End-to-end speech enhancement based on discrete cosine transform

Previous speech enhancement methods focus on estimating the short-time spectrum of speech signals due to its short-term stability. However, these methods often only estimate the clean magnitude spectrum and reuse the noisy phase when resynthesize speech signals, which is unlikely a valid short-time Fourier transform (STFT). Recently, DNN based speech enhancement methods mainly joint estimation of the magnitude and phase spectrum. These methods usually give better performance than magnitude spectrum estimation but need much larger computation and memory overhead. In this paper, we propose using the Discrete Cosine Transform (DCT) to reconstruct a valid short-time spectrum. Under the U-net structure, we enhance the real spectrogram and finally achieve perfect performance.Comment: 5 pages, 5 figures, ICASSP 202

A method to manufacture spiral bevel gears by equivalent completing

As a transmission part for industrial application the manufacture of spiral bevel gear is particularly important. The present machining methods for manufacturing spiral bevel gears, including the so called five-cut method and completing method, have drawbacks such as low processing efficiency, requiring complex calculations and high requirements on the machine-tool performance, respectively. To solve the above problems, an equivalent completing method is proposed to process spiral bevel gear in this paper. Firstly the machine setting parameters by completing were translated from the Cradle-type hypoid generator to Cartesian-type hypoid generator and the workpiece is swing during process. CNC motion axes expression of Cartesian-type hypoid generator were expressed as sixth-order polynomial, the influences of coefficient on the tooth surface topology were researched. Then the method to machine spiral bevel gear was put forward by reducing the swing axis of workpiece, obviously a deviation of tooth surface was caused between theoretical and axis-reduced. As a response, a flank correction model was established and the other polynomial coefficients were adjusted to eliminate the deviation. Finally simulation and cutting experiment were carried out by a numerical example. The experimental results show that the proposed method is effective and feasible. The method proposed in this paper overcome and enrich the disadvantages of existing manufacture methods of spiral bevel gear

Strong Majorana evidence of a vortex from scanning tunneling microscopy with a dissipative environment

It is predicted that a vortex in a topological superconductor contains a Majorana zero mode (MZM). The confirmative Majorana signature, i.e., the $2e^2/h$ quantized conductance, however is easily sabotaged by unavoidable interruptions, e.g. instrument broadening, non-Majorana signal, and extra particle channels. We propose to avoid the signal interruption by introducing disorder-induced dissipation that couples to the tip-sample tunneling. With dissipation involved, we highlight three features, each of which alone can provide a strong evidence to identify MZM. Firstly, dissipation suppresses a finite-energy Caroli-de Gennes-Matricon (CdGM) conductance peak into a valley, while it does not split MZM zero-bias conductance peak. Secondly, we predict a dissipation-dependent scaling feature of the zero-bias conductance peak. Thirdly, the introduced dissipation manifests the MZM signal by suppressing non-topological CdGM modes. Importantly, the observation of these features does not require a quantized conductance value $2e^2/h$.Comment: 13 pages, 5 figures with reference list update

Systematic first-principles study of impurity hybridization in NiAl

We have performed a systematic first-principles computational study of the effects of impurity atoms (boron, carbon, nitrogen, oxygen, silicon, phosporus, and sulfur) on the orbital hybridization and bonding properties in the intermetallic alloy NiAl using a full-potential linear muffin-tin orbital method. The matrix elements in momentum space were used to calculate real-space properties: onsite parameters, partial densities of states, and local charges. In impurity atoms that are empirically known to be embrittler (N and O) we found that the 2s orbital is bound to the impurity and therefore does not participate in the covalent bonding. In contrast, the corresponding 2s orbital is found to be delocalized in the cohesion enhancers (B and C). Each of these impurity atoms is found to acquire a net negative local charge in NiAl irrespective of whether they sit in the Ni or Al site. The embrittler therefore reduces the total number of electrons available for covalent bonding by removing some of the electrons from the neighboring Ni or Al atoms and localizing them at the impurity site. We show that these correlations also hold for silicon, phosporus, and sulfur.Comment: Revtex, 8 pages, 7 eps figures, to appear in Phys. Rev.

The Chinese Open Science Network (COSN): Building an Open Science Community From Scratch

Open Science is becoming a mainstream scientific ideology in psychology and related fields. However, researchers, especially early-career researchers (ECRs) in developing countries, are facing significant hurdles in engaging in Open Science and moving it forward. In China, various societal and cultural factors discourage ECRs from participating in Open Science, such as the lack of dedicated communication channels and the norm of modesty. To make the voice of Open Science heard by Chinese-speaking ECRs and scholars at large, the Chinese Open Science Network (COSN) was initiated in 2016. With its core values being grassroots-oriented, diversity, and inclusivity, COSN has grown from a small Open Science interest group to a recognized network both in the Chinese-speaking research community and the international Open Science community. So far, COSN has organized three in-person workshops, 12 tutorials, 48 talks, and 55 journal club sessions and translated 15 Open Science-related articles and blogs from English to Chinese. Currently, the main social media account of COSN (i.e., the WeChat Official Account) has more than 23,000 subscribers, and more than 1,000 researchers/students actively participate in the discussions on Open Science. In this article, we share our experience in building such a network to encourage ECRs in developing countries to start their own Open Science initiatives and engage in the global Open Science movement. We foresee great collaborative efforts of COSN together with all other local and international networks to further accelerate the Open Science movement

