7,043 research outputs found

    Re United Steelworkers and Vulcan Containers (Canada) Ltd

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    Employee Discharge alleging unjust discharge. Determination of quantum of damages. AWARD: In an award dated November 21, 1969, this board ordered the grievor to be reinstated in employment with compensation for loss of income except for wages she would have received in the first two weeks following her discharge by the company. Mr. Wrycraft dissented. The majority award stated that the grievor was subject to a duty to mitigate her losses so that any actual earnings and an amount equal to any earnings that she could have had if she had made a reasonable and prudent effort to find other work during the period of her discharge were to be deducted from her compensation. The working out of the exact amount of compensation was left to the parties, with the board remaining seized of the matter. The parties were unable to agree on the proper amount of compensation and the board reconvened

    Bluetongue virus infection creates light averse Culicoides vectors and serious errors in transmission risk estimates.

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    BackgroundPathogen manipulation of host behavior can greatly impact vector-borne disease transmission, but almost no attention has been paid to how it affects disease surveillance. Bluetongue virus (BTV), transmitted by Culicoides biting midges, is a serious disease of ruminant livestock that can cause high morbidity and mortality and significant economic losses. Worldwide, the majority of surveillance for Culicoides to assess BTV transmission risk is done using UV-light traps. Here we show that field infection rates of BTV are significantly lower in midge vectors collected using traps baited with UV light versus a host cue (CO2).MethodsWe collected Culicoides sonorensis midges in suction traps baited with CO2, UV-light, or CO2 + UV on three dairies in southern California to assess differences in the resulting estimated infection rates from these collections. Pools of midges were tested for BTV by qRT-PCR, and maximum likelihood estimates of infection rate were calculated by trap. Infection rate estimates were also calculated by trapping site within a dairy. Colonized C. sonorensis were orally infected with BTV, and infection of the structures of the compound eye was examined using structured illumination microscopy.ResultsUV traps failed entirely to detect virus both early and late in the transmission season, and underestimated virus prevalence by as much as 8.5-fold. CO2 + UV traps also had significantly lower infection rates than CO2-only traps, suggesting that light may repel infected vectors. We found very high virus levels in the eyes of infected midges, possibly causing altered vision or light perception. Collecting location also greatly impacts our perception of virus activity.ConclusionsBecause the majority of global vector surveillance for bluetongue uses only light-trapping, transmission risk estimates based on these collections are likely severely understated. Where national surveillance programs exist, alternatives to light-trapping should be considered. More broadly, disseminated infections of many arboviruses include infections in vectors' eyes and nervous tissues, and this may be causing unanticipated behavioral effects. Field demonstrations of pathogen-induced changes in vector behavior are quite rare, but should be studied in more systems to accurately predict vector-borne disease transmission

    Greek-Letter Membership and College Graduation: Does Race Matter?

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    Research, utilizing a nationally representative sample of 3,712 Americans, revealed that Greek-letter membership increases the probability of college graduation more for African Americans than for European Americans. Conversely, father\u27s education is a more robust predictor of educational outcomes for European Americans compared to their African American counterpart

    Analysis of Limit Cycle Oscillation Data from the Aeroelastic Test of the SUGAR Truss-Braced Wing Model

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    Research focus in recent years has been given to the design of aircraft that provide significant reductions in emissions, noise and fuel usage. Increases in fuel efficiency have also generally been attended by overall increased wing flexibility. The truss-braced wing (TBW) configuration has been forwarded as one that increases fuel efficiency. The Boeing company recently tested the Subsonic Ultra Green Aircraft Research (SUGAR) Truss-Braced Wing (TBW) wind-tunnel model in the NASA Langley Research Center Transonic Dynamics Tunnel (TDT). This test resulted in a wealth of accelerometer data. Other publications have presented details of the construction of that model, the test itself, and a few of the results of the test. This paper aims to provide a much more detailed look at what the accelerometer data says about the onset of aeroelastic instability, usually known as flutter onset. Every flight vehicle has a location in the flight envelope of flutter onset, and the TBW vehicle is not different. For the TBW model test, the flutter onset generally occurred at the conditions that the Boeing company analysis said it should. What was not known until the test is that, over a large area of the Mach number dynamic pressure map, the model displayed wing/engine nacelle aeroelastic limit cycle oscillation (LCO). This paper dissects that LCO data in order to provide additional insights into the aeroelastic behavior of the model

