Vibratory and perceptual measurement of resonant voice

Purpose: This study set out to investigate whether there existed a correlation between auditory-perceptual judgment of resonant voice and the physical vibration in the facial bone. The magnitude of bone vibration in the facial bone during different types of voice production (resonant vs nonresonant vs strained voices) was also investigated. Method: Thirty-six healthy normal subjects produced three types of phonations: resonant voice, habitual nonresonant voice, and strained voice. A piezoelectric accelerometer was used to measure the vibrations in the nasal bridge and the perilaryngeal area during the phonation. Seventy-two selected nasal sounds (/ma/) produced under the resonant voice condition by these speakers were rated by two experienced speech pathologists on the magnitude of auditory-perceptual resonance using an 11-point equal-appearing interval scale. The magnitude of bone vibration was also compared across the three voice types. Results: Significant moderate correlations were found between the physical bone vibration and the auditory-perceptual rating of resonant voice at the nasal bridge of the facial bone (0.6). Resonant voice, compared with the strained and nonresonant voice types, was also found to have a significant increase in the magnitude of facial bone vibration. Nasal stimuli, compared with nonnasal stimuli, facilitated greater bone vibration during resonant voice production. Conclusion: Piezoelectric accelerometer, as an objective quantitative tool, measures reliably the extent of bone vibration in resonant voice phonation. It is a useful tool for determining the bone vibration in relation to resonant voice. © 2012 The Voice Foundation.postprin

Code coverage of adaptive random testing

Random testing is a basic software testing technique that can be used to assess the software reliability as well as to detect software failures. Adaptive random testing has been proposed to enhance the failure-detection capability of random testing. Previous studies have shown that adaptive random testing can use fewer test cases than random testing to detect the first software failure. In this paper, we evaluate and compare the performance of adaptive random testing and random testing from another perspective, that of code coverage. As shown in various investigations, a higher code coverage not only brings a higher failure-detection capability, but also improves the effectiveness of software reliability estimation. We conduct a series of experiments based on two categories of code coverage criteria: structure-based coverage, and fault-based coverage. Adaptive random testing can achieve higher code coverage than random testing with the same number of test cases. Our experimental results imply that, in addition to having a better failure-detection capability than random testing, adaptive random testing also delivers a higher effectiveness in assessing software reliability, and a higher confidence in the reliability of the software under test even when no failure is detected

How can non-technical end users effectively test their spreadsheets?

Purpose – An alarming number of spreadsheet faults have been reported in the literature, indicating that effective and easy-to-apply spreadsheet testing techniques are not available for “non-technical,” end-user programmers. The purpose of this paper is to alleviate the problem by introducing a metamorphic testing (MT) technique for spreadsheets. Design/methodology/approach – The paper discussed four common challenges encountered by end-user programmers when testing a spreadsheet. The MT technique was then discussed and how it could be used to solve the common challenges was explained. An experiment involving several “real-world” spreadsheets was performed to determine the viability and effectiveness of MT. Findings – The experiment confirmed that MT is highly effective in spreadsheet fault detection, and yet MT is a general technique that can be easily used by end-user programmers to test a large variety of spreadsheet applications. Originality/value – The paper provides a detailed discussion of some common challenges of spreadsheet testing encountered by end-user programmers. To the best of the authors knowledge, the paper is the first that includes an empirical study of how effective MT is in spreadsheet fault detection from an end-user programmer's perspective

π Junction to probe antiphase s-Wave pairing in iron pnictide superconductors

Josephson junctions between a FeAs-based superconductor with antiphase s-wave pairing and a conventional s-wave superconductor are studied. The translational invariance in a planar junction between a single crystal pnictide and an aluminum metal greatly enhances the relative weight of electron pockets in the pnictide to the critical current. In a wide doping region of the pnictide, a planar and a point contact junction have opposite phases, which can be used to design a trijunction ring with π phase to probe the antiphase pairing. © 2009 The American Physical Society.published_or_final_versio

How effectively does metamorphic testing alleviate the oracle problem?

In software testing, something which can verify the correctness of test case execution results is called an oracle. The oracle problem occurs when either an oracle does not exist, or exists but is too expensive to be used. Metamorphic testing is a testing approach which uses metamorphic relations, properties of the software under test represented in the form of relations among inputs and outputs of multiple executions, to help verify the correctness of a program. This paper presents new empirical evidence to support this approach, which has been used to alleviate the oracle problem in various applications and to enhance several software analysis and testing techniques. It has been observed that identification of a sufficient number of appropriate metamorphic relations for testing, even by inexperienced testers, was possible with a very small amount of training. Furthermore, the cost-effectiveness of the approach could be enhanced through the use of more diverse metamorphic relations. The empirical studies presented in this paper clearly show that a small number of diverse metamorphic relations, even those identified in an ad hoc manner, had a similar fault-detection capability to a test oracle, and could thus effectively help alleviate the oracle problem

Perceived threats of vision impairment and its effect on consumption pattern of dietary supplement of lutein and zeaxanthin

Purpose: To explore perceived threats of vision impairment as well as the perceived benefits and barriers of lutein-containing supplements using a health belief model (HBM), and also to assess how these may affect dietary supplement consumption behaviours. Methods: A structured questionnaire was developed on HBM through a focus group interview to gather information from 1,075 drugstore customers in Taiwan. Respondents were 55.16 % female, 64.47 % married, 53.12 % aged between 31 and 50 years, and 91 % with at least a high school education. Results: Perceived severity was much higher that perceived susceptibility. Susceptibility was the most stable construct. Occupation, residence area, and workplace were the top three factors differentiating the variance in HBM constructs. Perceived benefits appeared as the most powerful predictor, followed by perceived barriers. HBM predictors jointly explained 21.9 % of the variance in lutein- and zeaxanthintaking behaviour. Moderating effects of health-related information were not significant. Conclusion: HBM is useful to understand this behaviour. Consumer behaviour is mainly affected by perceived benefits, and not the threat of vision impairment. Since people ignore the possibility of suffering severe vision impairment, more health education is required

