,5-dimethyl-thiazolyl-2,5-diphenyltetrazolium bromide) method. Phenolic content was determined by LC-ESI-MS/MS. Elements in the plant were determined by ICP-OES. The total phenolic content and antioxidant status of the species’ methanol extract were found to be higher than the acetone extract. Both of the extracts at a concentration of 20% have an antibacterial effect, especially the antibacterial effect of acetone extract. It was determined that acetone extract has an anticarcinogenic impact depending on the dose. Chlorogenic acid, miquelianin and isoquercitrin are the most abundant flavonoids in methanol and acetone extract. The plant contains Ca, K, and Mg elements in high concentrations. The phenolic substances and elements in H. heterophyllum, widely used in our country, have been presented for the first time in the literature. Besides, it can be said that the plant has antioxidant, anticarcinogen, and antimicrobial activities due to the crucial flavonoids and elements it contain

Evliliklerde kişilerarası iletişim ilkeleri ve İslami aile dergileri üzerine bir analiz

Bu çalışmada; evliliklerde kişilerarası iletişim ilkeleri ve İslami aile dergilerinden Semerkand ve Diyanet aile dergileri üzerine içerik analizi yapılmıştır. Bu bağlamda birinci bölümde evlilik ve ailenin tanımı, evlilik türleri, kişilerarası iletişim ve kişilerarası iletişim ilkeleri açıklanmıştır. İkinci bölümde eşler arası ve aile içi iletişim ilkeleri, engelleri ve evliliklerde oluşan çatışma ve çözüm yöntemleri açıklanmıştır. Üçüncü bölümde ise, Semerkand Aile Dergisi ve Diyanet Aile Dergisi’nin bir yıllık sayıları analiz edilmiştir. Sonuç olarak İslami açıdan da eşler arası ve aile içi iletişimde ilkelerin mutlu ve huzurlu evlilik sağladığı, çatışma durumlarında çözümlenmesine büyük katkı sağladığı tespit edilmiştir.--------------------In this study, a content analysis has been carried out on the principles of interpersonal communication and Islamic family magazines; Semerkand and Diyanet. In this respect, marriage and the description of family, types of marriage, interpersonal communication and the principles of interpersonal communication are explained in the first part. In the second part, interspausal and intrafamilial communication principals, obstacles and conflicts and solution methods in marriages are explained. In the third part, annual issues of Semerkand Family Magazine and Diyanet Family Magazine are analysed. As a result; the principals also provide happy and peaceful marriage and contribute solutions for the conflicts in marriages also in terms of Islam

Evliliklerde kişilerarası iletişim ilkeleri ve İslami aile dergileri üzerine bir analiz

Bu çalışmada; evliliklerde kişilerarası iletişim ilkeleri ve İslami aile dergilerinden Semerkand ve Diyanet aile dergileri üzerine içerik analizi yapılmıştır. Bu bağlamda birinci bölümde evlilik ve ailenin tanımı, evlilik türleri, kişilerarası iletişim ve kişilerarası iletişim ilkeleri açıklanmıştır. İkinci bölümde eşler arası ve aile içi iletişim ilkeleri, engelleri ve evliliklerde oluşan çatışma ve çözüm yöntemleri açıklanmıştır. Üçüncü bölümde ise, Semerkand Aile Dergisi ve Diyanet Aile Dergisi’nin bir yıllık sayıları analiz edilmiştir. Sonuç olarak İslami açıdan da eşler arası ve aile içi iletişimde ilkelerin mutlu ve huzurlu evlilik sağladığı, çatışma durumlarında çözümlenmesine büyük katkı sağladığı tespit edilmiştir. -------------------- In this study, a content analysis has been carried out on the principles of interpersonal communication and Islamic family magazines; Semerkand and Diyanet. In this respect, marriage and the description of family, types of marriage, interpersonal communication and the principles of interpersonal communication are explained in the first part. In the second part, interspausal and intrafamilial communication principals, obstacles and conflicts and solution methods in marriages are explained. In the third part, annual issues of Semerkand Family Magazine and Diyanet Family Magazine are analysed. As a result; the principals also provide happy and peaceful marriage and contribute solutions for the conflicts in marriages also in terms of Islam

Вплив 8-тижневих базових тренувань на фізичні і фізіологічні параметри жінок-гандболісток

