Effects of partial ionization on magnetic flux emergence in the Sun

We have performed 3-D numerical simulations to investigate the effect of partial ionization on the process of magnetic flux emergence. In our study, we have modified the single-fluid MHD equations to include the presence of neutrals and have performed two basic experiments: one that assumes a fully ionized plasma (FI case) and one that assumes a partially ionized plasma (PI case). We find that the PI case brings less dense plasma to and above the solar surface. Furthermore, we find that partial ionization alters the emerging magnetic field structure, leading to a different shape of the polarities in the emerged bipolar regions compared to the FI case. The amount of emerging flux into the solar atmosphere is larger in the PI case, which has the same initial plasma beta as the FI case, but a larger initial magnetic field strength. The expansion of the field above the photosphere occurs relatively earlier in the PI case, and we confirm that the inclusion of partial ionization reduces cooling due to adiabatic expansion. However, it does not appear to work as a heating mechanism for the atmospheric plasma. The performance of these experiments in three dimensions shows that PI does not prevent the formation of unstable magnetic structures, which erupt into the outer solar atmosphere

Parallelism and the software-hardware interface in embedded systems

This thesis by publications addresses issues in the architecture and microarchitecture of next generation, high performance streaming Systems-on-Chip through quantifying the most important forms of parallelism in current and emerging embedded system workloads. The work consists of three major research tracks, relating to data level parallelism, thread level parallelism and the software-hardware interface which together reflect the research interests of the author as they have been formed in the last nine years. Published works confirm that parallelism at the data level is widely accepted as the most important performance leverage for the efficient execution of embedded media and telecom applications and has been exploited via a number of approaches the most efficient being vectorlSIMD architectures. A further, complementary and substantial form of parallelism exists at the thread level but this has not been researched to the same extent in the context of embedded workloads. For the efficient execution of such applications, exploitation of both forms of parallelism is of paramount importance. This calls for a new architectural approach in the software-hardware interface as its rigidity, manifested in all desktop-based and the majority of embedded CPU's, directly affects the performance ofvectorized, threaded codes. The author advocates a holistic, mature approach where parallelism is extracted via automatic means while at the same time, the traditionally rigid hardware-software interface is optimized to match the temporal and spatial behaviour of the embedded workload. This ultimate goal calls for the precise study of these forms of parallelism for a number of applications executing on theoretical models such as instruction set simulators and parallel RAM machines as well as the development of highly parametric microarchitectural frameworks to encapSUlate that functionality.EThOS - Electronic Theses Online ServiceGBUnited Kingdo

Anterior cruciate ligament reconstruction with a quadrupled hamstrings tendon autograft does not restore tibial rotation to normative levels during landing from a jump and subsequent pivoting

Aim. Recent research suggested that the anterior curciate ligament (ACL) reconstruction does not restore tibial rotation to normal levels when a bone patellar tendon bone (BPTB) graft is used during high demanding activities. Our goal was to determine if the usage of an alternative graft, as the quadrupled semitendinosus-gracilis (ST/G), restore tibial rotation to normal values in a population of athletically active individuals while performing a usual for their sport activity. Methods. Eleven subjects, all reconstructed with an ST/G graft, were assessed in vivo, 9 months postoperatively, while they jumped off a 40 cm platform, landed on the ground and subsequently pivoted at 90 degrees. The evaluation period was identified from initial foot contact with the ground, included the pivoting of the ipsilateral leg, and was completed upon touch-down of the contralateral leg. By that time the patients had already returned to their sports activities. Results. The maximum range of motion of the tibial rotation for the pivoting leg, during the evaluation period was found significantly (P=0.0001) larger in the reconstructed leg as compared to the intact contralateral, although both clinical and arthrometer assessments revealed restoration of anterior translation. Conclusion. It was concluded that ACL reconstruction with an ST/G graft does not restore tibial rotation to normal levels during this high demanding activity. It seems that new surgical techniques are needed to better replicate the actual anatomy and function of the natural ACL in order to address this problem

Wave-resistance computation via CFD and IGA-BEM solvers : a comparative study

This paper delivers a preliminary comparative study on the computation of wave resistance via a commercial CFD solver (STAR-CCM+®) versus an in-house developed IGA-BEM solver for a pair of hulls, namely the parabolic Wigley hull and the KRISO container ship (KCS). The CFD solver combines a VOF (Volume Of Fluid) free-surface modelling technique with alternative turbulence models, while the IGA-BEM solver adopts an inviscid flow model that combines the Boundary Element approach (BEM) with Isogeometric Analysis (IGA) using T-splines or NURBS. IGA is a novel and expanding concept, introduced by Hughes and his collaborators (Hughes et al, 2005), aiming to intrinsically integrate CAD with Analysis by communicating the CAD model of the geometry (the wetted ship hull in our case) to the solver without any approximation

A remote approach to measure blood perfusion from the human face

A CMOS camera-based imaging photoplethysmography (PPG) system has been previously demonstrated for the contactless measurement of skin blood perfusion over a wide tissue area. An improved system with a more sensitive CCD camera and a multi-wavelength RCLED ring light source was developed to measure blood perfusion from the human face. The signals acquired by the PPG imaging system were compared to signals captured concurrently from a conventional PPG finger probe. Experimental results from eight subjects demonstrate that the camera-based PPG imaging technique is able to measure pulse rate and blood perfusion

BioThreads: a novel VLIW-based chip multiprocessor for accelerating biomedical image processing applications