Fiber Orientation Estimation Guided by a Deep Network

Diffusion magnetic resonance imaging (dMRI) is currently the only tool for noninvasively imaging the brain's white matter tracts. The fiber orientation (FO) is a key feature computed from dMRI for fiber tract reconstruction. Because the number of FOs in a voxel is usually small, dictionary-based sparse reconstruction has been used to estimate FOs with a relatively small number of diffusion gradients. However, accurate FO estimation in regions with complex FO configurations in the presence of noise can still be challenging. In this work we explore the use of a deep network for FO estimation in a dictionary-based framework and propose an algorithm named Fiber Orientation Reconstruction guided by a Deep Network (FORDN). FORDN consists of two steps. First, we use a smaller dictionary encoding coarse basis FOs to represent the diffusion signals. To estimate the mixture fractions of the dictionary atoms (and thus coarse FOs), a deep network is designed specifically for solving the sparse reconstruction problem. Here, the smaller dictionary is used to reduce the computational cost of training. Second, the coarse FOs inform the final FO estimation, where a larger dictionary encoding dense basis FOs is used and a weighted l1-norm regularized least squares problem is solved to encourage FOs that are consistent with the network output. FORDN was evaluated and compared with state-of-the-art algorithms that estimate FOs using sparse reconstruction on simulated and real dMRI data, and the results demonstrate the benefit of using a deep network for FO estimation.Comment: A shorter version is accepted by MICCAI 201

Genetic steps to organ laterality in zebrafish.

All internal organs are asymmetric along the left-right axis. Here we report a genetic screen to discover mutations which perturb organ laterality. Our particular focus is upon whether, and how, organs are linked to each other as they achieve their laterally asymmetric positions. We generated mutations by ENU mutagenesis and examined F3 progeny using a cocktail of probes that reveal early primordia of heart, gut, liver and pancreas. From the 750 genomes examined, we isolated seven recessive mutations which affect the earliest left-right positioning of one or all of the organs. None of these mutations caused discernable defects elsewhere in the embryo at the stages examined. This is in contrast to those mutations we reported previously (Chen et al., 1997) which, along with left-right abnormalities, cause marked perturbation in gastrulation, body form or midline structures. We find that the mutations can be classified on the basis of whether they perturb relationships among organ laterality. In Class 1 mutations, none of the organs manifest any left-right asymmetry. The heart does not jog to the left and normally leftpredominant BMP4 in the early heart tube remains symmetric. The gut tends to remain midline. There frequently is a remarkable bilateral duplication of liver and pancreas. Embryos with Class 2 mutations have organotypic asymmetry but, in any given embryo, organ positions can be normal, reversed or randomized. Class 3 reveals a hitherto unsuspected gene that selectively affects laterality of heart. We find that visceral organ positions are predicted by the direction of the preceding cardiac jog. We interpret this as suggesting that normally there is linkage between cardiac and visceral organ laterality. Class 1 mutations, we suggest, effectively remove the global laterality signals, with the consequence that organ positions are effectively symmetrical. Embryos with Class 2 mutations do manifest linkage among organs, but it may be reversed, suggesting that the global signals may be present but incorrectly orientated in some of the embryos. That laterality decisions of organs may be independently perturbed, as in the Class 3 mutation, indicates that there are distinctive pathways for reception and organotypic interpretation of the global signals

Automated functional testing of online search services

Search services are the main interface through which people discover information on the Internet. A fundamental challenge in testing search services is the lack of oracles. The sheer volume of data on the Internet prohibits testers from verifying the results. Furthermore, it is difficult to objectively assess the ranking quality because different assessors can have very different opinions on the relevance of a Web page to a query. This paper presents a novel method for automatically testing search services without the need of a human oracle. The experimental findings reveal that some commonly used search engines, including Google, Yahoo!, and Live Search, are not as reliable as what most users would expect. For example, they may fail to find pages that exist in their own repositories, or rank pages in a way that is logically inconsistent. Suggestions are made for search service providers to improve their service quality. Copyright © 2010 John Wiley & Sons, Ltd. A novel method for automatically testing search services without the need of a human oracle is presented. The experimental findings reveal that some commonly used search engines, including Google, Yahoo!, and Live Search, are not as reliable as what most users would expect. For example, they may fail to find pages that exist in their own repositories, or rank pages in a way that is logically inconsistent. Suggestions are made for search service providers to improve their service quality. Copyright © 2010 John Wiley & Sons, Ltd.link_to_subscribed_fulltex

First record of the bacterial endosymbiont Wolbachia for phytophagous hoverflies from genus Merodon (Diptera : Syrphidae)

Wolbachia is a widespread bacterial endosymbiont among arthropod species. It influences the reproduction of the host species and also mitochondrial DNA diversity. Until now there were only a few studies that detected Wolbachia infections in hoverflies (Diptera: Syrphidae), and this is the first broader study with the aim of examining the incidence of Wolbachia in the hoverfly genus Merodon. The obtained results indicate an infection rate of 96% and the presence of both Wolbachia supergroup A and B, which are characteristic for most of the infected arthropod species. Additionally, the presence of multiple Wolbachia strains in the Merodon aureus group species was detected and the mitochondrial DNA COI-based relationships of the group are discussed in the light of infection. Finally, we discuss plant-mediated horizontal transmission of Wolbachia strains among the studied hoverfly species.Peer reviewe