Purpose: Aim of this study was to investigate the effect of 8 weeks core training program on some physiological and physical parameters of handball team’s female players. Material and Methods: Volunteers were separated two groups as CTG (training group) and CG (control group). CTG was applied core strength training 30 min sessions 8 weeks and 3 days per week additionally handball trainings. CG wasn’t applied any core training. Effects of different core training regimes were compared after eight weeks with repeated measures MANOVA for the tests. Results: Neither group demonstrated difference for body composition measurements for repeated test scores and between groups comparisons. Significant difference was found BFP (body fat percentage) parameters on CTG. Sprint, agility, SLJ (standing long jump) scores did not increase in any groups and no difference was found between groups. Significance was found in VJ (vertical jump), back and leg strength, right and left hand grip strength, flexibility, balance parameters on CTG. Also significance was found in all core parameters on CTG. Conclusions: Results indicate that core trainings were very effective on performance based features especially on strength and core stability. So these exercises should be included in the training programs of female handball players.Цель: Целью данного исследования было изучение влияния программы основной тренировки в течение 8 недель на некоторые физиологические и физические параметры спортсменок гандбольной команды. Материал и методы. Спорстменки были разделены на две группы: CTG (учебная группа) и CG (контрольная группа). Для CTG была применена силовая тренировка - 30 минут занятий, 8 недель, 3 дня в неделю, дополнительно тренировки по гандболу. CG не применял никакого основного обучения. Эффекты различных основных режимов тренировок сравнивались через восемь недель с повторными измерениями MANOVA для испытаний. Результаты. Ни одна из групп не продемонстрировала различий в измерениях состава тела для повторных тестов и сравнений между группами. Значительная разница была обнаружена по показателям BFP (процентное содержание телесного жира) для CTG. Спринт, ловкость, SLJ (прыжки в длину с места) не увеличивались ни в одной группе, и не было обнаружено различий между группами. Значение было найдено в VJ (вертикальный прыжок), сила спины и ног, сила захвата правой и левой руки, гибкость, параметры баланса у CTG. Также значение было найдено во всех основных параметрах у CTG. Выводы: результаты показывают, что тренировки были очень эффективными для показателей, основанных на характеристиках на силу и стабильность. Поэтому эти упражнения должны быть включены в программы тренировок гандболисток.Мета: Метою даного дослідження було вивчення впливу програми основного тренування протягом 8 тижнів на деякі фізіологічні і фізичні параметри спортсменок гандбольної команди. Матеріал і методи. Спорстменки були розділені на дві групи: CTG (навчальна група) і CG (контрольна група). Для CTG була застосована силове тренування - 30 хвилин занять, 8 тижнів, 3 дні на тиждень, додатково тренування по гандболу. CG не застосовував ніякого основного навчання. Ефекти різних основних режимів тренувань порівнювалися через вісім тижнів з повторними вимірами MANOVA для випробувань. Результати. Жодна з груп не продемонструвала відмінностей у вимірах складу тіла для повторних тестів і порівнянь між групами. Значна різниця була виявлена за показниками BFP (процентний вміст тілесного жиру) для CTG. Спринт, спритність, SLJ (стрибки в довжину з місця) не збільшувалися в жодній групі, і не було виявлено відмінностей між групами. Значення було знайдено в VJ (вертикальний стрибок), сила спини і ніг, сила захоплення правої і лівої руки, гнучкість, параметри балансу у CTG. Також значення було знайдено у всіх основних параметрах у CTG. Висновки: результати показують, що тренування були дуже ефективними для показників, заснованих на характеристиках на силу і стабільність. Тому ці вправи повинні бути включені в програми тренувань гандболісток

Вплив силових тренувань з різною частотою на непідготовлених студентів університету

