439 research outputs found
Small-worlds: How and why
We investigate small-world networks from the point of view of their origin.
While the characteristics of small-world networks are now fairly well
understood, there is as yet no work on what drives the emergence of such a
network architecture. In situations such as neural or transportation networks,
where a physical distance between the nodes of the network exists, we study
whether the small-world topology arises as a consequence of a tradeoff between
maximal connectivity and minimal wiring. Using simulated annealing, we study
the properties of a randomly rewired network as the relative tradeoff between
wiring and connectivity is varied. When the network seeks to minimize wiring, a
regular graph results. At the other extreme, when connectivity is maximized, a
near random network is obtained. In the intermediate regime, a small-world
network is formed. However, unlike the model of Watts and Strogatz (Nature {\bf
393}, 440 (1998)), we find an alternate route to small-world behaviour through
the formation of hubs, small clusters where one vertex is connected to a large
number of neighbours.Comment: 20 pages, latex, 9 figure
Neoliberalism and Justice in Education for Sustainable Development: A Call for Inclusive Pluralism
Global Challenges (FSW
Performance of networks of artificial neurons: The role of clustering
The performance of the Hopfield neural network model is numerically studied
on various complex networks, such as the Watts-Strogatz network, the
Barab{\'a}si-Albert network, and the neuronal network of the C. elegans.
Through the use of a systematic way of controlling the clustering coefficient,
with the degree of each neuron kept unchanged, we find that the networks with
the lower clustering exhibit much better performance. The results are discussed
in the practical viewpoint of application, and the biological implications are
also suggested.Comment: 4 pages, to appear in PRE as Rapid Com
Is there an integrative center in the vertebrate brain-stem? A robotic evaluation of a model of the reticular formation viewed as an action selection device
Neurobehavioral data from intact, decerebrate, and neonatal rats, suggests that the reticular formation provides
a brainstem substrate for action selection in the vertebrate central nervous system. In this article, Kilmer,
McCulloch and Blum’s (1969, 1997) landmark reticular formation model is described and re-evaluated, both in
simulation and, for the first time, as a mobile robot controller. Particular model configurations are found to
provide effective action selection mechanisms in a robot survival task using either simulated or physical robots.
The model’s competence is dependent on the organization of afferents from model sensory systems, and a genetic
algorithm search identified a class of afferent configurations which have long survival times. The results support
our proposal that the reticular formation evolved to provide effective arbitration between innate behaviors
and, with the forebrain basal ganglia, may constitute the integrative, ’centrencephalic’ core of vertebrate brain
architecture. Additionally, the results demonstrate that the Kilmer et al. model provides an alternative form of
robot controller to those usually considered in the adaptive behavior literature
Robot companion cats for people at home with dementia: a qualitative case study on companotics
The use of robot companion pets for people in care homes has been extensively studied. The results are largely positive, and suggest that they are valuable in enhancing wellbeing, communication and behavioural aspects. However, there has been little research in people’s own homes, possibly due to the cost and complexity of some of the robot pets currently available. As dementia affects people in different ways, this study explores the effects of a robot cat for people in their own homes, without specifically investigating the effects on a particular symptom. We utilised a case study design to investigate the proposition that various factors influence the impact of a robot cat on the person living with dementia and their carer, including acceptability of the robot pet and acceptance of dementia and its symptoms. The qualitative analysis explores the similarities and differences within the data which were gathered during interviews with people with dementia and their families. This analysis revealed four themes: Distraction, Communication, Acceptance and rejection, and Connecting with the cat and connecting with others. These themes were synthesized into two overarching themes: The effect of the cat on mood and behaviour, and The interaction with the cat. We present the acceptability and impact of the robot cat on symptoms of dementia, with data presented across and within the group of participants. Our analysis suggests that benefits of the robot pet were evident, and although this was a small-scale study, where they were accepted, robot pets provided positive outcomes for the participants and their families
Experimental modulation of capsule size in Cryptococcus neoformans
Experimental modulation of capsule size is an important technique for the study of the virulence of the encapsulated pathogen Cryptococcus neoformans. In this paper, we summarize the techniques available for experimental modulation of capsule size in this yeast and describe improved methods to induce capsule size changes. The response of the yeast to the various stimuli is highly dependent on the cryptococcal strain. A high CO(2) atmosphere and a low iron concentration have been used classically to increase capsule size. Unfortunately, these stimuli are not reliable for inducing capsular enlargement in all strains. Recently we have identified new and simpler conditions for inducing capsule enlargement that consistently elicited this effect. Specifically, we noted that mammalian serum or diluted Sabouraud broth in MOPS buffer pH 7.3 efficiently induced capsule growth. Media that slowed the growth rate of the yeast correlated with an increase in capsule size. Finally, we summarize the most commonly used media that induce capsule growth in C. neoformans
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