Analysis on Characteristics of Traffic Demand about SuTong Bridge

AbstractThanks to her special geographical location, SuTong Changjiang Highway Bridge, which lies in the most economically developed area-Yangtze River Delta, becomes the vital transportation passageway to prosper the economic development between South of Jiangsu province and Zhejiang & Shanghai. This paper analyzed the characteristics of traffic demand of SuTong Bridge from different angles, such as hourly/daily/monthly/space/vehicle-types features and drew some significant conclusions, based on the particular data of traffic volume of SuTong Bridge in 2010. The conclusions comprises: the traffic demand of Sutong Bridge increased by nearly 18 thousand vehicles per month; Average monthly growth rate was 1.95%; MADT in October was the highest (1/k was up to 1.12); In addition, the spatial distribution and the motor-type proportion of river-crossing vehicles were analysed

Research progress on the role of lncRNA–miRNA networks in regulating adipogenic and osteogenic differentiation of bone marrow mesenchymal stem cells in osteoporosis

Osteoporosis (OP) is characterized by a decrease in osteoblasts and an increase in adipocytes in the bone marrow compartment, alongside abnormal bone/fat differentiation, which ultimately results in imbalanced bone homeostasis. Bone marrow mesenchymal stem cells (BMSCs) can differentiate into osteoblasts and adipocytes to maintain bone homeostasis. Several studies have shown that lncRNAs are competitive endogenous RNAs that form a lncRNA–miRNA network by targeting miRNA for the regulation of bone/fat differentiation in BMSCs; this mechanism is closely related to the corresponding treatment of OP and is important in the development of novel OP-targeted therapies. However, by reviewing the current literature, it became clear that there are limited summaries discussing the effects of the lncRNA–miRNA network on osteogenic/adipogenic differentiation in BMSCs. Therefore, this article provides a review of the current literature to explore the impact of the lncRNA–miRNA network on the osteogenic/adipogenic differentiation of BMSCs, with the aim of providing a new theoretical basis for the treatment of OP

Effects of Devoflurane and Sevoflurane on Cognitive Function in Elderly Patients Undergoing General Anesthesia

Objective: To compare effects of desflurane and sevoflurane on cognitive function in elderly patients undergoing general anesthesia. Methods Eighty elderly patients undergoing general anesthesia under open surgery were enrolled in this study, ASA I ~ II, were divided into group A (desflurane group) and group B (sevoflurane group) randomly. Intravenous drugs included midazolam 0.03 mg / kg, sufentanil 0.5ug / kg, propofol 1-2mg / kg, vecuronium 0.1 mg / kg. All patients were treated with desflurane or sevoflurane to maintain anesthesia, with depth 1.2 ~ 1.4MAC. The mini-mental state examination (MMSE) scores were recorded before operation and 1h, 6h, 12h, 24h and 48h after operation. Results The MMSE scores of the two groups had no significant difference before operation but were significantly lower than those before operation (P <0.05). The MMSE scores of patients in group recovered at 12h after operation(P <0.05). Scores of group B returned in 24h after operation. Scores of group A were higher than group B at 1 h, 6 h and 12 h after operation, the difference was statistically significant. Conclusion The recovery time of cognitive function in elderly desflurane anesthesia patients was significantly less than that of sevoflurane

Effects of the intraoperative application of dexmedetomidine on hemodynamics and cerebral oxygen metabolism of patients with cerebrovascular malformations

Circulatory stability of patients with cerebrovascular malformations during the surgery is critical to their prognosis. Anesthesia-induced intubation, tumor separation, clamping and other operations may cause severe fluctuations in blood pressure and even result in aneurysm rupture. As a highly efficient and selective adrenergic α2 receptor agonists, dexmedetomidine hydrochloride is able to regulate the release of catecholamine by means of negative feedback so as to control blood pressure. This study aims to assess the effects of dexmedetomidine hydrochloride on hemodynamics and cerebral oxygen metabolism of intraoperative patients with cerebrovascular malformations

A Single Intravenous Injection of Oxycodone Hydrochloride In The Treatment of Acute Post-operative Pain after Laparoscopic Rectal Tumor Resection