    Regional coastal food risk assessment for a tidally dominant, natural coastal setting: North Norfolk, southern North Sea

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    A Coastal Risk Assessment Framework (CRAF) provides two levels of coastal risk and vulnerability assessment, by combining information on the spatially variable hazard and exposure. In Phase 1, areas of greatest risk or `hotspots' are identified. In Phase 2, these hotspots are then analysed in greater detail to identify both direct and indirect extreme event impacts. This approach was applied to the barrier coastline of North Norfolk, eastern England. The CRAF identified high risk coastal hotspots on the basis of both hazard impacts (swash regime (tide + surge + wave runup) and overwash/terrestrial inundation regimes) from a 1 in 115 year return period storm and a range of land use, infrastructure, economic and social vulnerability indicators. Hazard extents and hazard severity, in some locations modified by the presence of intertidal saltmarsh, were calculated for 45, 1-2 km wide sections along the topographically complex coast. When combined with ve exposure indicators, eight hotspots were identified along the 45 km long frontage. In a 2nd phase, two of these hotspots, one a chain of small villages (Brancaster/Brancaster Staithe/Burnham Deepdale) and one a small town (Wells-next-the-Sea), were compared in more detail using a suite of coastal inundation and impact assessment models to determine both direct and indirect impacts. Hazards at this higher resolution were calculated using the 1D process-based XBeach model and the 2D LISFLOOD inundation model. Vulnerability to the hazards was calculated using the INDRA (Integrated Disruption Assessment) model with comparison of the two hotspots through the use of a Multi Criteria Analysis (MCA). The selection of hazard hotspots and comparison of hotspots using these techniques allows areas at greatest risk to be identified, of vital importance for coastal management and resource allocation

    Formation and removal of alkylthiolate self-assembled monolayers on gold in aqueous solutions

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    We report the development of novel reagents and approaches for generating recyclable biosensors. The use of aqueous media for the formation of protein binding alkylthiolate monolayers on Au surfaces results in accelerated alkylthiolate monolayer formation and improvement in monolayer integrity as visualized by fluorescence microscopy and CV techniques. We have also developed an electrocleaning protocol that is compatible with microfluidics devices, and this technique serves as an on-chip method for cleaning Au substrates both before and after monolayer formation. The techniques for the formation and dissociation of biotinylated SAMs from aqueous solvents reported here may be applied towards the development of Au-based sensor devices and microfluidics chips in the future. A potential use of these devices includes the specific capture and triggered release of target cells, proteins, or small molecules from liquid samples

    Seasonal variation and impact of waste-water lagoons as larval habitat on the population dynamics of Culicoides sonorensis (Diptera:Ceratpogonidae) at two dairy farms in northern California.

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    The Sacramento (northern Central) Valley of California (CA) has a hot Mediterranean climate and a diverse ecological landscape that is impacted extensively by human activities, which include the intensive farming of crops and livestock. Waste-water ponds, marshes, and irrigated fields associated with these agricultural activities provide abundant larval habitats for C. sonorensis midges, in addition to those sites that exist in the natural environment. Within this region, C. sonorensis is an important vector of bluetongue (BTV) and related viruses that adversely affect the international trade and movement of livestock, the economics of livestock production, and animal welfare. To characterize the seasonal dynamics of immature and adult C. sonorensis populations, abundance was monitored intensively on two dairy farms in the Sacramento Valley from August 2012- to July 2013. Adults were sampled every two weeks for 52 weeks by trapping (CDC style traps without light and baited with dry-ice) along N-S and E-W transects on each farm. One farm had large operational waste-water lagoons, whereas the lagoon on the other farm was drained and remained dry during the study. Spring emergence and seasonal abundance of adult C. sonorensis on both farms coincided with rising vernal temperature. Paradoxically, the abundance of midges on the farm without a functioning waste-water lagoon was increased as compared to abundance on the farm with a waste-water lagoon system, indicating that this infrastructure may not serve as the sole, or even the primary larval habitat. Adult midges disappeared from both farms from late November until May; however, low numbers of parous female midges were detected in traps set during daylight in the inter-seasonal winter period. This latter finding is especially critical as it provides a potential mechanism for the "overwintering" of BTV in temperate regions such as northern CA. Precise documentation of temporal changes in the annual abundance and dispersal of Culicoides midges is essential for the creation of models to predict BTV infection of livestock and to develop sound abatement strategies
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