We discuss BioThreads, a novel, configurable, extensible system-on-chip multiprocessor and its use in accelerating biomedical signal processing applications such as imaging photoplethysmography (IPPG). BioThreads is derived from the LE1 open-source VLIW chip multiprocessor and efficiently handles instruction, data and thread-level parallelism. In addition, it supports a novel mechanism for the dynamic creation, and allocation of software threads to uncommitted processor cores by implementing key POSIX Threads primitives directly in hardware, as custom instructions. In this study, the BioThreads core is used to accelerate the calculation of the oxygen saturation map of living tissue in an experimental setup consisting of a high speed image acquisition system, connected to an FPGA board and to a host system. Results demonstrate near-linear acceleration of the core kernels of the target blood perfusion assessment with increasing number of hardware threads. The BioThreads processor was implemented on both standard-cell and FPGA technologies; in the first case and for an issue width of two, full real-time performance is achieved with 4 cores whereas on a mid-range Xilinx Virtex6 device this is achieved with 10 dual-issue cores. An 8-core LE1 VLIW FPGA prototype of the system achieved 240 times faster execution time than the scalar Microblaze processor demonstrating the scalability of the proposed solution to a state-of-the-art FPGA vendor provided soft CPU core

Remote simultaneous dual wavelength imaging photoplethysmography: a further step towards 3-D mapping of skin blood microcirculation

This paper presents a camera-based imaging photoplethysmographic (PPG) system in the remote detection of PPG signals, which can contribute to construct a 3-D blood pulsation mapping for the assessment of skin blood microcirculation at various vascular depths. Spot measurement and contact sensor have been currently addressed as the primary limitations in the utilization of conventional PPG system. The introduction of the fast digital camera inspires the development of the imaging PPG system to allow ideally non-contact monitoring from a larger field of view and different tissue depths by applying multi-wavelength illumination sources. In the present research, the imaging PPG system has the capability of capturing the PPG waveform at dual wavelengths simultaneously: 660 and 880nm. A selected region of tissue is remotely illuminated by a ring illumination source (RIS) with dual-wavelength resonant cavity light emitting diodes (RCLEDs), and the backscattered photons are captured by a 10-bit CMOS camera at a speed of 21 frames/second for each wavelength. The waveforms from the imaging system exhibit comparable functionality characters with those from the conventional contact PPG sensor in both time domain and frequency domain. The mean amplitude of PPG pulsatile component is extracted from the PPG waveforms for the mapping of blood pulsation in a 3-D format. These results strongly demonstrate the capability of the imaging PPG system in displaying the waveform and the potential in 3-D mapping of blood microcirculation by a non-contact means

Real-time VLSI architecture for bio-medical monitoring

This paper discusses the architecture and implementation of SSS2, a high-performance real-time signal processing system developed with a hybrid ESL/RTL methodology and targeted to biomedical image processing. Traditional methodologies, as well as new tools, such as Cebatech's C2R untimed-C synthesizer have been employed in the design of the system. The SSS2 platform specifies a parametric number of scalar processing elements, based on multiple 32-bit Sparc-compliant engines, augmented with LE2, an ESL-designed 2-way LIW/SIMD accelerator. LE2, which is purely designed in C, exposes a consistent interface to its SIMD datapath directly which is directly derived from the C-source of open-source image processing codes. It is synthesized to Verilog RTL with C2R. Behaviorally-synthesized SIMD datapaths are then 'plugged-in' into the exposed LE2 datapath interface. The LE2 memory interface can be either a cache- based configurable vector load/store unit or a multi-banked, multi-channel streaming local memory system. Results drawn from this work strongly suggest a shift towards a hybrid approach in designing multi-core systems for high bandwidth streaming and for dealing with large scale medical image transfers and non-linear bio-signal processing algorithms

Possible relationship between Seismic Electric Signals (SES) lead time and earthquake stress drop

Stress drop values for fourteen large earthquakes with MW ≥ 5.4 which occurred in Greece during the period 1983–2007 are available. All these earthquakes were preceded by Seismic Electric Signals (SES). An attempt has been made to investigate possible correlation between their stress drop values and the corresponding SES lead times. For the stress drop, we considered the Brune stress drop, ΔσB, estimated from far field body wave displacement source spectra and ΔσSB derived from the strong motion acceleration response spectra. The results show a relation may exist between Brune stress drop, ΔσB, and lead time which implies that earthquakes with higher stress drop values are preceded by SES with shorter lead time

The efficacy of iron chelator regimes in reducing cardiac and hepatic iron in patients with thalassaemia major: a clinical observational study

<p>Abstract</p> <p>Background</p> <p>Available iron chelation regimes in thalassaemia may achieve different changes in cardiac and hepatic iron as assessed by MR. The aim of this study was to assess the efficacy of four available iron chelator regimes in 232 thalassaemia major patients by assessing the rate of change in repeated measurements of cardiac and hepatic MR.</p> <p>Results</p> <p>For the heart, deferiprone and the combination of deferiprone and deferoxamine significantly reduced cardiac iron at all levels of iron loading. As patients were on deferasirox for a shorter time, a second analysis ("Initial interval analysis") assessing the change between the first two recorded MR results for both cardiac and hepatic iron (minimum interval 12 months) was made. Combination therapy achieved the most rapid fall in cardiac iron load at all levels and deferiprone alone was significantly effective with moderate and mild iron load. In the liver, deferasirox effected significant falls in iron load and combination therapy resulted in the most rapid decline.</p> <p>Conclusion</p> <p>With the knowledge of the efficacy of the different available regimes and the specific iron load in the heart and the liver, appropriate tailoring of chelation therapy should allow clearance of iron. Combination therapy is best in reducing both cardiac and hepatic iron, while monotherapy with deferiprone or deferasirox are effective in the heart and liver respectively. The outcomes of this study may be useful to physicians as to the chelation they should prescribe according to the levels of iron load found in the heart and liver by MR.</p