19 research outputs found

    Energiindikatorer for Norge 1990-2009

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    Hovedformület med denne rapporten er ü presentere indikatorer som knytter energibruken i Norge til relevante aktivitetsmül, og dermed indikere om energibruken blir mer effektiv. Rapporten beskriver utviklingen i energibruken og energiintensiteten for Norge for perioden 1990-2009, büde pü nasjonalt nivü og for detaljerte nÌringer. Den samlede energibruken i Norge utgjorde 282 TWh i 2009. Store deler av denne energien blir brukt innenfor industrien, husholdningene, olje- og gassutvinning og veitransport. I perioden 1990-2009 steg energibruken i Norge med 28 prosent. En viktig grunn til oppgangen i energibruk i Norge er økt aktivitet innenfor olje- og gassutvinning og økt veitransport. Hovedfokuset i denne rapporten er energibruk pr enhet produksjonsverdi (aktivitetsnivü) i faste priser, ettersom vi mener det er den mest dekkende indikatoren for energiintensitet i norsk økonomi. Energibruken pr enhet produksjonsverdi har vist en nedang pü 29 prosent fra 1990 til 2009. Til sammenligning viste energibruken pr enhet bruttoprodukt (verdiskaping) en nedgang pü 17 prosent. Andre nasjonale indikatorer for energiintensitet støtter opp under bildet om fallende energiintensitet. Trenden med synkende energiintensitet gjelder ikke bare Norge, men er en trend vi finner igjen i de fleste OECD-land. Nedgangen i energiintensiteten skyldes flere forhold. Blant annet har mer energieffektivt utstyr i husholdningene og forbedret produktivitet gjennom teknologisk endring i nÌringslivet spilt en viktig rolle. Andre faktorer som har bidratt til redusert total energiintensitet er vridninger i nÌringsstrukturen mot mindre energiintensive nÌringer, mer energieffektive bygninger, høyere utetemperatur og økt arbeidskraftproduktivitet

    Colonic volume in patients with functional constipation or irritable bowel syndrome determined by magnetic resonance imaging

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    BACKGROUND: Functional constipation (FC) and irritable bowel syndrome constipation type (IBS‐C) share many similarities, and it remains unknown whether they are distinct entities or part of the same spectrum of disease. Magnetic resonance imaging (MRI) allows quantification of intraluminal fecal volume. We hypothesized that colonic volumes of patients with FC would be larger than those of patients with IBS‐C, and that both patient groups would have larger colonic volumes than healthy controls (HC). METHODS: Based on validated questionnaires, three groups of participants were classified into FC (n = 13), IBS‐C (n = 10), and HC (n = 19). The colonic volume of each subject was determined by MRI. Stool consistency was described by the Bristol stool scale and colonic transit times were assessed with radiopaque makers. KEY RESULTS: Overall, total colonic volumes were different in the three groups, HC (median 629 ml, interquartile range (IQR)(562–868)), FC (864 ml, IQR(742–940)), and IBS‐C (520 ml IQR(489–593)) (p = 0.001). Patients with IBS‐C had lower colonic volumes than patients with FC (p = 0.001) and HC (p = 0.019), but there was no difference between FC and HC (p = 0.10). Stool consistency was similar in the two patient groups, but patients with FC had longer colonic transit time than those with IBS‐C (117.6 h versus 43.2 h, p = 0.019). CONCLUSION: Patients with IBS‐C have lower total colonic volumes and shorter colonic transit times than patients with FC. Future studies are needed to confirm that colonic volume allows objective distinction between the two conditions

    Danish study of Non-Invasive testing in Coronary Artery Disease (Dan-NICAD):study protocol for a randomised controlled trial