Objective: To investigate the efficacy of a single intravenous injection of oxycodone hydrochloride in patients undergoing laparoscopic rectal tumor resection with acute postoperative pain and evaluate the quality of Anesthesia recovery period. Methods: 60 patients for laparoscopic rectal tumor resection, were randomly divided into two groups (n=30 each): oxycodone hydrochloride injection group (group I) and fentanil injection group (group II). oxycodone 0.05mg / kg (saline dilution of 1mg / ml) or fentanil 0.1ug / kg was injected intravenously at the end of surgery. Assessing the OAA / S sedation grade and Prince-Henry postoperative pain scores. Results: Demographic data and anesthesia characteristics were similar in the two groups. Group II’s Prince-Henry pain score was significantly higher than the group I’s (P <0.01). Conclusion: xycodone injection can reduce the incidence of acute pain after Laparoscopic rectal tumor resection, and effectively relieve the occurred acute pain, the clinical use of oxcodone is safe and effective

A Single Intravenous Injection of Oxycodone Hydrochloride In The Treatment of Acute Post-operative Pain after Laparoscopic Rectal Tumor Resection

Objective: To investigate the efficacy of a single intravenous injection of oxycodone hydrochloride in patients undergoing laparoscopic rectal tumor resection with acute postoperative pain and evaluate the quality of Anesthesia recovery period. Methods: 60 patients for laparoscopic rectal tumor resection, were randomly divided into two groups (n=30 each): oxycodone hydrochloride injection group (group I) and fentanil injection group (group II). oxycodone 0.05mg / kg (saline dilution of 1mg / ml) or fentanil 0.1ug / kg was injected intravenously at the end of surgery. Assessing the OAA / S sedation grade and Prince-Henry postoperative pain scores. Results: Demographic data and anesthesia characteristics were similar in the two groups. Group II’s Prince-Henry pain score was significantly higher than the group I’s (P <0.01). Conclusion: xycodone injection can reduce the incidence of acute pain after Laparoscopic rectal tumor resection, and effectively relieve the occurred acute pain, the clinical use of oxcodone is safe and effective

Effects of Devoflurane and Sevoflurane on Cognitive Function in Elderly Patients Undergoing General Anesthesia

Objective: To compare effects of desflurane and sevoflurane on cognitive function in elderly patients undergoing general anesthesia. Methods Eighty elderly patients undergoing general anesthesia under open surgery were enrolled in this study, ASA I ~ II, were divided into group A (desflurane group) and group B (sevoflurane group) randomly. Intravenous drugs included midazolam 0.03 mg / kg, sufentanil 0.5ug / kg, propofol 1-2mg / kg, vecuronium 0.1 mg / kg. All patients were treated with desflurane or sevoflurane to maintain anesthesia, with depth 1.2 ~ 1.4MAC. The mini-mental state examination (MMSE) scores were recorded before operation and 1h, 6h, 12h, 24h and 48h after operation. Results The MMSE scores of the two groups had no significant difference before operation but were significantly lower than those before operation (P <0.05). The MMSE scores of patients in group recovered at 12h after operation(P <0.05). Scores of group B returned in 24h after operation. Scores of group A were higher than group B at 1 h, 6 h and 12 h after operation, the difference was statistically significant. Conclusion The recovery time of cognitive function in elderly desflurane anesthesia patients was significantly less than that of sevoflurane

Safety communication patterns in small work groups : a pilot study using social network analysis

As a project based industry, construction is portrayed through the short term and transitory nature of the industry. This is one of the factors that have been correlated to the poor safety performance of the construction industry. An essential part of safety performance, however, is the effective safety communication between all parties on construction projects. The construction industry is highly regulated due to its high incidence of work-place accidents. This is especially true of smaller building companies/enterprises where the burden of compliance to safety regulations is most onerous. The majority of current research in this topic area has focused on identifying the high risk components or the causes of increased risks. The literature on safety communication network patterns and its relation to safety performance is nevertheless minimal. Thus, this study takes the opportunity to explore the safety communication issue by analyzing the communications patterns in small workgroups. In a pilot study, through surveys with construction crews that are contributing to active construction projects in Sydney, Australia, patterns of safety communications were identified using social network analysis (SNA). The findings, though preliminary, has identified safety communication network patterns under formal communications and toolbox talks may determine a small group’s safety performance