1,557 research outputs found
The size, shape, and dynamics of cellular blebs
A cellular bleb grows when a portion of the cell membrane detaches from the
underlying cortex under the influence of a cytoplasmic pressure. We develop a
quantitative model for the growth and dynamics of these objects in a simple
two-dimensional setting. In particular, we first find the minimum cytoplasmic
pressure and minimum unsupported membrane length for a stationary bleb to
nucleate and grow as a function of the membrane-cortex adhesion. We next show
how a bleb may travel around the periphery of the cell when the cytoplasmic
pressure varies in space and time in a prescribed way and find that the
traveling speed is governed by the speed of the pressure change induced by
local cortical contraction while the shape of the traveling bleb is governed by
the speed of cortical healing. Finally, we relax the assumption that the
pressure change is prescribed and couple it hydrodynamically to the cortical
contraction and membrane deformation. By quantifying the phase space of bleb
formation and dynamics, our framework serves to delineate the range and scope
of bleb-associated cell motility and synthesizes a variety of experimental
observations
Travoprost Induced Granulomatous Anterior Uveitis
Purpose. To report a case of granulomatous anterior uveitis caused by travoprost. Methods. Single observational case report. Results. A 71-year-old who was fit and healthy presented with bilateral granulomatous anterior uveitis 2 months after he was started on travoprost in both eyes. There was no past history of uveitis. Blood test and radiological investigation were unremarkable. Travoprost was stopped. The uveitis resolved on topical steroid treatment. A rechallenge with travoprost was attempted in one eye. The inflammation recurred in this eye only. This subsided with the cessation of travoprost alone without topical steroid. Conclusion. This is the first case report of travoprost causing granulomatous anterior uveitis. The uveitis recurred with a rechallenge. Changing the prostaglandin analogue to another topical treatment may be adequate to cease the inflammation
Asia's Experience in the Quest for a Regional Human Rights Mechanism
The article outlines the development of a regional human rights charter in Asia. The article provides an historical overview of the efforts made to establish a charter, concluding that after fourteen UN workshops Asia still has not established any human rights mechanism. However, the author notes that some encouraging progress has been made. The article also identifies factors present in Asia that have hindered progress in establishing a regional mechanism and concludes with an outlook on how to proceed
Contingent Valuation Method: Valuing Cultural Heritage
Cultural heritage is not easy to be valued in a market because it is a very unique product which gives a
community (ies), nation(s) an identity and a sense of belonging. Debate on the valuation of cultural
heritage surrounds despite growing attention by economists and policy makers. The attention on the
estimation of economic values for cultural goods and services has been great by economics throughout
the past two decades (Choi, et al., 2009; Kaminski, McLoughlin, & Sodagar, 2007; Navrud & Ready,
2002, Noonan, 2003; Venkatachalam, 2004). The two stated preference methods which are commonly
used in valuing non-use goods; i.e. contingent valuation method and choice modelling. Each of these two
valuation method has its own strengths and weaknesses and may even complement each other
depending on the parameters of the study. However, according to Kaminski et al., 2007; Noonan, 2003,
the usage of choice modelling to estimate cultural values has been limited due to the growing usage of
contingent valuation. Therefore, this paper will discuss contingent valuation method in valuing amenities
and aim to contribute the knowledge on contingent valuation method for nonmarket goods. (Abstract by author
Controlling metamaterial resonances via dielectric and aspect ratio effects
We study ways to enhance the sensitivity and dynamic tuning range of the
fundamental inductor-capacitor (LC) resonance in split ring resonators (SRRs)
by controlling the aspect ratio of the SRRs and their substrate thickness. We
conclude that both factors can significantly affect the LC resonance. We show
that metafilms consisting of low height SRRs on a thin substrate are most
sensitive to changes in their dielectric environment and thus show excellent
potential for sensing applications.Comment: 4 pages with 4 figure
Economic valuation of conservation of living heritage in Melaka City, Malaysia using single-bounded and double-bounded dichotomous choice Contingent Valuation Method (CVM)
Power Quality Management and Classification for Smart Grid Application using Machine Learning
The Efficient Wavelet-based Convolutional Transformer network (EWT-ConvT) is proposed to detect power quality disturbances in time-frequency domain using attention mechanism. The support of machine learning further improves the network accuracy with synthetic signal generation and less system complexity under practical environment. The proposed EWT-ConvT can achieve 94.42% accuracy which is superior than other deep learning models. The detection of disturbances using EWT-ConvT can also be implemented into smart grid applications for real-time embedded system development
Children - Our Heritage
"An inaugural lecture delivered at the University of Malaya, Kuala Lumpur Thursday, January 23, 1992"
ENTREPRENEURSHIP INTENTION AMONG OPEN UNIVERSITY MALAYSIA (OUM) LEARNERS
Entrepreneurship plays an important role in
contributing to the nation economic growth and creates job
opportunities to the country. Ministry of education in
Malaysia has even included entrepreneurship as part of the
syllabus in higher learning education in order to foster
local entrepreneurs among learners.
Entrepreneurship education has become an
important curriculum in the higher education institutions in
Malaysia (Ismail et al., 2009) and a core subject for most
programmes in Malaysia. A subject by itself,
entrepreneurship, has been embedded into the programmes
and entrepreneurship is offered as a programme even in
several public and private higher education providers,
Open University Malaysia (OUM) too has a course under
the university compulsory category in the academic for all
offered programme in the curriculum called
Entrepreneurship with code OUMM2103. This course has
become popular and receptive by the undergraduates in
OUM. Entrepreneurship education has now become an
essential component to cultivate the potential entrepreneurs
in the higher learning institutions. According to Ismail et
al., (2009), entrepreneurship education is the most effective
way to promote the transition of graduates toward the selfemployment.
This study aims to investigate the factors which will
influence the entrepreneurship intention among OUM
learners using structural equation modeling (SEM). The
results of the finding shows there are a significant
influence of attitude and perceive behavioural control to
entrepreneurship intention. However, subjective norms do
not significantly influence the entrepreneurship intention
among OUM learners. The overall findings of this research
have limitations in terms to generalise the results. The
results of this study will be able to provide an insight to the
educators to help all learners to develop their abilities and
skills to produce a higher rate of entrepreneurs in the
nation. (Abstract by author
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