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    BACKGROUND: Coronary computed tomography angiography (CCTA) is an established method for ruling out coronary artery disease (CAD). Most patients referred for CCTA do not have CAD and only approximately 20–30 % of patients are subsequently referred to further testing by invasive coronary angiography (ICA) or non-invasive perfusion evaluation due to suspected obstructive CAD. In cases with severe calcifications, a discrepancy between CCTA and ICA often occurs, leading to the well-described, low-diagnostic specificity of CCTA. As ICA is cost consuming and involves a risk of complications, an optimized algorithm would be valuable and could decrease the number of ICAs that do not lead to revascularization. The primary objective of the Dan-NICAD study is to determine the diagnostic accuracy of cardiac magnetic resonance imaging (CMRI) and myocardial perfusion scintigraphy (MPS) as secondary tests after a primary CCTA where CAD could not be ruled out. The secondary objective includes an evaluation of the diagnostic precision of an acoustic technology that analyses the sound of coronary blood flow. It may potentially provide better stratification prior to CCTA than clinical risk stratification scores alone. METHODS/DESIGN: Dan-NICAD is a multi-centre, randomised, cross-sectional trial, which will include approximately 2,000 patients without known CAD, who were referred to CCTA due to a history of symptoms suggestive of CAD and a low-risk to intermediate-risk profile, as evaluated by a cardiologist. Patient interview, sound recordings, and blood samples are obtained in connection with the CCTA. All patients with suspected obstructive CAD by CCTA are randomised to either stress CMRI or stress MPS, followed by ICA with fractional flow reserve (FFR) measurements. Obstructive CAD is defined as an FFR below 0.80 or as high-grade stenosis (>90 % diameter stenosis) by visual assessment. Diagnostic performance is evaluated as sensitivity, specificity, predictive values, likelihood ratios, and C statistics. Enrolment commenced in September 2014 and is expected to be complete in May 2016. DISCUSSION: Dan-NICAD is designed to assess whether a secondary perfusion examination after CCTA could safely reduce the number of ICAs where revascularization is not required. The results are expected to add knowledge about the optimal algorithm for diagnosing CAD. TRIAL REGISTRATION: Clinicaltrials.gov identifier, NCT02264717. Registered on 26 September 2014. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s13063-016-1388-z) contains supplementary material, which is available to authorized users

    Prediction of Coronary Revascularization in Stable Angina: Comparison of FFRCT With CMR Stress Perfusion Imaging.

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    OBJECTIVES: This study was designed to compare head-to-head fractional flow reserve (FFR) derived from coronary computed tomography angiography (CTA) (FFRCT) and cardiac magnetic resonance (CMR) stress perfusion imaging for prediction of standard-of-care-guided coronary revascularization in patients with stable chest pain and obstructive coronary artery disease by coronary CTA. BACKGROUND: FFRCT is a novel modality for noninvasive functional testing. The clinical utility of FFRCT compared to CMR stress perfusion imaging in symptomatic patients with coronary artery disease is unknown. METHODS: Prospective study of patients (n=110) with stable angina pectoris and 1 or more coronary stenosis ≥50% by coronary CTA. All patients underwent invasive coronary angiography. Revascularization was FFR-guided in stenoses ranging from 30% to 90%. FFRCT ≤0.80 in 1 or more coronary artery or a reversible perfusion defect (≥2 segments) by CMR categorized patients with ischemia. FFRCT and CMR were analyzed by core laboratories blinded for patient management. RESULTS: A total of 38 patients (35%) underwent revascularization. Per-patient diagnostic performance for identifying standard-of-care-guided revascularization, (95% confidence interval) yielded a sensitivity of 97% (86 to 100) for FFRCT versus 47% (31 to 64) for CMR, p  0.05, respectively. CONCLUSIONS: In patients with stable chest pain referred to invasive coronary angiography based on coronary CTA, FFRCT and CMR yielded similar overall diagnostic accuracy. Sensitivity for prediction of revascularization was highest for FFRCT, whereas specificity was highest for CMR.Danish Heart Foundation (grant no. 15-R99-A5837-22920)Health Research Fund of Central Denmark Regio

    Sammenhengen mellom dialog og sakseffektivitet i toppledergruppemøter

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    Denne studien er et selvstendig bidrag i en serie forskningsprosjekt pü teameffektivitet i ledergrupper, under ledelse av førsteamanuensis Henning Bang ved Psykologisk Institutt, Universitet i Oslo. Hensikten med denne studien var ü undersøke sammenhengen mellom graden av dialog under behandling av saker i toppledergrupper og gruppenes sakseffektivitet. Vi utførte en observasjonsstudie med et korrelasjonsdesign basert pü et datamateriale fra ütte reelle toppledergrupper fra offentlig sektor i Norge, der vi analyserte 49 saker som ble behandlet av disse toppledergruppene. Toppledergruppenes behandling av saker ble filmet og graden av dialog og graden av sakseffektivitet for hver av sakene ble kodet av to uavhengige koderpar. Vi fant en positiv og signifikant sammenheng mellom graden av dialog og ledergruppenes effektivitet ved behandling av saker i ledermøtene. Dette er et lite bidrag til dialogforskningen i ledergrupper, og styrker antakelsen om at dialog er en kommunikasjonsmüte som øker kvaliteten pü toppledergruppens prestasjoner. Større utvalg büde av ledergrupper og antall saker, samt eksperimentelle design der man müler variablene før og etter trening i dialog, bør vÌre fokus i fremtidig forskning pü dette omrüdet