Nitrogen-Functionalized Graphene Nanoflakes (GNFs:N): Tunable Photoluminescence and Electronic Structures

This study investigates the strong photoluminescence (PL) and X-ray excited optical luminescence observed in nitrogen-functionalized 2D graphene nanoflakes (GNFs:N), which arise from the significantly enhanced density of states in the region of {\pi} states and the gap between {\pi} and {\pi}* states. The increase in the number of the sp2 clusters in the form of pyridine-like N-C, graphite-N-like, and the C=O bonding and the resonant energy transfer from the N and O atoms to the sp2 clusters were found to be responsible for the blue shift and the enhancement of the main PL emission feature. The enhanced PL is strongly related to the induced changes of the electronic structures and bonding properties, which were revealed by the X-ray absorption near-edge structure, X-ray emission spectroscopy, and resonance inelastic X-ray scattering. The study demonstrates that PL emission can be tailored through appropriate tuning of the nitrogen and oxygen contents in GNFs and pave the way for new optoelectronic devices.Comment: 8 pages, 6 figures (including toc figure

Review of code and phase biases in multi-GNSS positioning

A review of the research conducted until present on the subject of Global Navigation Satellite System (GNSS) hardware-induced phase and code biases is here provided. Biases in GNSS positioning occur because of imperfections and/or physical limitations in the GNSS hardware. The biases are a result of small delays between events that ideally should be simultaneous in the transmission of the signal from a satellite or in the reception of the signal in a GNSS receiver. Consequently, these biases will also be present in the GNSS code and phase measurements and may there affect the accuracy of positions and other quantities derived from the observations. For instance, biases affect the ability to resolve the integer ambiguities in Precise Point Positioning (PPP), and in relative carrier phase positioning when measurements from multiple GNSSs are used. In addition, code biases affect ionospheric modeling when the Total Electron Content is estimated from GNSS measurements. The paper illustrates how satellite phase biases inhibit the resolution of the phase ambiguity to an integer in PPP, while receiver phase biases affect multi-GNSS positioning. It is also discussed how biases in the receiver channels affect relative GLONASS positioning with baselines of mixed receiver types. In addition, the importance of code biases between signals modulated onto different carriers as is required for modeling the ionosphere from GNSS measurements is discussed. The origin of biases is discussed along with their effect on GNSS positioning, and descriptions of how biases can be estimated or in other ways handled in the positioning process are provided.QC 20170922</p

Etiologic Diagnosis of Lower Respiratory Tract Bacterial Infections Using Sputum Samples and Quantitative Loop-Mediated Isothermal Amplification

Etiologic diagnoses of lower respiratory tract infections (LRTI) have been relying primarily on bacterial cultures that often fail to return useful results in time. Although DNA-based assays are more sensitive than bacterial cultures in detecting pathogens, the molecular results are often inconsistent and challenged by doubts on false positives, such as those due to system- and environment-derived contaminations. Here we report a nationwide cohort study on 2986 suspected LRTI patients across P. R. China. We compared the performance of a DNA-based assay qLAMP (quantitative Loop-mediated isothermal AMPlification) with that of standard bacterial cultures in detecting a panel of eight common respiratory bacterial pathogens from sputum samples. Our qLAMP assay detects the panel of pathogens in 1047(69.28%) patients from 1533 qualified patients at the end. We found that the bacterial titer quantified based on qLAMP is a predictor of probability that the bacterium in the sample can be detected in culture assay. The relatedness of the two assays fits a logistic regression curve. We used a piecewise linear function to define breakpoints where latent pathogen abruptly change its competitive relationship with others in the panel. These breakpoints, where pathogens start to propagate abnormally, are used as cutoffs to eliminate the influence of contaminations from normal flora. With help of the cutoffs derived from statistical analysis, we are able to identify causative pathogens in 750 (48.92%) patients from qualified patients. In conclusion, qLAMP is a reliable method in quantifying bacterial titer. Despite the fact that there are always latent bacteria contaminated in sputum samples, we can identify causative pathogens based on cutoffs derived from statistical analysis of competitive relationship

Rescue of replication failure by Fanconi anaemia proteins

Chromosomal aberrations are often associated with incomplete genome duplication, for instance at common fragile sites, or as a consequence of chemical alterations in the DNA template that block replication forks. Studies of the cancer-prone disease Fanconi anaemia (FA) have provided important insights into the resolution of replication problems. The repair of interstrand DNA crosslinks induced by chemotherapy drugs is coupled with DNA replication and controlled by FA proteins. We discuss here the recent discovery of new FA-associated proteins and the development of new tractable repair systems that have dramatically improved our understanding of crosslink repair. We focus also on how FA proteins protect against replication failure in the context of fragile sites and on the identification of reactive metabolites that account for the development of Fanconi anaemia symptoms