Evolution of honesty in higher-order social networks

Sender-receiver games are simple models of information transmission that provide a formalism to study the evolution of honest signaling and deception between a sender and a receiver. In many practical scenarios, lies often affect groups of receivers, which inevitably entangles the payoffs of individuals to the payoffs of other agents in their group, and this makes the formalism of pairwise sender-receiver games inapt for where it might be useful the most. We therefore introduce group interactions among receivers and study how their interconnectedness in higher-order social networks affects the evolution of lying. We observe a number of counterintuitive results that are rooted in the complexity of the underlying evolutionary dynamics, which has thus far remained hidden in the realm of pairwise interactions. We find conditions for honesty to persist even when there is a temptation to lie, and we observe the prevalence of moral strategy profiles even when lies favor the receiver at a cost to the sender. We confirm the robustness of our results by further performing simulations on hypergraphs created from real-world data using the SocioPatterns database. Altogether, our results provide persuasive evidence that moral behavior may evolve on higher-order social networks, at least as long as individuals interact in groups that are small compared to the size of the network

Breaking survival barriers in breast cancer- A case of CNS metastasis

One in every eight women worldwide will be diagnosed to be suffering with breast cancer in their lifetime. It is vital not only to diagnose the disease early but also to refer it to a tertiary care center for the most appropriate or standard anti-cancer treatment without delay. The outcomes of such therapy can be a game changer for the patient. Screening mammography is only having a small reduction in mortality of breast cancer. Here, we present a clinical report of one patient who had Her2 Neu positive disease with early central nervous system (CNS) metastasis and responded extremely well to anti her2 Neu therapy with chemotherapy and has survived over six years now on treatment

Marginal Strength of Collarless Metal Ceramic Crown

Metal ceramic restorations have been implicated for the discoloration in area of labiogingivalmargin. Attempts to rectify this, by altering the design of metal frameworkswill lead to decrease in fracture strength atmargin. This in vitro study compared the fracture strength at margins of metal ceramic crowns cemented to metal tooth analogs. Crowns evaluated with different marginal configurations, shoulder and shoulder bevel with 0 mm, 0.5 mm, 1 mm, and 1.5 mm, were selected. Methods. Maxillary right canine typhodont tooth was prepared to receive a metal ceramic crown with shoulder margin. This was duplicated to get 20 metal teeth analogs. Then the same tooth was reprepared to get shoulder bevel configuration. These crowns were then cemented onmetal teeth analogs and tested for fracture strength atmargin on an Instron testing machine. A progressive compressive load was applied using 6.3 mm diameter rod with crosshead speed of 2.5 mm per minute. Statisticaly analysis was performed with ANOVA, Student's “t” test and “f” test. Results. The fracture strength of collarless metal ceramic crowns under study exceeded the normal biting force. Therefore it can be suggested that collarless metal ceramic crowns with shoulder or shoulder bevel margins up to 1.5 mm framework reduction may be indicated for anteriormetal ceramic restorations. Significance. k Collarless metal ceramic crowns have proved to be successful for anterior fixed restorations. Hence, it may be subjected to more clinical trials

Quantitative osteological study of a bottom feeder hillstream cyprinoid fish Crossocheilus latius latius (Hamilton- Buchanan)

The quantitative osteological study has been conducted on a Hillstream bottom feeder fish Crossocheilus latius latius. C. latius latius is a common hillstream fish of Snowfed Rivers of Alaknanda. The bones have been taken from different sized fishes ranged from 13 to 27 Cm in length and 39 to 132 gm in weight. The correlation is applied between Body Weight and the Weight of different disarticulated bones of C. latius latius. The correlation (r) is highly significant among the different parameter of body in relation to osteology which ranged from r = 0.952; P<0.1 to r = 0.999; P< 0.1

On the Design and Analysis of Parallel and Distributed Algorithms

Arrival of multicore systems has enforced a new scenario in computing, the parallel and distributed algorithms are fast replacing the older sequential algorithms, with many challenges of these techniques. The distributed algorithms provide distributed processing using distributed file systems and processing units, while network is modeled as minimum cost spanning tree. On the other hand, the parallel processing chooses different language platforms, data parallel vs. parallel programming, and GPUs. Processing units, memory elements and storage are connected through dynamic distributed networks in the form of spanning trees. The article presents foundational algorithms, analysis, and efficiency considerations.Comment: 9 page

Accuracy of impressions with different impression materials in angulated implants

