“Sixteen and a half”: a rare neurological syndrome

"Sixteen and a half" syndrome is a recently coined terminology for a novel pontine neuro-ophthalmological condition. It is characterised by "one and a half" syndrome with an additional ipsilateral seventh and eighth cranial nerve palsy (1½+7+8=16½). We hereby present a case with "sixteen and a half" syndrome, characterised by facial asymmetry, conjugate gaze palsy and unilateral deafness with vertigo. As demonstrated by magnetic resonance imaging, the responsible pontine lesion was a brainstem tuberculoma involving the ipsilateral abducens nucleus and the adjacent medial longitudinal fasciculus (MLF), along with facial and vestibulocochlear nerve. The location of the tuberculoma and the clinical presentation is unusual

From 1 Sun to 10 Suns c-Si Cells by Optimizing Metal Grid, Metal Resistance, and Junction Depth

Use of a solar cell in concentrator PV technology requires reduction in its series resistance in order to minimize the resistive power losses. The present paper discusses a methodology of reducing the series resistance of a commercial c-Si solar cell for concentrator applications, in the range of 2 to 10 suns. Step by step optimization of commercial cell in terms of grid geometry, junction depth, and electroplating of the front metal contacts is proposed. A model of resistance network of solar cell is developed and used for the optimization. Efficiency of unoptimized commercial cell at 10 suns drops by 30% of its 1 sun value corresponding to resistive power loss of about 42%. The optimized cell with grid optimization, junction optimization, electroplating, and junction optimized with electroplated contacts cell gives resistive power loss of 20%, 16%, 11%, and 8%, respectively. An efficiency gain of 3% at 10 suns for fully optimized cell is estimated

Time as a supervisor: temporal regularity and auditory object learning

Sensory systems appear to learn to transform incoming sensory information into perceptual representations, or “objects,” that can inform and guide behavior with minimal explicit supervision. Here, we propose that the auditory system can achieve this goal by using time as a supervisor, i.e., by learning features of a stimulus that are temporally regular. We will show that this procedure generates a feature space sufficient to support fundamental computations of auditory perception. In detail, we consider the problem of discriminating between instances of a prototypical class of natural auditory objects, i.e., rhesus macaque vocalizations. We test discrimination in two ethologically relevant tasks: discrimination in a cluttered acoustic background and generalization to discriminate between novel exemplars. We show that an algorithm that learns these temporally regular features affords better or equivalent discrimination and generalization than conventional feature-selection algorithms, i.e., principal component analysis and independent component analysis. Our findings suggest that the slow temporal features of auditory stimuli may be sufficient for parsing auditory scenes and that the auditory brain could utilize these slowly changing temporal features

AN ANALYTICAL STUDY OF HOSPITALITY INDUSTRY WITH SPECIAL REFERENCE TO SOCIAL MEDIA MARKETING AS A PROMOTIONAL TOOL

The Modernization and digitalization of World has evolved with the new dimension of the Business and Especially in the field of Social Media Marketing. Social Media Marketing has emerged as one of the most important and effective tool for the promotion of the products for the business units. In this paper Researcher has explained the importance of Social Media Marketing as emerging tools of marketing in Hospitality Industry. The digitalization initiative of Government of India has resulted the fruitful outcome for hospitality industry in term of Hotel Bookings. The Paper Also Consists of the data analysis of the various influencing factors affecting the buying decisions for the traveller for booking the hotels. The paper also consist the behavioural patterns of the traveller in reactions of the Social Media Marketing and Advertisement and SEO Operations of Booking Platforms and Hoteliers

An Analytical Study of Hospitality Industry with Special Reference to Social Media Marketing as a Promotional Tool

The Modernization and digitalization of World has evolved with the new dimension of the Business and Especially in the field of Social Media Marketing. Social Media Marketing has emerged as one of the most important and effective tool for the promotion of the products for the business units. In this paper Researcher has explained the importance of Social Media Marketing as emerging tools of marketing in Hospitality Industry. The digitalization initiative of Government of India has resulted the fruitful outcome for hospitality industry in term of Hotel Bookings. The Paper Also Consists of the data analysis of the various influencing factors affecting the buying decisions for the traveller for booking the hotels. The paper also consist the behavioural patterns of the traveller in reactions of the Social Media Marketing and Advertisement and SEO Operations of Booking Platforms and Hoteliers

Construction of a <it>Salmonella</it> Gallinarum ghost as a novel inactivated vaccine candidate and its protective efficacy against fowl typhoid in chickens

Abstract In order to develop a novel, safe and immunogenic fowl typhoid (FT) vaccine candidate, a Salmonella Gallinarum ghost with controlled expression of the bacteriophage PhiX174 lysis gene E was constructed using pMMP99 plasmid in this study. The formation of the Salmonella Gallinarum ghost with tunnel formation and loss of cytoplasmic contents was observed by scanning electron microscopy and transmission electron microscopy. No viable cells were detectable 24 h after the induction of gene E expression by an increase in temperature from 37 °C to 42 °C. The safety and protective efficacy of the Salmonella Gallinarum ghost vaccine was tested in chickens that were divided into four groups: group A (non-immunized control), group B (orally immunized), group C (subcutaneously immunized) and group D (intramuscularly immunized). The birds were immunized at day 7 of age. None of the immunized animals showed any adverse reactions such as abnormal behavior, mortality, or signs of FT such as anorexia, depression, or diarrhea. These birds were subsequently challenged with a virulent Salmonella Gallinarum strain at 3 weeks post-immunization (wpi). Significant protection against the virulent challenge was observed in all immunized groups based on mortality and post-mortem lesions compared to the non-immunized control group. In addition, immunization with the Salmonella Gallinarum ghosts induced significantly high systemic IgG response in all immunized groups. Among the groups, orally-vaccinated group B showed significantly higher levels of secreted IgA. A potent antigen-specific lymphocyte activation response along with significantly increased percentages of CD4+ and CD8+ T lymphocytes found in all immunized groups clearly indicate the induction of cellular immune responses. Overall, these findings suggest that the newly constructed Salmonella Gallinarum ghost appears to be a safe, highly immunogenic, and efficient non-living bacterial vaccine candidate that protects against FT.</p

Cone beam computed tomography : extending its arm to explore new possibilities

Purpose: To determine whether the greyscale value depicted in cone beam computed tomography (CBCT) differentiates different benign osseous lesions of jaws and to measure the greyscale value of various osseous lesions of jaws and to find the correlation (if any) of these greyscale values to that of histopathological diagnosis. Material and methods: This study was conducted in the Department of Oral Medicine and Radiology of the Dental Institute after obtaining approval from the Ethical Committee. CBCT scans of osseous lesions of jaws confirmed with histopathological reports depicting cystic or tumour-like lesions were included in the study. Greyscale values depicted in CBCT scans of osseous lesions were measured. The greyscale values were grouped as per the histopathological diagnosis, and these ranges were then tabulated and statistically evaluated. Results: The mean value with standard deviation of greyscale values for cystic lesions was 1208.375 ± 93 and for that of the tumour group was 1603 ± 425.5. Conclusions: The greyscale value is a useful tool in differentiating between different groups of osseous lesions of jaws