5,089 research outputs found

    Depositing catalyst layers in polymer electrolyte membrane fuel cells : a review

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    Fuel cell technology continues to advance and offers to be a potentially promising solution to many energy needs. Of particular interest are manufacturing techniques to improve performance and decrease overall cost. For catalyst deposition on the membrane electrode assembly (MEA), there are a number of techniques that have been used in the past decades. This paper aims to review many of these main techniques that have been published to show the wide variety of catalyst deposition methods

    Enterprise Modelling: A Declarative Approach for FBPML

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    The University of Edinburgh and research sponsors are authorised to reproduce and distribute reprints and on-line copies for their purposes notwithstanding any copyright annotation hereon. The views and conclusions contained herein are the author’s and shouldn’t be interpreted as necessarily representing the official policies or endorsements, either expressed or implied, of other parties.Enterprise Modelling (EM) methods are well-recognised for their value in describing complex, informal domains in an organised structure. EM methods are used in practice, particularly during the early stages of software system development, e.g. during the phase of business requirements elicitation. The built model, however, has not always provided direct input to software system development. Despite the provision of adequate training to understand and use EM methods, informality is often seen in enterprise models and presents a major obstacle. This paper focuses on one type of EM methods: business process modelling (BPM) methods. We advocate the use of a BPM language within a three-layer framework. The BPM language merges two main and complimentary business process representations, IDEF3 and PSL, to introduce a Fundamental Business Process Modelling Language (FBPML) that is designed for simplicity of use and under-pinned by rich formality that may be used directly to support software and workflow system development

    Heterotopic ossification after patellar tendon repair in a man with trisomy 8 mosaicism: a case report and literature review

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    <p>Abstract</p> <p>Introduction</p> <p>Heterotopic ossification is the abnormal formation of lamellar bone in soft tissue. Its presence jeopardizes functional outcome, impairs rehabilitation and increases costs due to subsequent surgical interventions.</p> <p>Case presentation</p> <p>We present a case of a 32-year-old African-American man with trisomy 8 mosaicism who developed severe heterotopic ossification of his right extensor mechanism subsequent to repair of a patellar tendon rupture.</p> <p>Conclusion</p> <p>To the best of our knowledge there are no prior reports of heterotopic ossification as a complication of patellar tendon repair. This case may suggest an association between trisomy 8 mosaicism and increased risk of heterotopic ossification.</p

    Are autistic traits measured equivalently in individuals with and without an Autism Spectrum Disorder?:An invariance analysis of the Autism Spectrum Quotient Short Form

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    It is common to administer measures of autistic traits to those without autism spectrum disorders (ASDs) with, for example, the aim of understanding autistic personality characteristics in non-autistic individuals. Little research has examined the extent to which measures of autistic traits actually measure the same traits in the same way across those with and without an ASD. We addressed this question using a multi-group confirmatory factor invariance analysis of the Autism Quotient Short Form (AQ-S: Hoekstra et al. in J Autism Dev Disord 41(5):589-596, 2011) across those with (n = 148) and without (n = 168) ASD. Metric variance (equality of factor loadings), but not scalar invariance (equality of thresholds), held suggesting that the AQ-S measures the same latent traits in both groups, but with a bias in the manner in which trait levels are estimated. We, therefore, argue that the AQ-S can be used to investigate possible causes and consequences of autistic traits in both groups separately, but caution is due when combining or comparing levels of autistic traits across the two group

    Neurosurgeons Deliver Similar Quality Care Regardless of First Assistant Type: Resident Physician versus Nonphysician Surgical Assistant

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    OBJECTIVE: There are limited data evaluating the out-comes of attending neurosurgeons with different types of first assistants. This study considers a common neurosurgical procedure (single-level, posterior-only lumbar fusion surgery) and examines whether attending surgeons deliver equal patient outcomes, regardless of the type of first assistant (resident physician vs. nonphysician surgical assistant [NPSA]), among otherwise exact-matched patients. -METHODS: The authors retrospectively analyzed 3395 adult patients undergoing single-level, posterior-only lumbar fusion at a single academic medical center. Primary outcomes included readmissions, emergency department visits, reoperation, and mortality within 30 and 90 days after surgery. Secondary outcome measures included discharge disposition, length of stay, and length of surgery. Coarsened exact matching was used to match patients on key demographics and baseline characteristics known to independently affect neurosurgical outcomes. -RESULTS: Among exact-matched patients (n [ 1402), there was no significant difference in adverse postsurgical events (readmission, emergency department visits, reoperation, or mortality) within 30 days or 90 days of the index operation between patients who had resident physicians and those who had NPSAs as first assistants. Patients who had resident physicians as first assistants demonstrated a longer length of stay (mean: 100.0 vs. 87.4 hours, P \u3c 0.001) and a shorter duration of surgery (mean: 187.4 vs. 213.8 minutes, P \u3c 0.001). There was no significant difference between the two groups in the percentage of patients discharged home. -CONCLUSIONS: For single-level posterior spinal fusion, in the setting described, there are no differences in short-term patient outcomes delivered by attending surgeons assisted by resident physicians versus NPSAs

    An Overview of Chip Multi-Processors Simulators Technology

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    Computer System Architecture (CSA) simulators are generally used to develop and validate new CSA designs and developments. The goal of this paper is to provide an insight into the importance of CSA simulation and the possible criteria that differentiate between various CSA simulators. Multi-dimensional aspects determine the taxonomy of CSA simulators including their accuracy, performance, functionality and flexibility. The Sniper simulator has been selected for a closer look and testing. The Sniper proofs its ability to scale to hundred cores with a wide range of functionality and performance. © Springer International Publishing Switzerland 2015

    Terahertz underdamped vibrational motion governs protein-ligand binding in solution

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    Low-frequency collective vibrational modes in proteins have been proposed as being responsible for efficiently directing biochemical reactions and biological energy transport. However, evidence of the existence of delocalized vibrational modes is scarce and proof of their involvement in biological function absent. Here we apply extremely sensitive femtosecond optical Kerr-effect spectroscopy to study the depolarized Raman spectra of lysozyme and its complex with the inhibitor triacetylchitotriose in solution. Underdamped delocalized vibrational modes in the terahertz frequency domain are identified and shown to blue-shift and strengthen upon inhibitor binding. This demonstrates that the ligand-binding coordinate in proteins is underdamped and not simply solvent-controlled as previously assumed. The presence of such underdamped delocalized modes in proteins may have significant implications for the understanding of the efficiency of ligand binding and protein–molecule interactions, and has wider implications for biochemical reactivity and biological function
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