Phase Statistics of Soliton

The characteristic function of soliton phase jitter is found analytically when the soliton is perturbed by amplifier noise. In additional to that from amplitude jitter, the nonlinear phase noise due to frequency and timing jitter is also analyzed. Because the nonlinear phase noise is not Gaussian distributed, the overall phase jitter is also non-Gaussian. For a fixed mean nonlinear phase shift, the contribution of nonlinear phase noise from frequency and timing jitter decreases with distance and signal-to-noise ratio.Comment: 8 pages, submitted to JOSA

CHAP : Enabling efficient hardware-based multiple hash schemes for IP lookup

Building a high performance IP lookup engine remains a challenge due to increasingly stringent throughput requirements and the growing size of IP tables. An emerging approach for IP lookup is the use of set associative memory architecture, which is basically a hardware implementation of an open addressing hash table with the property that each row of the hash table can be searched in one memory cycle. While open addressing hash tables, in general, provide good average-case search performance, their memory utilization and worst-case performance can degrade quickly due to bucket overflows. This paper presents a new simple hash probing scheme called CHAP (Content-based HAsh Probing) that tackles the hash overflow problem. In CHAP, the probing is based on the content of the hash table, thus avoiding the classical side effects of probing. We show through experimenting with real IP tables how CHAP can effectively deal with the overflow. © IFIP International Federation for Information Processing 2009

Alpha-tocopherol exerts protective function against the mucotoxicity of particulate matter in amphibian and human goblet cells

Exposure to particulate matter (PM) in ambient air is known to increase the risk of cardiovascular disorders and mortality. The cytotoxicity of PM is mainly due to the abnormal increase of reactive oxygen species (ROS), which damage cellular components such as DNA, RNA, and proteins. The correlation between PM exposure and human disorders, including mortality, is based on long-term exposure. In this study we have investigated acute responses of mucus-secreting goblet cells upon exposure to PM derived from a heavy diesel engine. To this end, we employed the mucociliary epithelium of amphibian embryos and human Calu-3 cells to examine PM mucotoxicity. Our data suggest that acute exposure to PM significantly impairs mucus secretion and results in the accumulation of mucus vesicles in the cytoplasm of goblet cells. RNA-seq analysis revealed that acute responses to PM exposure significantly altered gene expression patterns; however, known regulators of mucus production and the secretory pathway were not significantly altered. Interestingly, pretreatment with alpha-tocopherol nearly recovered the hyposecretion of mucus from both amphibian and human goblet cells. We believe this study demonstrates the mucotoxicity of PM and the protective function of alpha-tocopherol on mucotoxicity caused by acute PM exposure from heavy diesel engines

Fortnightly variability of horizontal salinity gradient affects exchange flow in the Sumjin River estuary

The horizontal salinity gradient has been reported to play a crucial role in fortnightly variability of estuarine exchange flow in short estuaries. However, spatiotemporal variations in the salinity gradient and exchange flow have not been examined over an entire short estuary, as only data observed only at specific points was available. We analyzed the variation in salinity gradient along the entire Sumjin River estuary and its effect on the exchange flow over fortnightly tidal cycles based on observations and numerical model experiments. The salinity gradient and exchange flow were in different phases between the lower and upper estuaries by 6–7 days. The maximum salinity gradient periodically reciprocated along the channel as a result of salt flux changes determined by vertical mixing. The stronger exchange flow (> 0.04 m s-1) changed location from mouth to head of estuary while the tidal range decreased, resulting from variability of the salinity gradient. The horizontal salinity gradient is large enough to overwhelm the vertical mixing effect on the exchange flow. The spatiotemporal changes of strong exchange flow correspond well with the horizontal Richardson number value (> 3). This study suggests that for the health of estuarine ecosystems, it is important to determine the spatiotemporal variation in exchange flow throughout the estuary

Cyclin Y inhibits plasticity-induced AMPA receptor exocytosis and LTP

Cyclin Y (CCNY) is a member of the cyclin protein family, known to regulate cell division in proliferating cells. Interestingly, CCNY is expressed in neurons that do not undergo cell division. Here, we report that CCNY negatively regulates long-term potentiation (LTP) of synaptic strength through inhibition of AMPA receptor trafficking. CCNY is enriched in postsynaptic fractions from rat forebrain and is localized adjacent to postsynaptic sites in dendritic spines in rat hippocampal neurons. Using live-cell imaging of a pH-sensitive AMPA receptor, we found that during LTP-inducing stimulation, CCNY inhibits AMPA receptor exocytosis in dendritic spines. Furthermore, CCNY abolishes LTP in hippocampal slices. Taken together, our findings demonstrate that CCNY inhibits plasticity-induced AMPA receptor delivery to synapses and thereby blocks LTP, identifying a novel function for CCNY in post-mitotic cells

Mind the gaps: age and cause specific mortality and life expectancy in the older population of South Korea and Japan.

BACKGROUND: Recent life expectancy gains in high-income Asia-pacific countries have been largely the result of postponement of death from non-communicable diseases in old age, causing rapid demographic ageing. This study compared and quantified age- and cause-specific contributions to changes in old-age life expectancy in two high-income Asia-pacific countries with ageing populations, South Korea and Japan. METHODS: This study used Pollard's actuarial method of decomposing life expectancy to compare age- and cause-specific contributions to changes in old-age life expectancy between South Korea and Japan during 1997 and 2017. RESULTS: South Korea experienced rapid population ageing, and the gaps in life expectancy at 60 years old between South Korea and Japan were reduced by 2.47 years during 1997 and 2017. Decomposition analysis showed that mortality reductions from non-communicable diseases in South Korea were the leading causes of death contributing to the decreased gaps in old-age life expectancy between the two countries. More specifically, mortality reductions from cardiovascular diseases (stroke, ischaemic and hypertensive heart disease) and cancers (stomach, liver, lung, pancreatic cancers) in South Korea contributed to the decreased gap by 1.34 and 0.41 years, respectively. However, increased mortality from Alzheimer and dementia, lower respiratory tract disease, self-harm and falls in South Korea widened the gaps by 0.41 years. CONCLUSIONS: Age- and cause- specific contributions to changes in old-age life expectancy can differ between high-income Asia-pacific countries. Although the gaps in old-age life expectancy between high-income Asia-pacific countries are primarily attributed to mortality changes in non-communicable diseases, these countries should also identify potential emerging threats of communicable diseases and injuries along with demographic ageing in pursuit of healthy life years in old age

Solution of the Three--Anyon Problem

We solve, by separation of variables, the problem of three anyons with a harmonic oscillator potential. The anyonic symmetry conditions from cyclic permutations are separable in our coordinates. The conditions from two-particle transpositions are not separable, but can be expressed as reflection symmetry conditions on the wave function and its normal derivative on the boundary of a circle. Thus the problem becomes one-dimensional. We solve this problem numerically by discretization. $N$-point discretization with very small $N$ is often a good first approximation, on the other hand convergence as $N\to\infty$ is sometimes very slow.Comment: 15 pages, LaTeX2.0