52 research outputs found

    The April 16 2016 Mw7.8 Muisne Earthquake in Ecuador – Preliminary Observations from the EEFIT Reconnaissance Mission of May 24 - June 7

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    On April 16 2016 an Mw7.8 earthquake with epicentre 29km south-southeast of Muisne in northern Manabí caused around 700 fatalities, injured 30,000 and destroyed several sections of the towns of Pedernales, Portoviejo, Canoa, Bahía de Caráquez and Manta, most of them important centres of tourism on the coast of Ecuador. During May 24-June 7 a team was deployed by the Earthquake Engineering Field Investigation Team (EEFIT) with the objective of surveying the damage and recording observations that would help the scientific and professional community understand the event and its consequences. The team, all co-authors of this paper, investigated structural damage patterns, surveyed 1,332 buildings, validated landslide data obtained from satellite imagery for 30 sites, and interviewed 120 families at 3 shelters. The damage observed in low- and mid-rise buildings seems to correlate well with the spectral response measured in Manta, Portoviejo, and Pedernales. Satellite-based landslide identification proved effective in an 80-90% of the cases investigated. The immediate unemployment spike, based on our limited survey, seemed to reach about 50% in the affected population

    An ALMA/NOEMA survey of the molecular gas properties of high-redshift star-forming galaxies

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    We have used ALMA and NOEMA to study the molecular gas reservoirs in 61 ALMA-identified submillimetre galaxies (SMGs) in the COSMOS, UDS, and ECDFS fields. We detect 12CO (⁠Jup= 2–5) emission lines in 50 sources, and [C I](3P1 − 3P0) emission in eight, at z= 1.2–4.8 and with a median redshift of 2.9 ± 0.2. By supplementing our data with literature sources, we construct a statistical CO spectral line energy distribution and find that the 12CO line luminosities in SMGs peak at Jup ∼ 6, consistent with similar studies. We also test the correlations of the CO, [C I], and dust as tracers of the gas mass, finding the three to correlate well, although the CO and dust mass as estimated from the 3-mm continuum are preferable. We estimate that SMGs lie mostly on or just above the star-forming main sequence, with a median gas depletion timescale, tdep = Mgas/SFR, of 210 ± 40 Myr for our sample. Additionally, tdep declines with redshift across z ∼ 1–5, while the molecular gas fraction, μgas = Mgas/M*, increases across the same redshift range. Finally, we demonstrate that the distribution of total baryonic mass and dynamical line width, Mbaryon–σ, for our SMGs is consistent with that followed by early-type galaxies in the Coma cluster, providing strong support to the suggestion that SMGs are progenitors of massive local spheroidal galaxies. On the basis of this, we suggest that the SMG populations above and below an 870-μm flux limit of S870 ∼ 5 mJy may correspond to the division between slow and fast rotators seen in local early-type galaxies

    Lessons Learnt From the 2009 Padang Indonesia, 2011 Tōhoku Japan and 2016 Muisne Ecuador Earthquakes

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    This paper presents the observations during the UK Earthquake Engineering Field Investigation Team (EEFIT)'s post-earthquake reconnaissance missions to the September 20, 2009 Padang (Mw7.6), March 11, 2011 Tōhoku (Mw9.0) and April 16, 2016 Muisne (Mw7.8) earthquakes. The performance of buildings and geotechnical structures within the affected regions were investigated to gain insights on their design and construction deficiencies. Findings on these damages observed are compared along with the characteristics of the earthquake and nature of building codes in these countries. They include building damages attributed to a combination of structural resonance, deficiencies in reinforcement detailing, vulnerability to soft story collapse, ground settlement, soil liquefaction, and landslides. It was demonstrated that buildings which were severely damaged had natural building frequencies coinciding with the dominant frequencies of the ground shaking. The locations of damage of several such buildings showed insufficient confining reinforcements and lapping of stirrup links. Soft story collapses were also observed in the three earthquakes, although many were attributed to old building codes that were less effective. In areas affected by the Muisne earthquake, soft story collapses were mainly found at mid height of the building rather than at the ground floor as observed in the Padang and Tōhoku earthquakes, likely due to extension of building long after the bottom floors were completed. Such extension of building can either lead to local reduction in capacity due to weaker concrete-rebar bonding, possibly insufficient lapping of reinforcement, as well as increased axial loads. In the aspect of geotechnical failure, foundations of buildings found on piles performed reasonably well, except for areas affected by soil liquefaction. Landslides occurred following these earthquakes led to large concentration of casualties and property losses, motivating the EEFIT teams to invest efforts in hazard mapping and ground-truthing exercises using satellite images at Padang and Muisne earthquakes respectively. Such geospatial tools applied in these three earthquakes were reviewed and demonstrated to be capable of identifying landslide sites and producing reliable landslide hazard map