    Degrading mountain permafrost in southern Norway: spatial and temporal variability of mean ground temperatures, 1999–2009

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    A ten-year record (1999–2009) of annual mean ground surface temperatures (MGSTs) and mean ground temperatures (MGTs) was analysed for 16 monitoring sites in Jotunheimen and on Dovrefjell, southern Norway. Warming has occurred at sites with cold permafrost, marginal permafrost and deep seasonal frost. Ongoing permafrost degradation is suggested both by direct temperature monitoring and indirect geophysical surveys. An increase in MGT at 6.6–9.0-m depth was observed for most sites, ranging from ~0.015 to ~ 0.095°C a-1. The greatest rate of temperature increase was for sites having MGTs slightly above 0°C. The lowest rate of increase was for marginal permafrost sites that are affected by latent heat exchange close to 0°C. Increased snow depths and an increase in winter air temperatures appear to be the most important factors controlling warming observed over the ten-year period. Geophysical surveys performed in 1999 to delineate the altitudinal limit of mountain permafrost were repeated in 2009 and 2010 and indicated the degradation of some permafrost over the intervening decade

    Twenty years of European mountain permafrost dynamics—the PACE legacy

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    This paper reviews and analyses the past 20 years of change and variability of European mountain permafrost in response to climate change based on time series of ground temperatures along a south–north transect of deep boreholes from Sierra Nevada in Spain (37°N) to Svalbard (78°N), established between 1998 and 2000 during the EU-funded PACE (Permafrost and Climate in Europe) project. In Sierra Nevada (at the Veleta Peak), no permafrost is encountered. All other boreholes are drilled in permafrost. Results show that permafrost warmed at all sites down to depths of 50 m or more. The warming at a 20 m depth varied between 1.5 °C on Svalbard and 0.4 °C in the Alps. Warming rates tend to be less pronounced in the warm permafrost boreholes, which is partly due to latent heat effects at more ice-rich sites with ground temperatures close to 0 °C. At most sites, the air temperature at 2 m height showed a smaller increase than the near-ground-surface temperature, leading to an increase of surface offsets (SOs). The active layer thickness (ALT) increased at all sites between c. 10% and 200% with respect to the start of the study period, with the largest changes observed in the European Alps. Multi-temporal electrical resistivity tomography (ERT) carried out at six sites showed a decrease in electrical resistivity, independently supporting our conclusion of ground ice degradation and higher unfrozen water content

    Thoracic Bone Mineral Density Derived from Cardiac CT Is Associated with Greater Fracture Rate

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    Background Osteoporosis is a prevalent, under-diagnosed, and treatable disease associated with increased fracture risk. Bone mineral density (BMD) derived from cardiac CT may be used to determine fracture rate. Purpose To assess the association between fracture rate and thoracic BMD derived from cardiac CT. Materials and Methods This prospective cohort study included consecutive participants referred for cardiac CT for evaluation of ischemic heart disease between September 2014 and March 2016. End of follow-up was June 30, 2018. In all participants, volumetric BMD of three thoracic vertebrae was measured by using quantitative CT software. The primary and secondary outcomes were any incident fracture and any incident osteoporosis-related fracture registered in the National Patient Registry, respectively. Hazard ratios were assessed by using BMD categorized as very low (120 mg/cm3). The study is registered at ClinicalTrials.gov (identifier: NCT02264717). Results In total, 1487 participants (mean age, 57 years ¹ 9; age range, 40-80 years; 52.5% women) were included, of whom 179 (12.0%) had very low BMD. During follow-up (median follow-up, 3.1 years; interquartile range, 2.7-3.4 years; range, 0.2-3.8 years), 80 of 1487 (5.3%) participants were diagnosed with an incident fracture and in 31 of 80 participants, the fracture was osteoporosis related. In unadjusted Cox regressions analyses, very low BMD was association with a greater rate of any fracture (hazard ratio, 2.6; 95% confidence interval [CI]: 1.4, 4.7; P = .002) and any osteoporosis-related fracture (hazard ratio, 8.1; 95% CI: 2.4, 26.7; P = .001) compared with normal BMD. After adjusting for age and sex, very low BMD remained associated with any fracture (hazard ratio, 2.1; 95% CI: 1.1, 4.2) and any osteoporosis-related fracture (hazard ratio, 4.0; 95% CI: 1.1, 14.6). Conclusion Routine cardiac CT can be used to help measure thoracic bone mineral density (BMD) to identify individuals who have low BMD and a greater fracture rate. Š RSNA, 2020 Online supplemental material is available for this article. See also the editorial by Bredella in this issue.status: publishe
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