Background and Study Aim: The target of this paper was to examine the effects of strength training with different frequency on physical, performance and strength features on untrained university male students. Material and Methods: 24 subjects (age= 21.47+1.50) were divided into three groups; 8 for strength training group once a week (ST1), 8 for strength training group three times a week (ST3) and 8 for control group (CG). The training groups were applied a 6-week ST that lasted approximately 80-90 minutes for each training 3 days a week for ST3 and once a week for ST1. Analysis of intergroup, intragroup and the effect of training were carried out with repeated measures ANOVA. Significance was set at 0.05. Results: There was no difference in body weight and body mass index values in training groups, while a significant increase was found in CG. In addition, there was a significant decrease in body fat percentage and a significant increase in skeleton muscle mass without any change in body weight and body mass index in ST3. No statistical difference was seen in 10-20 m sprint and agility tests in all groups. For vertical jump, balance test for right and left leg, there was a significant difference between the pre and post-test measurements of ST1 and ST3. In standing long jump measurements, significance was seen in favor of ST3. In strength parameter, while a significant difference was detected in bench press, shoulder press and push-up due to the development of training groups, a statistically significance was found in squat and biceps curl by reason of improvement in ST3. Conclusion: As a conclusion, it can be said that 6-week strength training with different frequency applied on untrained male students has a positive effect on physical, performance and strength features.Предпосылки и цель исследования. Целью данной работы было изучение влияния силовых тренировок с различной частотой на физические, функциональные и силовые характеристики у неподготовленных студентов мужского пола в университете.Материал и методы. 24 студента (возраст = 21,47 + 1,50) были разделены на три группы; 8 для группы силовых тренировок один раз в неделю (ST1), 8 для группы силовых тренировок три раза в неделю (ST3) и 8 для контрольной группы (CG). Тренировочные группы применяли 6-недельный ST, который длился приблизительно 80-90 минут для каждой тренировки 3 дня в неделю для ST3 и один раз в неделю для ST1. Анализ межгруппового, внутригруппового и эффекта обучения проводился с повторными измерениями ANOVA. Значение было установлено на уровне 0,05.Результаты. Не было никакой разницы в значениях массы тела и индекса массы тела в тренировочных группах, в то время как значительное увеличение было обнаружено в CG. Кроме того, наблюдалось значительное снижение процента жира в организме и значительное увеличение массы скелетных мышц без какого-либо изменения массы тела и индекса массы тела при ST3. Во всех спринт-тестах и ​​тестах на ловкость во всех группах статистической разницы не наблюдалось. Для вертикального прыжка, теста баланса для правой и левой ноги, была значительная разница между измерениями ST1 и ST3 до и после теста. В измерениях прыжка в длину с места стояла важность в пользу ST3. По параметру силы, в то время как значительная разница была обнаружена в жиме лежа, жиме плечом и отжимании из-за развития тренировочных групп, статистическая значимость была обнаружена в приседаниях и в бицепсах в силу улучшения ST3.Выводы. В заключение можно сказать, что 6-недельные силовые тренировки с различной частотой, применяемые к неподготовленным ученикам-мужчинам, оказывают положительное влияние на физические, физические и силовые характеристики.Передумови та мета дослідження. Метою даної роботи було вивчення впливу силових тренувань з різною частотою на фізичні, функціональні та силові характеристики у непідготовлених студентів чоловічої статі в університеті.Матеріал і методи. 24 студента (вік = 21,47 + 1,50) були розділені на три групи; 8 для групи силових тренувань один раз в тиждень (ST1), 8 для групи силових тренувань три рази в тиждень (ST3) і 8 для контрольної групи (CG). Тренувальні групи застосовували 6-тижневий ST, який тривав приблизно 80-90 хвилин для кожного тренування 3 дні на тиждень для ST3 і один раз в тиждень для ST1. Аналіз міжгрупового, внутрішньогрупового і ефекту навчання проводився з повторними вимірами ANOVA. Значення було встановлено на рівні 0,05.Результати. Не було ніякої різниці в значеннях маси тіла та індексу маси тіла в тренувальних групах, в той час як значне збільшення було виявлено в CG. Крім того, спостерігалося значне зниження відсотка жиру в організмі і значне збільшення маси скелетних м'язів без якої-небудь зміни маси тіла та індексу маси тіла при ST3. У всіх спринт-тестах і тестах на спритність у всіх групах статистичної різниці не спостерігалося. Для вертикального стрибка, тесту балансу для правої і лівої ноги, була значна різниця між вимірами ST1 і ST3 до і після тесту. У вимірах стрибка в довжину з місця стояла важливість на користь ST3. За параметром сили, в той час як значна різниця була виявлена ​​в жимі лежачи, жимі плечем і віджиманні через розвиток тренувальних груп, статистична значимість була виявлена ​​в присідання і в біцепси в силу поліпшення ST3.Висновки. На закінчення можна сказати, що 6-тижневі силові тренування з різною частотою, що застосовуються до непідготовленим учням-чоловікам, роблять позитивний вплив на фізичні, фізичні та силові характеристики