    In Silico Investigation of Potential Src Kinase Ligands from Traditional Chinese Medicine

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    Src kinase is an attractive target for drug development based on its established relationship with cancer and possible link to hypertension. The suitability of traditional Chinese medicine (TCM) compounds as potential drug ligands for further biological evaluation was investigated using structure-based, ligand-based, and molecular dynamics (MD) analysis. Isopraeroside IV, 9alpha-hydroxyfraxinellone-9-O-beta-D-glucoside (9HFG) and aurantiamide were the top three TCM candidates identified from docking. Hydrogen bonds and hydrophobic interactions were the primary forces governing docking stability. Their stability with Src kinase under a dynamic state was further validated through MD and torsion angle analysis. Complexes formed by TCM candidates have lower total energy estimates than the control Sacaratinib. Four quantitative-structural activity relationship (QSAR) in silico verifications consistently suggested that the TCM candidates have bioactive properties. Docking conformations of 9HFG and aurantiamide in the Src kinase ATP binding site suggest potential inhibitor-like characteristics, including competitive binding at the ATP binding site (Lys295) and stabilization of the catalytic cleft integrity. The TCM candidates have significantly lower ligand internal energies and are estimated to form more stable complexes with Src kinase than Saracatinib. Structure-based and ligand-based analysis support the drug-like potential of 9HFG and aurantiamide and binding mechanisms reveal the tendency of these two candidates to compete for the ATP binding site

    Excess pore pressures around underground structures following earthquake induced liquefaction

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    Underground structures located in liquefiable soil deposits are susceptible to floatation following an earthquake event due to their lower unit weight relative to the surrounding saturated soil. This inherent buoyancy may cause lightweight structures to float when the soil liquefies. Centrifuge tests have been carried out to study the excess pore pressure generation and dissipation in liquefiable soils. In these tests, near full liquefaction conditions were attained within a few cycles of the earthquake loading. In the case of high hydraulic conductivity sands, significant dissipation could take place even during the earthquake loading which inhibits full liquefaction from occurring. In the case of excess pore pressure generation and dissipation around a floating structure, the cyclic response of the structure may lead to the reduction in excess pore pressure near the face of the structure as compared to the far field. This reduction in excess pore pressure is due to shear-induced dilation and suction pressures arising from extensile stresses at the soil-structure interface. Given the lower excess pore pressure around the structure; the soil around the structure retains a portion of this shear strength which in turn can discourage significant uplift of the underground structure. Copyright © 2012, IGI Global

    Influence of fluid viscosity on the response of buried structures in earthquakes

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    The use of high viscous pore fluid has been widely established to match the rate of excess pore pressure generation and subsequent dissipation in dynamic centrifuge tests. The appropriate viscosity is linked to the geometric and gravity scaling factors which corresponds to the use of pore fluid of 'N' cSt in a 'N'g centrifuge test. The use of either water (1 cSt) or pore fluid lower than 'N' cSt can influence the behaviour of soil liquefaction in a centrifuge test. In this paper, the floatation of a tunnel following soil liquefaction is investigated using pore fluids with two different viscosities. The results show that the uplift displacement of the tunnel is significantly affected by the pore fluid viscosity. © 2010 Taylor & Francis Group, London

    Effect of buried depth and diameter on uplift of underground structures in liquefied soils

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    In an earthquake, underground structures located in liquefiable soil deposits are susceptible to floatation following an earthquake event due to their lower unit weight relative to the surrounding saturated soil. The uplift displacement of an underground structure in liquefiable soil deposit can be affected by the buried depth and size of the structure. Dynamic centrifuge tests have been carried out to investigate the influence of these factors by measuring the uplift displacement of shallow model circular structures. Ratios for the buried depth and diameter effects of the structure are introduced to compare the uplift displacement in different soil and earthquake conditions. With the depth effect and diameter effect ratios, the uplift displacement of a buoyant structure in liquefiable soil can also be estimated based on performance of similar structures in comparable soil condition and subjected to a similar earthquake event. © 2012 Elsevier Ltd
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