Purpose: To evaluate the dimensional accuracy of the resultant (duplicative) casts made from two different impression materials (polyvinyl siloxane and polyether) in parallel and angulated implants.Materials and Methods: Three definitive master casts (control groups) were fabricated in dental stone with three implants, placed at equi-distance. In first group (control), all three implants were placed parallel to each other and perpendicular to the plane of the cast. In the second and third group (control), all three implants were placed at 10° and 15° angulation respectively to the long axis of the cast, tilting towards the centre. Impressions were made with polyvinyl siloxane and polyether impression materials in a special tray, using a open tray impression technique from the master casts. These impressions were poured to obtain test casts. Three reference distances were evaluated on each test cast by using a profile projector and compared with control groups to determine the effect of combined interaction of implant angulation and impression materials on the accuracy of implant resultant cast.Results: Statistical analysis revealed no significant difference in dimensional accuracy of the resultant casts made from two different impression materials (polyvinyl siloxane and polyether) by closed tray impression technique in parallel and angulated implants.Conclusion: On the basis of the results of this study, the use of both the impression materials i.e., polyether and polyvinyl siloxane impression is recommended for impression making in parallel as well as angulated implants.Key words: Angulated implants, implant impression, impression accuracy, impression materia

Compartment syndrome of the hand: A case report and review of literature

© 2017 The Authors Elevation of pressure within tightly bound myofascial compartments has detrimental consequences if not treated promptly, leading to a loss of circulation, ischemia, myonecrosis, nerve damage, and limb loss. They are commonly seen in the distal upper and lower extremities; however, compartment syndrome of the hand is rarely encountered and prompt recognition can prevent permanent damage and tissue loss. This case study presents a complicated case of compartment syndrome of the hand and discusses the interrelationship between compartment syndrome and rhabdomyolysis. An emphasis is placed on pathophysiology of this relationship to allow a better understanding of the imaging features as well as early clinical recognition of compartment syndrome. Magnetic resonance imaging findings are specifically discussed as it remains the best imaging tool to evaluate the extent of the damage and surgical planning

First hospital outbreak of the globally emerging Candida auris in a European hospital

Background: Candida auris is a globally emerging multidrug resistant fungal pathogen causing nosocomial transmission. We report an ongoing outbreak of C. auris in a London cardio-thoracic center between April 2015 and July 2016. This is the first report of C. auris in Europe and the largest outbreak so far. We describe the identification, investigation and implementation of control measures. Methods: Data on C. auris case demographics, environmental screening, implementation of infection prevention/control measures, and antifungal susceptibility of patient isolates were prospectively recorded then analysed retrospectively. Speciation of C. auris was performed by MALDI-TOF and typing of outbreak isolates performed by amplified fragment length polymorphism (AFLP). Results: This report describes an ongoing outbreak of 50 C. auris cases over the first 16 month (April 2015 to July 2016) within a single Hospital Trust in London. A total of 44 % (n = 22/50) patients developed possible or proven C. auris infection with a candidaemia rate of 18 % (n = 9/50). Environmental sampling showed persistent presence of the yeast around bed space areas. Implementation of strict infection and prevention control measures included: isolation of cases and their contacts, wearing of personal protective clothing by health care workers, screening of patients on affected wards, skin decontamination with chlorhexidine, environmental cleaning with chorine based reagents and hydrogen peroxide vapour. Genotyping with AFLP demonstrated that C. auris isolates from the same geographic region clustered. Conclusion: This ongoing outbreak with genotypically closely related C. auris highlights the importance of appropriate species identification and rapid detection of cases in order to contain hospital acquired transmission

MALDI-TOF MS: the proteomic approach, the future of fungal identification in India

Background: India, being a country where fungal infections are rampant, is urgently in need of effective tools for early and accurate diagnosis of fungal infections. Matrix-assisted Laser Desorption Ionization Time-of-Flight Mass Spectrometry (MALDI-TOF-MS) is a recent method which has shown potential in identifying clinically important bacterial pathogens as well as clinically important fungi. The main objective of this study was to compare the utility of MALDI-TOF MS for the identification of fungi against that of conventional methods.Methods: The project was carried out in a tertiary care government hospital in India. Fifty clinical isolates comprising mainly various yeast species were subjected to conventional identification (Phenotypic) as well as MALDI-TOF-MS. Their results were further compared.Results: MALDI-TOF MS showed a high concordance with conventional methods while identifying species like C. albicans, C. tropicalis, C. parapsilosis and C. neoformans, although the concordance for species such as Rhodotorula and Trichosporon could only be matched up to genus level.Conclusions: MALDI-TOF MS-based identification is both a rapid and a viable tool for identification of clinically relevant yeast species with good correlation to conventional methods and a quick turnaround time